cyproheptadine has been researched along with Pregnancy in 44 studies
Cyproheptadine: A serotonin antagonist and a histamine H1 blocker used as antipruritic, appetite stimulant, antiallergic, and for the post-gastrectomy dumping syndrome, etc.
cyproheptadine : The product resulting from the formal oxidative coupling of position 5 of 5H-dibenzo[a,d]cycloheptene with position 4 of 1-methylpiperidine resulting in the formation of a double bond between the two fragments. It is a sedating antihistamine with antimuscarinic and calcium-channel blocking actions. It is used (particularly as the hydrochloride sesquihydrate) for the relief of allergic conditions including rhinitis, conjunctivitis due to inhalant allergens and foods, urticaria and angioedema, and in pruritic skin disorders. Unlike other antihistamines, it is also a seratonin receptor antagonist, making it useful in conditions such as vascular headache and anorexia.
Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In three hospitals 81 female patients satisfying rigorous diagnostic criteria for anorexia nervosa were randomly allocated to one of four treatment combinations of cyproheptadine and placebo with behaviour therapy and no behaviour therapy." | 9.04 | Cyproheptadine in anorexia nervosa. ( Casper, RC; Davis, JM; Eckert, ED; Goldberg, SC; Halmi, KA, 1979) |
| "A young woman with Cushing's syndrome who had had amenorrhoea for six years was treated with cyproheptadine and became pregnant five months later." | 7.66 | Two pregnancies in a woman with Cushing's syndrome treated with cyproheptadine. Case report. ( Hartwig, W; Kasperlik-Załuska, A; Lozińska, D; Marianowski, L; Migdalska, B; Stopińska-Głuszak, U; Wilczyńska, J, 1980) |
| "We evaluated long-term treatment with the antiserotonergic agent cyproheptadine in the management of the galactorrhea-amenorrhea syndrome." | 7.66 | Cyproheptadine in the management of the galactorrhea-amenorrhea syndrome. ( Hirschowitz, J; Soler, NG; Wortsman, J, 1979) |
| "Twenty patients affected by hyperprolactinemic amenorrhea-galactorrhea have been treated with one or more of the following serotonin antagonists: metergoline, methysergide, and cyproheptadine." | 7.66 | Antiserotonin treatment of hyperprolactinemic amenorrhea: long-term follow-up with metergoline, methysergide, and cyproheptadine. ( Caccamo, A; Crosignani, PG; D'Alberton, A; Lombroso, GC; Mattei, A; Peracchi, M; Reschini, E, 1978) |
| "In three hospitals 81 female patients satisfying rigorous diagnostic criteria for anorexia nervosa were randomly allocated to one of four treatment combinations of cyproheptadine and placebo with behaviour therapy and no behaviour therapy." | 5.04 | Cyproheptadine in anorexia nervosa. ( Casper, RC; Davis, JM; Eckert, ED; Goldberg, SC; Halmi, KA, 1979) |
| " Drug treatment did not alter fetal pancreatic glucagon, pancreatic somatostatin, serum glucose, pancreas weight, or body weight." | 3.67 | Susceptibility of fetal rat endocrine pancreas to the diabetogenic action of cyproheptadine. ( Chow, SA; Fischer, LJ, 1986) |
| "A young woman with Cushing's syndrome who had had amenorrhoea for six years was treated with cyproheptadine and became pregnant five months later." | 3.66 | Two pregnancies in a woman with Cushing's syndrome treated with cyproheptadine. Case report. ( Hartwig, W; Kasperlik-Załuska, A; Lozińska, D; Marianowski, L; Migdalska, B; Stopińska-Głuszak, U; Wilczyńska, J, 1980) |
| "We evaluated long-term treatment with the antiserotonergic agent cyproheptadine in the management of the galactorrhea-amenorrhea syndrome." | 3.66 | Cyproheptadine in the management of the galactorrhea-amenorrhea syndrome. ( Hirschowitz, J; Soler, NG; Wortsman, J, 1979) |
| "Twenty patients affected by hyperprolactinemic amenorrhea-galactorrhea have been treated with one or more of the following serotonin antagonists: metergoline, methysergide, and cyproheptadine." | 3.66 | Antiserotonin treatment of hyperprolactinemic amenorrhea: long-term follow-up with metergoline, methysergide, and cyproheptadine. ( Caccamo, A; Crosignani, PG; D'Alberton, A; Lombroso, GC; Mattei, A; Peracchi, M; Reschini, E, 1978) |
| "As 5-hydroxytryptamine can interrupt pregnancy in all its stages in mice and as pregnancy can be protected from the action of 5-hydroxytryptamine by either progesterone or by prolactin only in early (days 1 to 6) but not in late pregnancy (day 14), the present experiments with two antagonists of 5-hydroxytryptamine, namely methysergide and cyproheptadine, were carried out." | 3.64 | PREVENTION BY ANTAGONISTS OF THE TOXIC ACTION OF 5-HYDROXYTRYPTAMINE ON PREGNANCY. ( POULSON, E; ROBSON, JM, 1963) |
| "Treatment with cyproheptadine, a 5HT antagonist, did not delay parturition." | 1.24 | THE 5-HYDROXYTRYPTAMINE CONTENT OF THE PLACENTA AND FOETUS DURING PREGNANCY IN MICE. ( ROBSON, JM; SENIOR, JB, 1964) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 42 (95.45) | 18.7374 |
| 1990's | 2 (4.55) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| ASTROM, A | 1 |
| SAMELIUS, U | 1 |
| HOFFMAN, DB | 1 |
| POLLACK, E | 1 |
| POULSON, E | 1 |
| ROBSON, JM | 2 |
| SENIOR, JB | 1 |
| Vigneri, R | 1 |
| Goldfine, ID | 1 |
| Board, JA | 1 |
| Fierro, RJ | 1 |
| Rodríguez González, MD | 1 |
| Lima Pérez, MT | 1 |
| Sanabria Negrín, JG | 1 |
| Moos, F | 1 |
| Richard, P | 1 |
| Chow, SA | 2 |
| Fischer, LJ | 2 |
| Thadani, PV | 1 |
| Damasio, H | 1 |
| Reiche, R | 1 |
| Frey, HH | 1 |
| Masaoka, K | 1 |
| Niibe, T | 1 |
| Kumasaka, T | 1 |
| Saito, M | 1 |
| de la Fuente, M | 1 |
| Alía, M | 1 |
| Khir, AS | 1 |
| How, J | 1 |
| Bewsher, PD | 1 |
| Walker, RF | 1 |
| Griffith, DN | 1 |
| Rose, EJ | 1 |
| Kasperlik-Załuska, A | 1 |
| Migdalska, B | 1 |
| Hartwig, W | 1 |
| Wilczyńska, J | 1 |
| Marianowski, L | 1 |
| Stopińska-Głuszak, U | 1 |
| Lozińska, D | 1 |
| Konstantinova, MM | 1 |
| Panaeva, SV | 1 |
| Podmareva, ON | 1 |
| Turpaev, TM | 1 |
| Chua, BA | 1 |
| Perks, AM | 1 |
| Corenblum, B | 1 |
| Whitaker, M | 1 |
| Goldberg, SC | 2 |
| Halmi, KA | 2 |
| Eckert, ED | 2 |
| Casper, RC | 2 |
| Davis, JM | 2 |
| Crosignani, PG | 2 |
| Lombroso, GC | 2 |
| Mattei, A | 2 |
| Caccamo, A | 2 |
| Trojsi, L | 1 |
| Wortsman, J | 1 |
| Soler, NG | 1 |
| Hirschowitz, J | 1 |
| Dolman, LI | 1 |
| Peracchi, M | 1 |
| Reschini, E | 1 |
| D'Alberton, A | 1 |
| Weinstein, D | 2 |
| Pfeifer, Y | 9 |
| Sadovsky, E | 7 |
| Polishuk, WZ | 4 |
| Sulman, FG | 8 |
| Stuart, M | 1 |
| Lazarus, L | 1 |
| Smythe, GA | 1 |
| Moore, S | 1 |
| Sara, V | 1 |
| Ornoy, A | 1 |
| Ben-Zur, Z | 1 |
| Sulman, GH | 1 |
| Acharya, SB | 1 |
| Goswami, NG | 1 |
| Debnath, PK | 1 |
| Krzysiek, J | 1 |
| Klimek, R | 1 |
| Golańska, Z | 1 |
| Harper, MJ | 2 |
| Skarnes, RC | 2 |
| Ward, CO | 1 |
| Gautieri, RF | 1 |
| Dora, A | 2 |
| Rahamimoff, E | 1 |
| Polishuk, WA | 1 |
| Rachamimoff, R | 1 |
| Sadovsky, A | 1 |
| Polishuk, Z | 1 |
| Sadowsky, E | 1 |
2 reviews available for cyproheptadine and Pregnancy
| Article | Year |
|---|---|
Pharmacologic therapy of patients with pituitary tumors secreting prolactin, growth hormone and adrenocorticotropin.
Topics: Adrenergic alpha-Antagonists; Adrenocorticotropic Hormone; Amenorrhea; Antineoplastic Agents; Bromoc | 1980 |
Drug management of adult vascular headaches (migraine and cluster headache): Part II--Prevention and attacks.
Topics: Adult; Amitriptyline; Belladonna Alkaloids; Cluster Headache; Cyproheptadine; Drug Combinations; Erg | 1984 |
1 trial available for cyproheptadine and Pregnancy
| Article | Year |
|---|---|
Cyproheptadine in anorexia nervosa.
Topics: Ambulatory Care; Anorexia Nervosa; Behavior Therapy; Body Weight; Clinical Trials as Topic; Cyprohep | 1979 |
41 other studies available for cyproheptadine and Pregnancy
| Article | Year |
|---|---|
The action of 5-hydroxytryptamine and some of its antagonists on the umbilical vessels of the human placenta.
Topics: Antihypertensive Agents; Cyproheptadine; Epinephrine; Histamine; Lysergic Acid Diethylamide; Phentol | 1957 |
The protective effect of an antihistaminic on the toxemia-like changes caused by aminoguanidine sulfate in pregnant rats.
Topics: Amine Oxidase (Copper-Containing); Animals; Cyproheptadine; Female; Guanidines; Pre-Eclampsia; Pregn | 1963 |
PREVENTION BY ANTAGONISTS OF THE TOXIC ACTION OF 5-HYDROXYTRYPTAMINE ON PREGNANCY.
Topics: Animals; Biomedical Research; Cyproheptadine; Female; Methysergide; Mice; Pregnancy; Pregnancy, Anim | 1963 |
THE 5-HYDROXYTRYPTAMINE CONTENT OF THE PLACENTA AND FOETUS DURING PREGNANCY IN MICE.
Topics: Animals; Blood Chemical Analysis; Blood Volume Determination; Cyproheptadine; Female; Fetus; Humans; | 1964 |
Effect of cyproheptadine on chlorpromazine stimulation of prolactin in women.
Topics: Chlorpromazine; Cyproheptadine; Female; Galactorrhea; Humans; Pregnancy; Prolactin; Prolactin Releas | 1981 |
The effect of cyproheptadine chlorhydrate on rat embryonic development.
Topics: Abnormalities, Multiple; Animals; Cyproheptadine; Embryo, Mammalian; Female; Fetus; Pregnancy; Rats; | 1983 |
Serotonergic control of oxytocin release during suckling in the rat: opposite effects in conscious and anesthetized rats.
Topics: Anesthesia; Animals; Animals, Suckling; Cyproheptadine; Female; Fenclonine; Fluoxetine; Lactation; O | 1983 |
Alterations in rat pancreatic B-cell function induced by prenatal exposure to cyproheptadine.
Topics: Animals; Blood Glucose; Cyproheptadine; Female; Glucose Tolerance Test; Insulin; Islets of Langerhan | 1984 |
Effect of maternal ethanol ingestion on control of growth hormone secretion by biogenic amines in rat offspring.
Topics: Alcohol Drinking; Animals; Cyproheptadine; Dopamine; Female; Growth Hormone; Insulin; Maternal-Fetal | 1984 |
Antagonism of the 5-HT-induced bronchoconstriction in the cat.
Topics: Animals; Bronchi; Carbachol; Cats; Clenbuterol; Cyproheptadine; Female; Hemodynamics; Ketanserin; Ma | 1983 |
[Plasma prolactin response to suckling stimulation in puerperal women].
Topics: Cyproheptadine; Dopamine; Female; Humans; Lactation; Metergoline; Postpartum Period; Pregnancy; Prol | 1984 |
The teratogenicity of cyproheptadine in two generations of Wistar rats.
Topics: Animals; Body Weight; Cyproheptadine; Female; Fetal Resorption; Gestational Age; Growth; Pregnancy; | 1982 |
Successful pregnancy after cyproheptadine treatment for Cushing's disease.
Topics: Adult; Cushing Syndrome; Cyproheptadine; Female; Humans; Pregnancy; Pregnancy Complications | 1982 |
Serotonin neuroleptics change patterns of preovulatory secretion of luteinizing hormone in rats.
Topics: Animals; Cyproheptadine; Female; Hypothalamus; Light; Luteinizing Hormone; Methysergide; Ovulation; | 1980 |
Pregnancy after cyproheptadine treatment for Cushing's disease.
Topics: Adult; Cushing Syndrome; Cyproheptadine; Female; Humans; Infant, Newborn; Male; Pregnancy; Remission | 1981 |
Two pregnancies in a woman with Cushing's syndrome treated with cyproheptadine. Case report.
Topics: Adult; Cushing Syndrome; Cyproheptadine; Female; Hormones; Humans; Pregnancy; Pregnancy Complication | 1980 |
[Effect of serotonin on the spontaneous uterine contraction during pregnancy].
Topics: Animals; Cyproheptadine; Dose-Response Relationship, Drug; Female; Mice; Mice, Inbred CBA; Pregnancy | 1998 |
The pulmonary neuroendocrine system and drainage of the fetal lung: effects of serotonin.
Topics: Amiloride; Animals; Cyproheptadine; Diuretics; Dose-Response Relationship, Drug; Embryo Loss; Embryo | 1999 |
Inhibition of stress-induced hyperprolactinaemia.
Topics: Adult; Cyproheptadine; Female; Galactorrhea; Humans; Pregnancy; Prolactin; Serotonin; Stress, Physio | 1977 |
Effect of three serotonin antagonists on plasma prolactin response to suckling in puerperal women.
Topics: Cyproheptadine; Ergolines; Female; Humans; Kinetics; Lactation; Metergoline; Methysergide; Postpartu | 1979 |
Cyproheptadine in the management of the galactorrhea-amenorrhea syndrome.
Topics: Adult; Amenorrhea; Cyproheptadine; Drug Evaluation; Female; Galactorrhea; Humans; Lactation Disorder | 1979 |
Cyproheptadine effects on pituitary function.
Topics: Amenorrhea; Cyproheptadine; Female; Galactorrhea; Humans; Pituitary Gland; Pregnancy; Prolactin; Ser | 1979 |
Antiserotonin treatment of hyperprolactinemic amenorrhea: long-term follow-up with metergoline, methysergide, and cyproheptadine.
Topics: Amenorrhea; Cyproheptadine; Female; Galactorrhea; Humans; Metergoline; Methysergide; Pituitary Neopl | 1978 |
Pretreatment predictors of outcome in anorexia nervosa.
Topics: Adolescent; Adult; Anorexia Nervosa; Behavior Therapy; Body Weight; Child; Cyproheptadine; Denial, P | 1979 |
Effect of indomethacin and cyproheptadine on onset of labour in rats.
Topics: Animals; Cyproheptadine; Drug Therapy, Combination; Female; Indomethacin; Labor, Obstetric; Pregnanc | 1977 |
Biogenic amine control of growth hormone secretion in the fetal and neonatal rat.
Topics: Animals; Animals, Newborn; Biogenic Amines; Cyproheptadine; Dimethoxyphenylethylamine; Dopamine; Fem | 1976 |
Teratogenicity of cyproheptadine in pregnant rats.
Topics: Abnormalities, Drug-Induced; Animals; Birth Weight; Cyproheptadine; Female; Fetal Resorption; Fetus; | 1975 |
Uterine and placental 5-HT profile in different gestational period of albino rats.
Topics: 5-Hydroxytryptophan; Animals; Cyproheptadine; Diethylstilbestrol; Estrus; Female; Placenta; Pregnanc | 1989 |
Susceptibility of fetal rat endocrine pancreas to the diabetogenic action of cyproheptadine.
Topics: Administration, Oral; Animals; Blood Glucose; Body Weight; Cyproheptadine; Female; Fetus; Glucagon; | 1986 |
[Pregnancy and labor in women after cyproheptadine treatment of psychogenic infertility].
Topics: Adult; Cyproheptadine; Female; Follow-Up Studies; Humans; Infertility, Female; Labor, Obstetric; Pre | 1985 |
Inhibition of abortion and fetal death produced by endotoxin or prostaglandin F2alpha.
Topics: Abortion, Induced; Abortion, Threatened; Animals; Cyproheptadine; Diarrhea; Endotoxins; Female; Feta | 1972 |
Effect of certain drugs on perfused human placenta. 8. Angiotensin-II antagonists.
Topics: Acetates; Angiotensin II; Atropine; Blood Pressure Determination; Cobalt; Cocaine; Cyproheptadine; D | 1968 |
Uptake of 3H-cyproheptadine by rat myometrium in vitro.
Topics: Animals; Benzocycloheptenes; Binding, Competitive; Calcium; Chlorpromazine; Cyproheptadine; Estradio | 1974 |
The use of antiserotonin-cyproheptadine HCL in pregnancy: an experimental and clinical study.
Topics: Abortion, Habitual; Abortion, Spontaneous; Animals; Cyproheptadine; Female; Fetus; Humans; Hydroxyin | 1972 |
Effect of the serotonin antagonist cyproheptadine on uterine and duodenal muscle contractions in rats.
Topics: Animals; Cyproheptadine; Depression, Chemical; Dose-Response Relationship, Drug; Duodenum; Estradiol | 1973 |
The role of prostaglandin in endotoxin-induced abortion and fetal death.
Topics: Abortion, Induced; Animals; Cyproheptadine; Depression, Chemical; Endotoxins; Female; Fetal Death; H | 1973 |
A trial of cyproheptadine in habitual abortion.
Topics: Abortion, Habitual; Cyproheptadine; Female; Humans; Pregnancy; Serotonin; Serotonin Antagonists | 1972 |
Cyproheptadine as an appetite stimulant.
Topics: Adult; Aged; Animals; Appetite; Body Weight; Cats; Child; Cyproheptadine; Dogs; Feeding and Eating D | 1970 |
[Prevention of hypothalamic habitual abortion by periactin].
Topics: Abortion, Habitual; Adult; Cyproheptadine; Female; Humans; Pregnancy; Serotonin | 1970 |
Effect of cyproheptadiae (periactin) on accumulation of (14C)5-hydroxytryptamine in pregnant rats.
Topics: Animals; Carbon Isotopes; Cyproheptadine; Drug Synergism; Female; Fetus; Injections, Subcutaneous; M | 1971 |
Prevention of serotonin abortion in pregnant rats by five serotonin antagonists.
Topics: Abortion, Habitual; Abortion, Spontaneous; Anilides; Animals; Cyproheptadine; Ergolines; Female; Fet | 1969 |