cyproheptadine has been researched along with Multiple Myeloma in 3 studies
Cyproheptadine: A serotonin antagonist and a histamine H1 blocker used as antipruritic, appetite stimulant, antiallergic, and for the post-gastrectomy dumping syndrome, etc.
cyproheptadine : The product resulting from the formal oxidative coupling of position 5 of 5H-dibenzo[a,d]cycloheptene with position 4 of 1-methylpiperidine resulting in the formation of a double bond between the two fragments. It is a sedating antihistamine with antimuscarinic and calcium-channel blocking actions. It is used (particularly as the hydrochloride sesquihydrate) for the relief of allergic conditions including rhinitis, conjunctivitis due to inhalant allergens and foods, urticaria and angioedema, and in pruritic skin disorders. Unlike other antihistamines, it is also a seratonin receptor antagonist, making it useful in conditions such as vascular headache and anorexia.
Multiple Myeloma: A malignancy of mature PLASMA CELLS engaging in monoclonal immunoglobulin production. It is characterized by hyperglobulinemia, excess Bence-Jones proteins (free monoclonal IMMUNOGLOBULIN LIGHT CHAINS) in the urine, skeletal destruction, bone pain, and fractures. Other features include ANEMIA; HYPERCALCEMIA; and RENAL INSUFFICIENCY.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Li, J | 1 |
| Cao, B | 1 |
| Zhou, S | 1 |
| Zhu, J | 1 |
| Zhang, Z | 1 |
| Hou, T | 1 |
| Mao, X | 2 |
| Liang, SB | 1 |
| Hurren, R | 1 |
| Gronda, M | 1 |
| Chow, S | 1 |
| Xu, GW | 1 |
| Wang, X | 1 |
| Beheshti Zavareh, R | 1 |
| Jamal, N | 1 |
| Messner, H | 1 |
| Hedley, DW | 1 |
| Datti, A | 1 |
| Wrana, JL | 1 |
| Zhu, Y | 1 |
| Shi, CX | 1 |
| Lee, K | 1 |
| Tiedemann, R | 1 |
| Trudel, S | 1 |
| Stewart, AK | 1 |
| Schimmer, AD | 1 |
| Grey, HM | 1 |
| Kohler, PF | 1 |
1 review available for cyproheptadine and Multiple Myeloma
| Article | Year |
|---|---|
Cryoimmunoglobulins.
Topics: Amino Acids; Antibodies, Anti-Idiotypic; Antigen-Antibody Reactions; Blood Protein Disorders; Chemic | 1973 |
2 other studies available for cyproheptadine and Multiple Myeloma
| Article | Year |
|---|---|
Cyproheptadine-induced myeloma cell apoptosis is associated with inhibition of the PI3K/AKT signaling.
Topics: Adaptor Proteins, Signal Transducing; Apoptosis; Cell Cycle Proteins; Cell Line, Tumor; Cyproheptadi | 2013 |
Cyproheptadine displays preclinical activity in myeloma and leukemia.
Topics: Animals; Apoptosis; Cell Line; Cell Line, Tumor; Cyclin D1; Cyclin D2; Cyclin D3; Cyclins; Cyprohept | 2008 |