Page last updated: 2024-10-25

cyproheptadine and Sneezing

cyproheptadine has been researched along with Sneezing in 5 studies

Cyproheptadine: A serotonin antagonist and a histamine H1 blocker used as antipruritic, appetite stimulant, antiallergic, and for the post-gastrectomy dumping syndrome, etc.
cyproheptadine : The product resulting from the formal oxidative coupling of position 5 of 5H-dibenzo[a,d]cycloheptene with position 4 of 1-methylpiperidine resulting in the formation of a double bond between the two fragments. It is a sedating antihistamine with antimuscarinic and calcium-channel blocking actions. It is used (particularly as the hydrochloride sesquihydrate) for the relief of allergic conditions including rhinitis, conjunctivitis due to inhalant allergens and foods, urticaria and angioedema, and in pruritic skin disorders. Unlike other antihistamines, it is also a seratonin receptor antagonist, making it useful in conditions such as vascular headache and anorexia.

Sneezing: The sudden, forceful, involuntary expulsion of air from the NOSE and MOUTH caused by irritation to the MUCOUS MEMBRANES of the upper RESPIRATORY TRACT.

Research Excerpts

ExcerptRelevanceReference
"Subjective single and composite nasal and nonnasal symptoms were consistently less severe with rupatadine use than with placebo use starting from the first evaluation at 15 minutes to the end of the 6-hour Vienna Challenge Chamber challenge, with the most significant effects seen for nasal rhinorrhea, nasal itching, sneezing attacks, and total nasal symptoms (P < ."5.12Effects of rupatadine vs placebo on allergen-induced symptoms in patients exposed to aeroallergens in the Vienna Challenge Chamber. ( Arnáiz, E; Horak, F; Izquierdo, I; Leuratti, C; Pérez, I; Stuebner, P; Zieglmayer, R, 2006)
"BW A868C was more potent in inhibiting the nasal symptoms than ramatroban."1.34Interactive effect of histamine and prostaglandin D2 on nasal allergic symptoms in rats. ( Ago, J; Inoue, T; Ishikawa, T; Kamei, C; Rahman, A, 2007)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (40.00)18.2507
2000's3 (60.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Stuebner, P1
Horak, F1
Zieglmayer, R1
Arnáiz, E1
Leuratti, C1
Pérez, I1
Izquierdo, I1
Rahman, MA1
Inoue, T2
Kamei, C2
Rahman, A1
Ago, J1
Ishikawa, T1
Naclerio, RM1
Frølund, L1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Nasal Ocular Reflexes Contribute to Eye Symptoms in Patients With Allergic Rhinitis[NCT00117832]20 participants Interventional2005-03-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

3 trials available for cyproheptadine and Sneezing

ArticleYear
Effects of rupatadine vs placebo on allergen-induced symptoms in patients exposed to aeroallergens in the Vienna Challenge Chamber.
    Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2006, Volume: 96, Issue:1

    Topics: Adolescent; Adult; Antigens, Plant; Cross-Over Studies; Cyproheptadine; Dactylis; Double-Blind Metho

2006
The effect of antihistamines on the immediate allergic response: a comparative review.
    Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 1993, Volume: 108, Issue:6

    Topics: Capillary Permeability; Cetirizine; Cyproheptadine; Diphenhydramine; Double-Blind Method; Histamine

1993
Efficacy of an oral antihistamine, loratadine, as compared with a nasal steroid spray, beclomethasone dipropionate, in seasonal allergic rhinitis.
    Clinical otolaryngology and allied sciences, 1991, Volume: 16, Issue:6

    Topics: Administration, Intranasal; Administration, Oral; Adult; Aged; Beclomethasone; Cyproheptadine; Doubl

1991

Other Studies

2 other studies available for cyproheptadine and Sneezing

ArticleYear
Role of substance P in allergic nasal symptoms in rats.
    European journal of pharmacology, 2006, Feb-17, Volume: 532, Issue:1-2

    Topics: Animals; Antigens; Cyproheptadine; Dibenzazepines; Dibenzoxepins; Dose-Response Relationship, Drug;

2006
Interactive effect of histamine and prostaglandin D2 on nasal allergic symptoms in rats.
    European journal of pharmacology, 2007, Jan-12, Volume: 554, Issue:2-3

    Topics: Administration, Intranasal; Administration, Oral; Animals; Carbazoles; Chlorpheniramine; Cyproheptad

2007