Page last updated: 2024-10-25

cyproheptadine and Rhinitis, Allergic, Seasonal

cyproheptadine has been researched along with Rhinitis, Allergic, Seasonal in 55 studies

Cyproheptadine: A serotonin antagonist and a histamine H1 blocker used as antipruritic, appetite stimulant, antiallergic, and for the post-gastrectomy dumping syndrome, etc.
cyproheptadine : The product resulting from the formal oxidative coupling of position 5 of 5H-dibenzo[a,d]cycloheptene with position 4 of 1-methylpiperidine resulting in the formation of a double bond between the two fragments. It is a sedating antihistamine with antimuscarinic and calcium-channel blocking actions. It is used (particularly as the hydrochloride sesquihydrate) for the relief of allergic conditions including rhinitis, conjunctivitis due to inhalant allergens and foods, urticaria and angioedema, and in pruritic skin disorders. Unlike other antihistamines, it is also a seratonin receptor antagonist, making it useful in conditions such as vascular headache and anorexia.

Rhinitis, Allergic, Seasonal: Allergic rhinitis that occurs at the same time every year. It is characterized by acute CONJUNCTIVITIS with lacrimation and ITCHING, and regarded as an allergic condition triggered by specific ALLERGENS.

Research Excerpts

ExcerptRelevanceReference
" One hundred and seven hay fever patients, sensitive to birch pollen, were randomized into three parallel groups receiving loratadine 40 mg once daily, clemastine 1 mg twice daily, or placebo during the birch pollen season."9.06Treatment of hay fever with loratadine--a new non-sedating antihistamine. ( Irander, K; Odkvist, LM; Ohlander, B, 1990)
"In this double-blind study, 65 patients with hay fever were treated for 14 days with either loratadine 10 mg once daily, astemizole 10 mg once daily, or placebo."9.06Double-blind comparison of loratadine (SCH 29851), astemizole, and placebo in hay fever with special regard to onset of action. ( Oei, HD, 1988)
"The prevalence of allergic rhinitis has exhibited an upward trend, and diabetes is a common endocrine metabolic disorder."5.72Efficacy and Safety of Rupatadine Fumarate Combined with Acupoint Application in Allergic Rhinitis Complicated with Diabetes. ( Chen, X; Jiang, P; Liu, Y; Shi, J; Zhang, W, 2022)
"To measure the reduction in nasal obstruction using acoustic rhinometry in patients with allergic rhinitis treated with rupatadine."5.14Reduction of nasal volume after allergen-induced rhinitis in patients treated with rupatadine: a randomized, cross-over, double-blind, placebo-controlled study. ( Bartrá, J; Izquierdo, I; Mullol, J; Muñoz-Cano, R; Picado, C; Serrano, C; Valero, A, 2009)
"Subjective single and composite nasal and nonnasal symptoms were consistently less severe with rupatadine use than with placebo use starting from the first evaluation at 15 minutes to the end of the 6-hour Vienna Challenge Chamber challenge, with the most significant effects seen for nasal rhinorrhea, nasal itching, sneezing attacks, and total nasal symptoms (P < ."5.12Effects of rupatadine vs placebo on allergen-induced symptoms in patients exposed to aeroallergens in the Vienna Challenge Chamber. ( Arnáiz, E; Horak, F; Izquierdo, I; Leuratti, C; Pérez, I; Stuebner, P; Zieglmayer, R, 2006)
" One hundred and seven hay fever patients, sensitive to birch pollen, were randomized into three parallel groups receiving loratadine 40 mg once daily, clemastine 1 mg twice daily, or placebo during the birch pollen season."5.06Treatment of hay fever with loratadine--a new non-sedating antihistamine. ( Irander, K; Odkvist, LM; Ohlander, B, 1990)
"The efficacy and safety of loratadine, 40 mg once daily, were compared with terfenadine, 60 mg twice daily, and placebo in controlling symptoms of ragweed hay fever."5.06Comparison of the efficacy and safety of loratadine, terfenadine, and placebo in the treatment of seasonal allergic rhinitis. ( Bedard, P; Del Carpio, J; Gutkowski, A; Hebert, J; Prevost, M; Schulz, J; Turenne, Y; Yeadon, C, 1988)
"In this double-blind study, 65 patients with hay fever were treated for 14 days with either loratadine 10 mg once daily, astemizole 10 mg once daily, or placebo."5.06Double-blind comparison of loratadine (SCH 29851), astemizole, and placebo in hay fever with special regard to onset of action. ( Oei, HD, 1988)
" Rupatadine, a molecule with intense antihistaminic activity and with antagonist PAF effects through its interaction with specific receptors, is indicated for the treatment of intermittent or persistent allergic rhinitis and urticaria."4.89Efficacy and safety of rupatadine for allergic rhino-conjunctivitis: a systematic review of randomized, double-blind, placebo-controlled studies with meta-analysis. ( Canonica, GW; Compalati, E, 2013)
" The rates of adverse events were 6."2.90Efficacy and safety of rupatadine in Japanese patients with seasonal allergic rhinitis: A double-blind, randomized, multicenter, placebo-controlled clinical trial. ( Aoki, H; Okubo, K; Suzuki, T; Tanaka, A, 2019)
" Incidence of adverse effects was less in the rupatadine group compared with the levocetirizine group."2.75Rupatadine and levocetirizine for seasonal allergic rhinitis: a comparative study of efficacy and safety. ( Allala, U; Jaida, J; Maiti, R; Palani, A; Rahman, J, 2010)
" All treatments were well tolerated and no serious adverse events were recorded."2.71A randomized, double-blind, parallel-group study, comparing the efficacy and safety of rupatadine (20 and 10 mg), a new PAF and H1 receptor-specific histamine antagonist, to loratadine 10 mg in the treatment of seasonal allergic rhinitis. ( Dumur, JP; Izquierdo, I; Pérez, I; Saint-Martin, F, 2004)
"Rupatadine is a new second generation H(1)-antihistamine with once-daily dosing that may provide better control of symptoms than the currently used H(1)-receptor blockers because of its dual pharmacological profile (anti-PAF and anti-H(1))."2.71Rupatadine 10 mg and ebastine 10 mg in seasonal allergic rhinitis: a comparison study. ( Castillo, JA; De Molina, M; Guadaño, EM; Meseguer, J; Picado, C; Serra-Batlles, J; Valero, A, 2004)
"Terfenadine was more effective than both loratadine (P less than ."2.67Suppression of epicutaneous reactivity by terfenadine and loratadine. ( Small, P, 1992)
"Thus loratadine is an effective and safe antihistamine when given once daily for the symptomatic relief of seasonal allergic rhinitis."2.67Comparative effects of loratadine and azatadine in the treatment of seasonal allergic rhinitis. ( Katelaris, C, 1990)
"Pretreatment with azatadine significantly suppressed the number of sneezes following antigen challenge and inhibited the associated elevations in histamine, kinins, and enzyme(s) hydrolyzing the artificial substrate N-alpha-tosyl-L-arginine-methyl-ester in nasal secretions, whereas placebo was inactive."2.66Demonstration of inhibition of mediator release from human mast cells by azatadine base. In vivo and in vitro evaluation. ( Kagey-Sobotka, A; Lichtenstein, LM; Naclerio, RM; Nimmagadda, I; Norman, PS; Proud, D; Togias, AG; Warner, J, 1986)
" Loratadine appears to be a simple, effective and safe therapy for seasonal allergic rhinitis."2.66Efficacy and safety of loratadine suspension in the treatment of children with allergic rhinitis. ( Andreoli, A; Boner, AL; Marchesi, E; Miglioranzi, P; Richelli, C, 1989)
"Loratadine was particularly effective compared with placebo in relieving nasal discharge, sneezing, and itching/burning eyes."2.66Efficacy and safety of loratadine (10 mg once daily), terfenadine (60 mg twice daily), and placebo in the treatment of seasonal allergic rhinitis. ( Bedard, PM; Del Carpio, J; Gutkowski, A; Hebert, J; Kabbash, L; Nedilski, M; Prevost, M; Schulz, J; Turenne, Y, 1989)
" Loratadine was found to be both safe and efficacious."2.66Safety and efficacy of loratadine (Sch-29851): a new non-sedating antihistamine in seasonal allergic rhinitis. ( Bergner, A; Connell, JT; Dockhorn, RJ; Falliers, CJ; Grabiec, SV; Shellenberger, MK; Weiler, JM, 1987)
"Loratadine was found to be significantly superior to placebo after 3 days of treatment, whereas a significant improvement was only observed after 7 days in patients treated with mequitazine."2.66Double-blind placebo-controlled study of loratadine, mequitazine, and placebo in the symptomatic treatment of seasonal allergic rhinitis. ( Bousquet, J; Lherminier, M; Michel, FB; Montes, F; Schwab, D; Skassa-Brociek, W; Verdier, M, 1988)
"Two patient groups were treated, one with seasonal allergic rhinitis for two days during the peak of the ragweed season, and another with perennial allergic rhinitis for an extended six-week period."2.65Controlled comparison of anew antihistamine-decongestant combination to its individual components. ( Falliers, CJ; Redding, MA, 1980)
" Eighty percent of patients had symptomatic relief with a twice daily dosage of 2 mg."2.65Azatadine maleate (Zadine): evaluation in the management of allergic rhinitis. ( Hillas, JL; Somerfield, SD; Wilson, JD, 1981)
"Rupatadine is a once-daily non-sedative, selective, long-acting H1 anti-histamine with antagonistic PAF effects through its interaction with specific receptors."2.45Pharmacological profile, efficacy and safety of rupatadine in allergic rhinitis. ( Katiyar, S; Prakash, S, 2009)
"Rupatadine is a once-daily, non-sedating, selective and long-acting new drug with a strong antagonist activity towards both histamine H(1) receptors and platelet-activating factor receptors."2.43Rupatadine: pharmacological profile and its use in the treatment of allergic disorders. ( Picado, C, 2006)
"Rupatadine is a new agent for the management of diseases with allergic inflammatory conditions, such as seasonal and perennial rhinitis."2.42Rupatadine: a new selective histamine H1 receptor and platelet-activating factor (PAF) antagonist. A review of pharmacological profile and clinical management of allergic rhinitis. ( García-Rafanell, J; Izquierdo, I; Merlos, M, 2003)
"In this review of the current treatment of seasonal allergic rhinitis, the clinical studies that compare these four new second-generation H1-receptor antagonists are discussed."2.38H1-receptor antagonist treatment of seasonal allergic rhinitis. ( Kaiser, HB, 1990)
"Loratadine is a long acting antihistamine which has a high selectivity for peripheral histamine H1-receptors and lacks the central nervous system depressant effects often associated with some of the older antihistamines."2.38Loratadine. A preliminary review of its pharmacodynamic properties and therapeutic efficacy. ( Clissold, SP; Goa, KL; Sorkin, EM, 1989)
"The prevalence of allergic rhinitis has exhibited an upward trend, and diabetes is a common endocrine metabolic disorder."1.72Efficacy and Safety of Rupatadine Fumarate Combined with Acupoint Application in Allergic Rhinitis Complicated with Diabetes. ( Chen, X; Jiang, P; Liu, Y; Shi, J; Zhang, W, 2022)

Research

Studies (55)

TimeframeStudies, this research(%)All Research%
pre-199026 (47.27)18.7374
1990's10 (18.18)18.2507
2000's10 (18.18)29.6817
2010's8 (14.55)24.3611
2020's1 (1.82)2.80

Authors

AuthorsStudies
Liu, Y1
Jiang, P1
Chen, X1
Zhang, W1
Shi, J1
Okubo, K1
Suzuki, T1
Tanaka, A1
Aoki, H1
Compalati, E2
Canonica, GW2
Berger, VW1
Gudehithlu, SK1
Katiyar, S1
Prakash, S1
LEVIN, L1
KELLY, JF1
SCHWARTZ, E1
Valero, A3
Serrano, C1
Bartrá, J2
Izquierdo, I7
Muñoz-Cano, R1
Mullol, J3
Picado, C4
Maiti, R1
Rahman, J1
Jaida, J1
Allala, U1
Palani, A1
Metz, M1
Maurer, M2
Giralt, J2
del Cuvillo, A1
Potter, P1
Maspero, JF1
Vermeulen, J1
Barkai, L1
Németh, I1
Baillieau, RA1
Garde, JM1
Doménech, A1
Nieto, A1
Merlos, M1
García-Rafanell, J1
JENSEN, K1
SMELLIE, H1
FRY, L1
Saint-Martin, F1
Dumur, JP1
Pérez, I3
Guadaño, EM1
Serra-Batlles, J1
Meseguer, J1
Castillo, JA1
De Molina, M2
Martínez-Cócera, C1
Martí-Guadaño, E2
Pola, J1
Conde, J1
Borja, J1
Arnaiz, E2
Stuebner, P1
Horak, F2
Zieglmayer, R1
Leuratti, C1
Keam, SJ1
Plosker, GL1
Bousquet, J3
Bachert, C1
Canonica, WG1
Gimenez-Arnau, A1
Kowalski, ML1
Scadding, G1
Van Cauwenberge, P1
Tarasido, JC1
Zubizaretta, J1
Falliers, CJ2
Redding, MA1
Wilson, JD1
Hillas, JL1
Somerfield, SD1
Naclerio, RM2
Connell, JT2
Tarnick, M1
Kolbas, V1
Pansini, K1
Small, P1
Boner, AL2
Richelli, C2
Castellani, C1
Marchesi, E2
Andreoli, A2
Frølund, L3
Andersson, M1
Nolte, H1
Baumgarten, C1
Pipkorn, U1
Kaiser, HB1
Massey, WA1
Lichtenstein, LM2
Katelaris, C1
Irander, K1
Odkvist, LM1
Ohlander, B1
Togias, AG1
Warner, J1
Proud, D1
Kagey-Sobotka, A1
Nimmagadda, I1
Norman, PS1
Lebel, B1
Chanal, I1
Morel, A1
Michel, FB2
Storms, WW1
Bodman, SF1
Nathan, RA1
Chervinsky, P1
Banov, CH1
Dockhorn, RJ2
Jarmoszuk, I1
Zeitz, HJ1
McGeady, SJ1
Pinnas, JL1
Clissold, SP1
Sorkin, EM1
Goa, KL1
Grossman, J1
Bronsky, EA1
Lanier, BQ1
Linzmayer, MI1
Moss, BA1
Schenkel, EJ1
Selner, JC1
Miglioranzi, P1
Simons, FE1
Del Carpio, J2
Kabbash, L1
Turenne, Y2
Prevost, M2
Hebert, J2
Bedard, PM1
Nedilski, M1
Gutkowski, A2
Schulz, J2
Bindslev-Jensen, C1
Svendsen, UG1
Bruttmann, G1
Pedrali, P1
Weeke, B1
Wolff, HH1
Christophers, E1
Bedard, P1
Yeadon, C1
Oei, HD1
Bergner, A1
Grabiec, SV1
Weiler, JM1
Shellenberger, MK1
Skassa-Brociek, W1
Montes, F1
Verdier, M1
Schwab, D1
Lherminier, M1
Schultze-Wernighaus, G1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Nasal Ocular Reflexes Contribute to Eye Symptoms in Patients With Allergic Rhinitis[NCT00117832]20 participants Interventional2005-03-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

11 reviews available for cyproheptadine and Rhinitis, Allergic, Seasonal

ArticleYear
Efficacy and safety of rupatadine for allergic rhino-conjunctivitis: a systematic review of randomized, double-blind, placebo-controlled studies with meta-analysis.
    Current medical research and opinion, 2013, Volume: 29, Issue:11

    Topics: Conjunctivitis, Allergic; Cyproheptadine; Histamine Antagonists; Humans; Platelet Activating Factor;

2013
Pharmacological profile, efficacy and safety of rupatadine in allergic rhinitis.
    Primary care respiratory journal : journal of the General Practice Airways Group, 2009, Volume: 18, Issue:2

    Topics: Adolescent; Adult; Cyproheptadine; Histamine H1 Antagonists, Non-Sedating; Humans; Randomized Contro

2009
Rupatadine for the treatment of allergic rhinitis and urticaria.
    Expert review of clinical immunology, 2011, Volume: 7, Issue:1

    Topics: Anti-Allergic Agents; Chronic Disease; Cyproheptadine; Histamine H1 Antagonists; Humans; Platelet Ac

2011
Rupatadine: a new selective histamine H1 receptor and platelet-activating factor (PAF) antagonist. A review of pharmacological profile and clinical management of allergic rhinitis.
    Drugs of today (Barcelona, Spain : 1998), 2003, Volume: 39, Issue:6

    Topics: Animals; Clinical Trials as Topic; Cyproheptadine; Dose-Response Relationship, Drug; Histamine H1 An

2003
Rupatadine: pharmacological profile and its use in the treatment of allergic disorders.
    Expert opinion on pharmacotherapy, 2006, Volume: 7, Issue:14

    Topics: Adolescent; Adult; Animals; Cyproheptadine; Histamine H1 Antagonists; Humans; Psychomotor Performanc

2006
Rupatadine: a review of its use in the management of allergic disorders.
    Drugs, 2007, Volume: 67, Issue:3

    Topics: Adolescent; Adult; Aged; Animals; Anti-Allergic Agents; Cyproheptadine; Drug Interactions; Humans; H

2007
Rupatadine in allergic rhinitis and chronic urticaria.
    Allergy, 2008, Volume: 63 Suppl 87

    Topics: Adolescent; Animals; Anti-Allergic Agents; Child; Chronic Disease; Clinical Trials as Topic; Cyprohe

2008
H1-receptor antagonist treatment of seasonal allergic rhinitis.
    The Journal of allergy and clinical immunology, 1990, Volume: 86, Issue:6 Pt 2

    Topics: Astemizole; Benzhydryl Compounds; Benzimidazoles; Cetirizine; Chlorpheniramine; Clemastine; Cyprohep

1990
The effects of antihistamines beyond H1 antagonism in allergic inflammation.
    The Journal of allergy and clinical immunology, 1990, Volume: 86, Issue:6 Pt 2

    Topics: Benzhydryl Compounds; Cetirizine; Cyproheptadine; Dermatitis, Atopic; Histamine H1 Antagonists; Hist

1990
Three new non-sedative antihistamines: worth keeping an eye open for.
    Drug and therapeutics bulletin, 1990, May-14, Volume: 28, Issue:10

    Topics: Cetirizine; Cyproheptadine; Histamine H1 Antagonists; Humans; Hydroxyzine; Loratadine; Rhinitis, All

1990
Loratadine. A preliminary review of its pharmacodynamic properties and therapeutic efficacy.
    Drugs, 1989, Volume: 37, Issue:1

    Topics: Animals; Common Cold; Cyproheptadine; Female; Humans; Loratadine; Male; Rhinitis, Allergic, Perennia

1989

Trials

35 trials available for cyproheptadine and Rhinitis, Allergic, Seasonal

ArticleYear
Efficacy and safety of rupatadine in Japanese patients with seasonal allergic rhinitis: A double-blind, randomized, multicenter, placebo-controlled clinical trial.
    Allergology international : official journal of the Japanese Society of Allergology, 2019, Volume: 68, Issue:2

    Topics: Adolescent; Adult; Anti-Allergic Agents; Child; Cyproheptadine; Double-Blind Method; Female; Humans;

2019
Reduction of nasal volume after allergen-induced rhinitis in patients treated with rupatadine: a randomized, cross-over, double-blind, placebo-controlled study.
    Journal of investigational allergology & clinical immunology, 2009, Volume: 19, Issue:6

    Topics: Administration, Intranasal; Adolescent; Adult; Anti-Allergic Agents; Cyproheptadine; Disease Progres

2009
Rupatadine and levocetirizine for seasonal allergic rhinitis: a comparative study of efficacy and safety.
    Archives of otolaryngology--head & neck surgery, 2010, Volume: 136, Issue:8

    Topics: Adolescent; Adult; Cetirizine; Conjunctivitis, Allergic; Cyproheptadine; Eosinophils; Female; Histam

2010
Rupatadine improves nasal symptoms, quality of life (ESPRINT-15) and severity in a subanalysis of a cohort of Spanish allergic rhinitis patients.
    Journal of investigational allergology & clinical immunology, 2011, Volume: 21, Issue:3

    Topics: Administration, Intranasal; Adrenal Cortex Hormones; Adult; Cyproheptadine; Female; Histamine H1 Ant

2011
Rupatadine oral solution in children with persistent allergic rhinitis: A randomized, double-blind, placebo-controlled study.
    Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology, 2013, Volume: 24, Issue:2

    Topics: Administration, Oral; Analysis of Variance; Anti-Allergic Agents; Argentina; Child; Cyproheptadine;

2013
A randomized, double-blind, parallel-group study, comparing the efficacy and safety of rupatadine (20 and 10 mg), a new PAF and H1 receptor-specific histamine antagonist, to loratadine 10 mg in the treatment of seasonal allergic rhinitis.
    Journal of investigational allergology & clinical immunology, 2004, Volume: 14, Issue:1

    Topics: Administration, Oral; Adolescent; Adult; Aged; Child; Cross-Over Studies; Cyproheptadine; Dose-Respo

2004
Rupatadine 10 mg and ebastine 10 mg in seasonal allergic rhinitis: a comparison study.
    Allergy, 2004, Volume: 59, Issue:7

    Topics: Adolescent; Adult; Analysis of Variance; Anti-Allergic Agents; Butyrophenones; Cyproheptadine; Doubl

2004
Rupatadine 10 mg and cetirizine 10 mg in seasonal allergic rhinitis: a randomised, double-blind parallel study.
    Journal of investigational allergology & clinical immunology, 2005, Volume: 15, Issue:1

    Topics: Adolescent; Adult; Aged; Anti-Allergic Agents; Cetirizine; Child; Cyproheptadine; Double-Blind Metho

2005
Effects of rupatadine vs placebo on allergen-induced symptoms in patients exposed to aeroallergens in the Vienna Challenge Chamber.
    Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2006, Volume: 96, Issue:1

    Topics: Adolescent; Adult; Antigens, Plant; Cross-Over Studies; Cyproheptadine; Dactylis; Double-Blind Metho

2006
Azatadine maleate/pseudoephedrine sulfate repetabs versus placebo in the treatment of severe seasonal allergic rhinitis.
    The Journal of international medical research, 1980, Volume: 8, Issue:6

    Topics: Adolescent; Adult; Cyproheptadine; Double-Blind Method; Drug Combinations; Ephedrine; Female; Histam

1980
Azatadine maleate/pseudoephedrine sulfate repetabs versus placebo in the treatment of severe perennial allergic rhinitis.
    The Journal of international medical research, 1980, Volume: 8, Issue:6

    Topics: Adolescent; Adult; Aged; Cyproheptadine; Delayed-Action Preparations; Double-Blind Method; Drug Comb

1980
Controlled comparison of anew antihistamine-decongestant combination to its individual components.
    Annals of allergy, 1980, Volume: 45, Issue:2

    Topics: Cyproheptadine; Drug Therapy, Combination; Ephedrine; Female; Histamine H1 Antagonists; Humans; Male

1980
Azatadine maleate (Zadine): evaluation in the management of allergic rhinitis.
    The New Zealand medical journal, 1981, Aug-12, Volume: 94, Issue:689

    Topics: Adolescent; Adult; Child; Clinical Trials as Topic; Cyproheptadine; Double-Blind Method; Female; Hum

1981
The effect of antihistamines on the immediate allergic response: a comparative review.
    Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 1993, Volume: 108, Issue:6

    Topics: Capillary Permeability; Cetirizine; Cyproheptadine; Diphenhydramine; Double-Blind Method; Histamine

1993
Azatadine (optimine)--a new antihistamine.
    The Medical letter on drugs and therapeutics, 1977, Sep-23, Volume: 19, Issue:19

    Topics: Clinical Trials as Topic; Cyproheptadine; Histamine H1 Antagonists; Humans; Placebos; Rhinitis, Alle

1977
A novel method to assess antihistamine and decongestant efficacy.
    Annals of allergy, 1979, Volume: 42, Issue:5

    Topics: Clinical Trials as Topic; Cyproheptadine; Double-Blind Method; Ephedrine; Female; Histamine H1 Antag

1979
Suppression of epicutaneous reactivity by terfenadine and loratadine.
    Annals of allergy, 1992, Volume: 68, Issue:1

    Topics: Cyproheptadine; Double-Blind Method; Female; Histamine H1 Antagonists; Humans; Hypersensitivity; Lor

1992
Comparison of the effects of loratadine and astemizole in the treatment of children with seasonal allergic rhinoconjunctivitis.
    Allergy, 1992, Volume: 47, Issue:2 Pt 1

    Topics: Adolescent; Astemizole; Child; Conjunctivitis, Allergic; Cyproheptadine; Female; Histamine Antagonis

1992
Efficacy of an oral antihistamine, loratadine, as compared with a nasal steroid spray, beclomethasone dipropionate, in seasonal allergic rhinitis.
    Clinical otolaryngology and allied sciences, 1991, Volume: 16, Issue:6

    Topics: Administration, Intranasal; Administration, Oral; Adult; Aged; Beclomethasone; Cyproheptadine; Doubl

1991
Suppressive effect of loratadine on allergen-induced histamine release in the nose.
    Allergy, 1991, Volume: 46, Issue:7

    Topics: Adolescent; Adult; Allergens; Cyproheptadine; Double-Blind Method; Female; Histamine H1 Antagonists;

1991
The effects of antihistamines beyond H1 antagonism in allergic inflammation.
    The Journal of allergy and clinical immunology, 1990, Volume: 86, Issue:6 Pt 2

    Topics: Benzhydryl Compounds; Cetirizine; Cyproheptadine; Dermatitis, Atopic; Histamine H1 Antagonists; Hist

1990
Comparative effects of loratadine and azatadine in the treatment of seasonal allergic rhinitis.
    Asian Pacific journal of allergy and immunology, 1990, Volume: 8, Issue:2

    Topics: Adolescent; Adult; Aged; Cyproheptadine; Double-Blind Method; Female; Histamine Antagonists; Histami

1990
Treatment of hay fever with loratadine--a new non-sedating antihistamine.
    Allergy, 1990, Volume: 45, Issue:2

    Topics: Clemastine; Cyproheptadine; Double-Blind Method; Drug Evaluation; Female; Histamine Antagonists; Hum

1990
Demonstration of inhibition of mediator release from human mast cells by azatadine base. In vivo and in vitro evaluation.
    JAMA, 1986, Jan-10, Volume: 255, Issue:2

    Topics: Adolescent; Adult; Clinical Trials as Topic; Cyproheptadine; Double-Blind Method; Female; Histamine

1986
Antiallergic activity of H1-receptor antagonists assessed by nasal challenge.
    The Journal of allergy and clinical immunology, 1988, Volume: 82, Issue:5 Pt 1

    Topics: Adult; Benzhydryl Compounds; Cyproheptadine; Double-Blind Method; Histamine H1 Antagonists; Histamin

1988
SCH 434: a new antihistamine/decongestant for seasonal allergic rhinitis.
    The Journal of allergy and clinical immunology, 1989, Volume: 83, Issue:6

    Topics: Adolescent; Adult; Child; Cyproheptadine; Delayed-Action Preparations; Double-Blind Method; Drug Com

1989
Loratadine-pseudoephedrine combination versus placebo in patients with seasonal allergic rhinitis.
    Annals of allergy, 1989, Volume: 63, Issue:4

    Topics: Adolescent; Adult; Aged; Child; Cyproheptadine; Drug Combinations; Ephedrine; Female; Histamine Anta

1989
Efficacy and safety of loratadine suspension in the treatment of children with allergic rhinitis.
    Allergy, 1989, Volume: 44, Issue:6

    Topics: Administration, Oral; Child; Child, Preschool; Chlorpheniramine; Cyproheptadine; Double-Blind Method

1989
Efficacy and safety of loratadine (10 mg once daily), terfenadine (60 mg twice daily), and placebo in the treatment of seasonal allergic rhinitis.
    The Journal of allergy and clinical immunology, 1989, Volume: 84, Issue:5 Pt 1

    Topics: Adolescent; Adult; Benzhydryl Compounds; Cyproheptadine; Double-Blind Method; Drug Administration Sc

1989
A multicentric study of loratadine, terfenadine and placebo in patients with seasonal allergic rhinitis.
    Arzneimittel-Forschung, 1988, Volume: 38, Issue:1

    Topics: Adolescent; Adult; Aged; Benzhydryl Compounds; Child; Clinical Trials as Topic; Cyproheptadine; Doub

1988
Comparison of the efficacy and safety of loratadine, terfenadine, and placebo in the treatment of seasonal allergic rhinitis.
    The Journal of allergy and clinical immunology, 1988, Volume: 81, Issue:5 Pt 1

    Topics: Adolescent; Adult; Benzhydryl Compounds; Clinical Trials as Topic; Cyproheptadine; Double-Blind Meth

1988
Double-blind comparison of loratadine (SCH 29851), astemizole, and placebo in hay fever with special regard to onset of action.
    Annals of allergy, 1988, Volume: 61, Issue:6

    Topics: Adolescent; Adult; Astemizole; Benzimidazoles; Clinical Trials as Topic; Cyproheptadine; Dose-Respon

1988
Safety and efficacy of loratadine (Sch-29851): a new non-sedating antihistamine in seasonal allergic rhinitis.
    Annals of allergy, 1987, Volume: 58, Issue:6

    Topics: Capsules; Clemastine; Clinical Trials as Topic; Cyproheptadine; Double-Blind Method; Histamine Antag

1987
Double-blind placebo-controlled study of loratadine, mequitazine, and placebo in the symptomatic treatment of seasonal allergic rhinitis.
    The Journal of allergy and clinical immunology, 1988, Volume: 81, Issue:4

    Topics: Adolescent; Adult; Clinical Trials as Topic; Cyproheptadine; Double-Blind Method; Female; Humans; Lo

1988
[Disodium cromoglycate in comparison with antihistaminics (loratadine) in seasonal allergic rhinitis].
    Zeitschrift fur Hautkrankheiten, 1988, Volume: 63 Suppl 4

    Topics: Adult; Clinical Trials as Topic; Cromolyn Sodium; Cyproheptadine; Histamine Antagonists; Humans; Lor

1988

Other Studies

10 other studies available for cyproheptadine and Rhinitis, Allergic, Seasonal

ArticleYear
Efficacy and Safety of Rupatadine Fumarate Combined with Acupoint Application in Allergic Rhinitis Complicated with Diabetes.
    Computational intelligence and neuroscience, 2022, Volume: 2022

    Topics: Acupuncture Points; Cyproheptadine; Diabetes Mellitus; Fumarates; Humans; Immunoglobulin E; Rhinitis

2022
Re: Compalati E, Canonica GW. Efficacy and safety of rupatadine for allergic rhino-conjunctivitis: a systematic review of randomized, double-blind, placebo-controlled studies with meta-analysis. Letter to the editor.
    Current medical research and opinion, 2013, Volume: 29, Issue:11

    Topics: Conjunctivitis, Allergic; Cyproheptadine; Histamine Antagonists; Humans; Rhinitis, Allergic, Perenni

2013
Re Letter to the editor re: Compalati E, Canonica GW. Efficacy and safety of rupatadine for allergic rhinoconjunctivitis: a systematic review of randomized, double-blind, placebo-controlled studies with meta-analysis. Curr Med Res Opin 2013 Jul 5.
    Current medical research and opinion, 2014, Volume: 30, Issue:2

    Topics: Conjunctivitis, Allergic; Cyproheptadine; Histamine Antagonists; Humans; Rhinitis, Allergic, Perenni

2014
A clinical evaluation of neo-antergan and antistine in the treatment of ragweed hay fever.
    New York state journal of medicine, 1948, Jul-01, Volume: 48, Issue:13

    Topics: Ambrosia; Antazoline; Cyproheptadine; Histamine Antagonists; Humans; Hyperthermia, Induced; Rhinitis

1948
The effect of antiserotonin (cyproheptadine) and antihistamine on cutaneous allergy.
    Acta allergologica, 1960, Volume: 15

    Topics: Anti-Allergic Agents; Cyproheptadine; Dermatitis, Atopic; Histamine H1 Antagonists; Humans; Rhinitis

1960
Comparison of an antiserotonin (cyproheptadine) and a pure antihistamine chlorpheniramine in hay fever.
    Acta allergologica, 1962, Volume: 17

    Topics: Anti-Allergic Agents; Chlorpheniramine; Cyproheptadine; Histamine H1 Antagonists; Humans; Rhinitis,

1962
[Results of the treatment in cases of cold urticaria, cold pruritus and cold rhinitis with peritol (zyproheptadinhydrochlorid) (author's transl)].
    Dermatologische Monatschrift, 1979, Volume: 165, Issue:4

    Topics: Cold Temperature; Cyproheptadine; Humans; Pruritus; Rhinitis, Allergic, Seasonal; Urticaria

1979
[Clinical testing of Idulian in hay fever in children].
    Lijecnicki vjesnik, 1975, Volume: 97, Issue:8

    Topics: Age Factors; Child; Cyproheptadine; Drug Evaluation; Humans; Rhinitis, Allergic, Seasonal

1975
Loratadine, a non-sedating H1-receptor antagonist (antihistamine)
    Annals of allergy, 1989, Volume: 63, Issue:4

    Topics: Cyproheptadine; Histamine Antagonists; Histamine H1 Antagonists; Humans; Loratadine; Rhinitis, Aller

1989
[Congestan].
    Ugeskrift for laeger, 1987, Nov-09, Volume: 149, Issue:46

    Topics: Cyproheptadine; Drug Combinations; Ephedrine; Histamine H1 Antagonists; Humans; Pseudoephedrine; Rhi

1987