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cyproheptadine and Sleep Wake Disorders

cyproheptadine has been researched along with Sleep Wake Disorders in 8 studies

Cyproheptadine: A serotonin antagonist and a histamine H1 blocker used as antipruritic, appetite stimulant, antiallergic, and for the post-gastrectomy dumping syndrome, etc.
cyproheptadine : The product resulting from the formal oxidative coupling of position 5 of 5H-dibenzo[a,d]cycloheptene with position 4 of 1-methylpiperidine resulting in the formation of a double bond between the two fragments. It is a sedating antihistamine with antimuscarinic and calcium-channel blocking actions. It is used (particularly as the hydrochloride sesquihydrate) for the relief of allergic conditions including rhinitis, conjunctivitis due to inhalant allergens and foods, urticaria and angioedema, and in pruritic skin disorders. Unlike other antihistamines, it is also a seratonin receptor antagonist, making it useful in conditions such as vascular headache and anorexia.

Sleep Wake Disorders: Abnormal sleep-wake schedule or pattern associated with the CIRCADIAN RHYTHM which affect the length, timing, and/or rigidity of the sleep-wake cycle relative to the day-night cycle.

Research Excerpts

ExcerptRelevanceReference
" This research evaluates the preventive effects of cyproheptadine on sleeping and appetite disorders induced by methylphenidate in ADHD children."9.30Preventive effect of cyproheptadine on sleep and appetite disorders induced by methylphenidate: an exploratory randomised, double-blinded, placebo-controlled clinical trial. ( Elyasi, S; Kadkhoda Mezerji, F; Mohammadpour, AH; Moharreri, F, 2019)
" This research evaluates the preventive effects of cyproheptadine on sleeping and appetite disorders induced by methylphenidate in ADHD children."5.30Preventive effect of cyproheptadine on sleep and appetite disorders induced by methylphenidate: an exploratory randomised, double-blinded, placebo-controlled clinical trial. ( Elyasi, S; Kadkhoda Mezerji, F; Mohammadpour, AH; Moharreri, F, 2019)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19901 (12.50)18.7374
1990's2 (25.00)18.2507
2000's4 (50.00)29.6817
2010's1 (12.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kadkhoda Mezerji, F1
Moharreri, F1
Mohammadpour, AH1
Elyasi, S1
Cortese, S1
Lecendreux, M1
Mouren, MC1
Konofal, E1
Tokunaga, S1
Takeda, Y1
Shinomiya, K1
Hirase, M1
Kamei, C1
Gupta, S1
Austin, R1
Cali, LA1
Bhatara, V1
Rijnders, RJ1
Laman, DM1
Van Diujn, H1
Jacobs-Rebhun, S1
Schnurr, PP1
Friedman, MJ1
Peck, R1
Brophy, M1
Fuller, D1
Brophy, MH1
Harsch, HH1

Trials

2 trials available for cyproheptadine and Sleep Wake Disorders

ArticleYear
Preventive effect of cyproheptadine on sleep and appetite disorders induced by methylphenidate: an exploratory randomised, double-blinded, placebo-controlled clinical trial.
    International journal of psychiatry in clinical practice, 2019, Volume: 23, Issue:1

    Topics: Attention Deficit Disorder with Hyperactivity; Central Nervous System Stimulants; Child; Child, Pres

2019
Posttraumatic stress disorder and sleep difficulty.
    The American journal of psychiatry, 2000, Volume: 157, Issue:9

    Topics: Cyproheptadine; Double-Blind Method; Humans; Male; Patient Selection; Placebos; Recurrence; Research

2000

Other Studies

6 other studies available for cyproheptadine and Sleep Wake Disorders

ArticleYear
ADHD and insomnia.
    Journal of the American Academy of Child and Adolescent Psychiatry, 2006, Volume: 45, Issue:4

    Topics: Antidepressive Agents; Attention Deficit Disorder with Hyperactivity; Central Nervous System Stimula

2006
Effects of some H1-antagonists on the sleep-wake cycle in sleep-disturbed rats.
    Journal of pharmacological sciences, 2007, Volume: 103, Issue:2

    Topics: Animals; Chlorpheniramine; Cyproheptadine; Diphenhydramine; Dose-Response Relationship, Drug; Electr

2007
Nightmares treated with cyproheptadine.
    Journal of the American Academy of Child and Adolescent Psychiatry, 1998, Volume: 37, Issue:6

    Topics: Child; Cyproheptadine; Dreams; Humans; Male; Serotonin Antagonists; Sleep Wake Disorders; Stress Dis

1998
Cyproheptadine for posttraumatic nightmares.
    The American journal of psychiatry, 2000, Volume: 157, Issue:9

    Topics: Adult; Cyproheptadine; Dreams; Electroencephalography; Female; Humans; Polysomnography; Rape; Second

2000
Cyproheptadine for combat nightmares in post-traumatic stress disorder and dream anxiety disorder.
    Military medicine, 1991, Volume: 156, Issue:2

    Topics: Adult; Aged; Antidepressive Agents; Anxiety Disorders; Cyproheptadine; Drug Therapy, Combination; Hu

1991
Cyproheptadine for recurrent nightmares.
    The American journal of psychiatry, 1986, Volume: 143, Issue:11

    Topics: Adult; Anxiety Disorders; Cyproheptadine; Dreams; Female; Humans; Male; Middle Aged; Recurrence; Sle

1986