cyproheptadine has been researched along with Stomach Ulcer in 9 studies
Cyproheptadine: A serotonin antagonist and a histamine H1 blocker used as antipruritic, appetite stimulant, antiallergic, and for the post-gastrectomy dumping syndrome, etc.
cyproheptadine : The product resulting from the formal oxidative coupling of position 5 of 5H-dibenzo[a,d]cycloheptene with position 4 of 1-methylpiperidine resulting in the formation of a double bond between the two fragments. It is a sedating antihistamine with antimuscarinic and calcium-channel blocking actions. It is used (particularly as the hydrochloride sesquihydrate) for the relief of allergic conditions including rhinitis, conjunctivitis due to inhalant allergens and foods, urticaria and angioedema, and in pruritic skin disorders. Unlike other antihistamines, it is also a seratonin receptor antagonist, making it useful in conditions such as vascular headache and anorexia.
Stomach Ulcer: Ulceration of the GASTRIC MUCOSA due to contact with GASTRIC JUICE. It is often associated with HELICOBACTER PYLORI infection or consumption of nonsteroidal anti-inflammatory drugs (NSAIDS).
| Excerpt | Relevance | Reference |
|---|---|---|
| "A continuous multiclinical, randomized and prospective study has been carried out in our department to compare the efficacy of different cytoprotective (sucralfate, DE-NOL, Vitamin A) and antisecretory drugs (atropine, cimetidine, ranitidine, famotidine, pirenzepine) on ulcer healing in patients with chronic gastric ulcer (GU) and duodenal ulcer (DU)." | 5.07 | Dynamism of cytoprotective and antisecretory drugs in patients with unhealed gastric and duodenal ulcers. ( Garamszegi, M; Hunyady, B; Mózsik, G; Németh, A; Pakodi, F; Vincze, A, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (44.44) | 18.7374 |
| 1990's | 5 (55.56) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Patty, I | 1 |
| Benedek, S | 1 |
| Deák, G | 1 |
| Jávor, T | 1 |
| Kenéz, P | 1 |
| Morón, F | 1 |
| Nagy, L | 1 |
| Simon, L | 1 |
| Tárnok, F | 1 |
| Mózsik, G | 2 |
| Manekar, MS | 1 |
| Waghmare, ML | 1 |
| Koriakina, LA | 2 |
| Hunyady, B | 1 |
| Garamszegi, M | 1 |
| Németh, A | 1 |
| Pakodi, F | 1 |
| Vincze, A | 1 |
| Ohta, Y | 1 |
| Kobayashi, T | 1 |
| Ishiguro, I | 1 |
| Ogle, CW | 1 |
| Hui, SC | 1 |
| Qiu, BS | 1 |
| Li, KM | 1 |
| Karevina, TG | 1 |
| Khokholia, VP | 1 |
| Shevchuk, IM | 1 |
| Murashko, VV | 1 |
| Zhuravlev, AK | 1 |
| Shylle, ChI | 1 |
| Shabashova, NI | 1 |
| Skliarova, MA | 1 |
2 trials available for cyproheptadine and Stomach Ulcer
| Article | Year |
|---|---|
Cytoprotective effect of vitamin A and its clinical importance in the treatment of patients with chronic gastric ulcer.
Topics: Antacids; Chronic Disease; Cyproheptadine; Drug Therapy, Combination; Gastric Mucosa; Humans; Prospe | 1983 |
Dynamism of cytoprotective and antisecretory drugs in patients with unhealed gastric and duodenal ulcers.
Topics: Antacids; Anti-Ulcer Agents; Atropine; Chronic Disease; Cyproheptadine; Duodenal Ulcer; Humans; Pros | 1994 |
7 other studies available for cyproheptadine and Stomach Ulcer
| Article | Year |
|---|---|
Pharmacological study of aspirin induced acute gastric ulceration in rabbit.
Topics: Animals; Aspirin; Atropine; Cyproheptadine; Guinea Pigs; Rabbits; Rats; Species Specificity; Stomach | 1980 |
[The participation of serotonin S2 receptors in realizing the effects of stress on ulcer formation in the gastric mucosa of inbred mice].
Topics: 5-Hydroxytryptophan; Animals; Creatinine; Cyproheptadine; Drug Combinations; Gastric Mucosa; Genotyp | 1994 |
[A comparison of the effects of cyproheptadine and propranolol on the development of poststressor lesions of the gastric mucosa in inbred mice].
Topics: Animals; Creatinine; Cyproheptadine; Drug Combinations; Gastric Mucosa; Injections, Intraventricular | 1993 |
Role of endogenous serotonin and histamine in the pathogenesis of gastric mucosal lesions in unanaesthetised rats with a single treatment of compound 48/80, a mast cell degranulator.
Topics: Adrenergic Uptake Inhibitors; Amitriptyline; Animals; Cell Degranulation; Cimetidine; Cyproheptadine | 1999 |
5-Hydroxytryptamine3-receptor blockade protects against gastric mucosal damage in rats.
Topics: Animals; Cold Temperature; Cyproheptadine; Dose-Response Relationship, Drug; Ethanol; Female; Gastri | 1992 |
[Effects of serotonin and stress on the state of the gastric mucosa in rats with the intact and transsected vagus nerve].
Topics: Animals; Cyproheptadine; Female; Gastric Mucosa; Male; Peptic Ulcer Hemorrhage; Rats; Serotonin; Sto | 1989 |
[Blood viscosity indicators in patients with gastric and duodenal diseases].
Topics: Adolescent; Adult; Blood Viscosity; Chronic Disease; Cimetidine; Cyproheptadine; Duodenal Ulcer; Fem | 1985 |