cyproheptadine has been researched along with Myocardial Infarction in 2 studies
Cyproheptadine: A serotonin antagonist and a histamine H1 blocker used as antipruritic, appetite stimulant, antiallergic, and for the post-gastrectomy dumping syndrome, etc.
cyproheptadine : The product resulting from the formal oxidative coupling of position 5 of 5H-dibenzo[a,d]cycloheptene with position 4 of 1-methylpiperidine resulting in the formation of a double bond between the two fragments. It is a sedating antihistamine with antimuscarinic and calcium-channel blocking actions. It is used (particularly as the hydrochloride sesquihydrate) for the relief of allergic conditions including rhinitis, conjunctivitis due to inhalant allergens and foods, urticaria and angioedema, and in pruritic skin disorders. Unlike other antihistamines, it is also a seratonin receptor antagonist, making it useful in conditions such as vascular headache and anorexia.
Myocardial Infarction: NECROSIS of the MYOCARDIUM caused by an obstruction of the blood supply to the heart (CORONARY CIRCULATION).
| Excerpt | Relevance | Reference |
|---|---|---|
| "The antiarrhythmic effects of amitriptyline (1), its secondary amine metabolite nortriptyline (2), as well as cyclobenzaprine (3) and cyproheptadine (4), tertiary amine analogues of 1, were studied in conscious dogs 24 h after myocardial infarction." | 7.66 | Antiarrhythmic activity of amitriptyline analogues in conscious dogs after myocardial infarction: cyproheptadinium methiodide. ( Henderson, JD; Wilkerson, RD, 1980) |
| "Ischemic mitral regurgitation (MR) is primarily caused by left ventricle deformation, but leaflet thickening with fibrotic changes are also observed in the valve." | 5.72 | Effects of Cyproheptadine on Mitral Valve Remodeling and Regurgitation After Myocardial Infarction. ( Aikawa, E; Arsenault, M; Beaudoin, J; Clavel, MA; Couet, J; Deschênes, V; Hadjadj, S; Handschumacher, MD; Levine, RA; Marsit, O; Paquin, A; Pibarot, P; Sénéchal-Dumais, I, 2022) |
| "The antiarrhythmic effects of amitriptyline (1), its secondary amine metabolite nortriptyline (2), as well as cyclobenzaprine (3) and cyproheptadine (4), tertiary amine analogues of 1, were studied in conscious dogs 24 h after myocardial infarction." | 3.66 | Antiarrhythmic activity of amitriptyline analogues in conscious dogs after myocardial infarction: cyproheptadinium methiodide. ( Henderson, JD; Wilkerson, RD, 1980) |
| "Ischemic mitral regurgitation (MR) is primarily caused by left ventricle deformation, but leaflet thickening with fibrotic changes are also observed in the valve." | 1.72 | Effects of Cyproheptadine on Mitral Valve Remodeling and Regurgitation After Myocardial Infarction. ( Aikawa, E; Arsenault, M; Beaudoin, J; Clavel, MA; Couet, J; Deschênes, V; Hadjadj, S; Handschumacher, MD; Levine, RA; Marsit, O; Paquin, A; Pibarot, P; Sénéchal-Dumais, I, 2022) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wilkerson, RD | 1 |
| Henderson, JD | 1 |
| Marsit, O | 1 |
| Clavel, MA | 1 |
| Paquin, A | 1 |
| Deschênes, V | 1 |
| Hadjadj, S | 1 |
| Sénéchal-Dumais, I | 1 |
| Couet, J | 1 |
| Arsenault, M | 1 |
| Handschumacher, MD | 1 |
| Levine, RA | 1 |
| Aikawa, E | 1 |
| Pibarot, P | 1 |
| Beaudoin, J | 1 |
2 other studies available for cyproheptadine and Myocardial Infarction
| Article | Year |
|---|---|
Antiarrhythmic activity of amitriptyline analogues in conscious dogs after myocardial infarction: cyproheptadinium methiodide.
Topics: Amitriptyline; Animals; Anti-Arrhythmia Agents; Cyproheptadine; Dogs; Hemodynamics; Myocardial Infar | 1980 |
Effects of Cyproheptadine on Mitral Valve Remodeling and Regurgitation After Myocardial Infarction.
Topics: Animals; Aortic Valve; Aortic Valve Stenosis; Calcinosis; Cells, Cultured; Cyproheptadine; Fibrosis; | 2022 |