Page last updated: 2024-10-25

cyproheptadine and Muscle Relaxation

cyproheptadine has been researched along with Muscle Relaxation in 3 studies

Cyproheptadine: A serotonin antagonist and a histamine H1 blocker used as antipruritic, appetite stimulant, antiallergic, and for the post-gastrectomy dumping syndrome, etc.
cyproheptadine : The product resulting from the formal oxidative coupling of position 5 of 5H-dibenzo[a,d]cycloheptene with position 4 of 1-methylpiperidine resulting in the formation of a double bond between the two fragments. It is a sedating antihistamine with antimuscarinic and calcium-channel blocking actions. It is used (particularly as the hydrochloride sesquihydrate) for the relief of allergic conditions including rhinitis, conjunctivitis due to inhalant allergens and foods, urticaria and angioedema, and in pruritic skin disorders. Unlike other antihistamines, it is also a seratonin receptor antagonist, making it useful in conditions such as vascular headache and anorexia.

Muscle Relaxation: That phase of a muscle twitch during which a muscle returns to a resting position.

Research Excerpts

ExcerptRelevanceReference
"This single-dose placebo-controlled study examined whether a serotonin receptor (5-HT2) antagonist, cyproheptadine hydrochloride, could reduce delay in muscle relaxation of a key paretic long finger flexor muscle immediately after grip for persons with stroke."3.77Effect of a serotonin antagonist on delay in grip muscle relaxation for persons with chronic hemiparetic stroke. ( Bogey, RA; Fischer, HW; Kamper, DG; Rymer, WZ; Seo, NJ, 2011)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19901 (33.33)18.7374
1990's1 (33.33)18.2507
2000's0 (0.00)29.6817
2010's1 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Seo, NJ1
Fischer, HW1
Bogey, RA1
Rymer, WZ1
Kamper, DG1
Senaratne, M1
Kappagoda, T1
Murakami, H1
Kizawa, Y1
Sano, M1
Edamura, N1
Maruyama, C1
Yamazaki, A1

Other Studies

3 other studies available for cyproheptadine and Muscle Relaxation

ArticleYear
Effect of a serotonin antagonist on delay in grip muscle relaxation for persons with chronic hemiparetic stroke.
    Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology, 2011, Volume: 122, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Brain Stem; Cyproheptadine; Efferent Pathways; Electromyography; Fem

2011
Tetrodotoxin-resistant relaxation to transmural nerve stimulation in isolated saphenous vein.
    The American journal of physiology, 1984, Volume: 247, Issue:6 Pt 2

    Topics: Aminophylline; Animals; Biomechanical Phenomena; Cimetidine; Cyproheptadine; Dogs; Drug Resistance;

1984
Possible site of action of 2-methylserotonin in inducing relaxation of acetylcholine-induced contraction in the molluscan (Mytilus edulis) smooth muscle.
    Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology, 1992, Volume: 101, Issue:2

    Topics: Acetylcholine; Animals; Bivalvia; Cyclic AMP; Cyclic GMP; Cyproheptadine; Dose-Response Relationship

1992