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cyproheptadine and Subarachnoid Hemorrhage

cyproheptadine has been researched along with Subarachnoid Hemorrhage in 2 studies

Cyproheptadine: A serotonin antagonist and a histamine H1 blocker used as antipruritic, appetite stimulant, antiallergic, and for the post-gastrectomy dumping syndrome, etc.
cyproheptadine : The product resulting from the formal oxidative coupling of position 5 of 5H-dibenzo[a,d]cycloheptene with position 4 of 1-methylpiperidine resulting in the formation of a double bond between the two fragments. It is a sedating antihistamine with antimuscarinic and calcium-channel blocking actions. It is used (particularly as the hydrochloride sesquihydrate) for the relief of allergic conditions including rhinitis, conjunctivitis due to inhalant allergens and foods, urticaria and angioedema, and in pruritic skin disorders. Unlike other antihistamines, it is also a seratonin receptor antagonist, making it useful in conditions such as vascular headache and anorexia.

Subarachnoid Hemorrhage: Bleeding into the intracranial or spinal SUBARACHNOID SPACE, most resulting from INTRACRANIAL ANEURYSM rupture. It can occur after traumatic injuries (SUBARACHNOID HEMORRHAGE, TRAUMATIC). Clinical features include HEADACHE; NAUSEA; VOMITING, nuchal rigidity, variable neurological deficits and reduced mental status.

Research Excerpts

ExcerptRelevanceReference
"This vasospasm was essentially unaffected by intravenous cyproheptadine."1.26Cerebrovascular responses to subarachnoid blood and serotonin in the monkey. ( Boisvert, DP; Grace, MG; Overton, TR; Reiffenstein, RJ; Weir, BK, 1979)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19902 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Boisvert, DP1
Weir, BK1
Overton, TR1
Reiffenstein, RJ1
Grace, MG1
Simpson, RK1
Fischer, DK1
Ehni, BL1

Other Studies

2 other studies available for cyproheptadine and Subarachnoid Hemorrhage

ArticleYear
Cerebrovascular responses to subarachnoid blood and serotonin in the monkey.
    Journal of neurosurgery, 1979, Volume: 50, Issue:4

    Topics: Animals; Brain Ischemia; Cerebrovascular Circulation; Cyproheptadine; Disease Models, Animal; Female

1979
Neurogenic hyperthermia in subarachnoid hemorrhage.
    Southern medical journal, 1989, Volume: 82, Issue:12

    Topics: Adult; Combined Modality Therapy; Cyproheptadine; Fever; Humans; Indomethacin; Ischemic Attack, Tran

1989