cyproheptadine has been researched along with Pleurisy in 7 studies
Cyproheptadine: A serotonin antagonist and a histamine H1 blocker used as antipruritic, appetite stimulant, antiallergic, and for the post-gastrectomy dumping syndrome, etc.
cyproheptadine : The product resulting from the formal oxidative coupling of position 5 of 5H-dibenzo[a,d]cycloheptene with position 4 of 1-methylpiperidine resulting in the formation of a double bond between the two fragments. It is a sedating antihistamine with antimuscarinic and calcium-channel blocking actions. It is used (particularly as the hydrochloride sesquihydrate) for the relief of allergic conditions including rhinitis, conjunctivitis due to inhalant allergens and foods, urticaria and angioedema, and in pruritic skin disorders. Unlike other antihistamines, it is also a seratonin receptor antagonist, making it useful in conditions such as vascular headache and anorexia.
Pleurisy: INFLAMMATION of PLEURA, the lining of the LUNG. When PARIETAL PLEURA is involved, there is pleuritic CHEST PAIN.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The relative contributions of inflammatory mediators to the increase in vascular permeability in antigen-induced pleurisy were examined in rats actively sensitized with ovalbumin." | 7.69 | Involvement of leukotrienes in allergic pleurisy in actively sensitized rats: inhibition by the lipoxygenase inhibitor T-0757 of the increase in vascular permeability and leukotriene E4 production. ( Kikuchi, M; Naito, K; Suzuki, T; Tsuzurahara, K; Yato, N, 1996) |
| "The econazole pleurisy development is monophasic and its peak value occurs between 8 and 12 hr after econazole injection." | 5.27 | Some characteristics of econazole-induced pleurisy in rats. ( Hanada, S; Hirano, MT; Oga, S, 1985) |
| "The relative contributions of inflammatory mediators to the increase in vascular permeability in antigen-induced pleurisy were examined in rats actively sensitized with ovalbumin." | 3.69 | Involvement of leukotrienes in allergic pleurisy in actively sensitized rats: inhibition by the lipoxygenase inhibitor T-0757 of the increase in vascular permeability and leukotriene E4 production. ( Kikuchi, M; Naito, K; Suzuki, T; Tsuzurahara, K; Yato, N, 1996) |
| "In the first 1 h after pleurisy induction, a significant decrease of total and differential cell count was observed in comparison with control values, despite the gradual enhancement of fluid leakage." | 1.29 | Pharmacological profile of rat pleurisy induced by Bothrops jararaca venom. ( Búrigo, AC; Calixto, JB; Medeiros, YS, 1996) |
| "Pretreatment with cyproheptadine (5 mg/kg), an inhibitor of both histamine and serotonin, significantly suppressed pleural fluid accumulation and the exudation rate at 0." | 1.28 | Involvement of platelet-activating factor in zymosan-induced rat pleurisy. ( Hayashi, M; Imai, Y; Oh-ishi, S, 1991) |
| "The econazole pleurisy development is monophasic and its peak value occurs between 8 and 12 hr after econazole injection." | 1.27 | Some characteristics of econazole-induced pleurisy in rats. ( Hanada, S; Hirano, MT; Oga, S, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (57.14) | 18.7374 |
| 1990's | 3 (42.86) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Búrigo, AC | 1 |
| Calixto, JB | 1 |
| Medeiros, YS | 1 |
| Kikuchi, M | 1 |
| Tsuzurahara, K | 1 |
| Suzuki, T | 1 |
| Yato, N | 1 |
| Naito, K | 1 |
| Dunn, CJ | 2 |
| Willoughby, DA | 2 |
| Imai, Y | 1 |
| Hayashi, M | 1 |
| Oh-ishi, S | 1 |
| Hanada, S | 1 |
| Oga, S | 1 |
| Hirano, MT | 1 |
| Vinegar, R | 1 |
| Truax, JF | 1 |
| Selph, JL | 1 |
7 other studies available for cyproheptadine and Pleurisy
| Article | Year |
|---|---|
Pharmacological profile of rat pleurisy induced by Bothrops jararaca venom.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Bothrops; Cell Count; Crotalid V | 1996 |
Involvement of leukotrienes in allergic pleurisy in actively sensitized rats: inhibition by the lipoxygenase inhibitor T-0757 of the increase in vascular permeability and leukotriene E4 production.
Topics: Amides; Animals; Capillary Permeability; Chromatography, High Pressure Liquid; Cyclooxygenase Inhibi | 1996 |
The response of the newborn rat to injury. I. Vascular and humoral aspects.
Topics: Age Factors; Albumins; Animals; Animals, Newborn; Bradykinin; Capillary Permeability; Carrageenan; C | 1975 |
The response of the newborn rat to intraleural dextran: vascular and cellular aspects.
Topics: Aging; Animals; Animals, Newborn; Cyproheptadine; Dextrans; Edema; Exudates and Transudates; Hindlim | 1975 |
Involvement of platelet-activating factor in zymosan-induced rat pleurisy.
Topics: Animals; Cyproheptadine; Eosinophils; Inflammation; Leukocytes; Male; Mast Cells; Neutrophils; Plate | 1991 |
Some characteristics of econazole-induced pleurisy in rats.
Topics: Animals; Carrageenan; Chlorpheniramine; Cyproheptadine; Dexamethasone; Econazole; Imidazoles; Inflam | 1985 |
Some quantitative temporal characteristics of carrageenin-induced pleurisy in the rat.
Topics: Animals; Aspirin; Carrageenan; Cyproheptadine; Edema; Exudates and Transudates; Injections; Leukocyt | 1973 |