cyproheptadine has been researched along with Leanness in 8 studies
Cyproheptadine: A serotonin antagonist and a histamine H1 blocker used as antipruritic, appetite stimulant, antiallergic, and for the post-gastrectomy dumping syndrome, etc.
cyproheptadine : The product resulting from the formal oxidative coupling of position 5 of 5H-dibenzo[a,d]cycloheptene with position 4 of 1-methylpiperidine resulting in the formation of a double bond between the two fragments. It is a sedating antihistamine with antimuscarinic and calcium-channel blocking actions. It is used (particularly as the hydrochloride sesquihydrate) for the relief of allergic conditions including rhinitis, conjunctivitis due to inhalant allergens and foods, urticaria and angioedema, and in pruritic skin disorders. Unlike other antihistamines, it is also a seratonin receptor antagonist, making it useful in conditions such as vascular headache and anorexia.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Twenty-one underweight, otherwise healthy children were recruited." | 2.74 | Short-term cyproheptadine therapy in underweight children: effects on growth and serum insulin-like growth factor-I. ( Choubtum, L; Mahachoklertwattana, P; Poomthavorn, P; Sriphrapradang, A; Wanasuwankul, S, 2009) |
| "The cyproheptadine was initially prescribed to promote weight gain but its continued use seemed related to other psychological and/or pharmacological effects." | 1.27 | Cyproheptadine dependence associated with an atypical somatoform disorder. ( Craven, JL; Rodin, GM, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (75.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (12.50) | 29.6817 |
| 2010's | 1 (12.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Harrison, ME | 1 |
| Norris, ML | 1 |
| Robinson, A | 1 |
| Spettigue, W | 1 |
| Morrissey, M | 1 |
| Isserlin, L | 1 |
| Mahachoklertwattana, P | 1 |
| Wanasuwankul, S | 1 |
| Poomthavorn, P | 1 |
| Choubtum, L | 1 |
| Sriphrapradang, A | 1 |
| Silverstone, T | 1 |
| Schuyler, D | 1 |
| Craven, JL | 1 |
| Rodin, GM | 1 |
| Noble, RE | 1 |
| Andronic, A | 1 |
| Di Mascio, A | 1 |
| Martino, A | 1 |
| Musella, U | 1 |
| Ruffolo, A | 1 |
| Gerosa, HN | 1 |
| Bonet, JA | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effects of Cyproheptadine on Growth and Behavior in Pediatric Feeding Disorders[NCT02568007] | Phase 4 | 4 participants (Actual) | Interventional | 2015-12-31 | Terminated (stopped due to Unable to enroll adequate participants) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for cyproheptadine and Leanness
| Article | Year |
|---|---|
Use of cyproheptadine to stimulate appetite and body weight gain: A systematic review.
Topics: Anorexia Nervosa; Appetite; Appetite Stimulants; Cyproheptadine; Humans; Malnutrition; Randomized Co | 2019 |
4 trials available for cyproheptadine and Leanness
| Article | Year |
|---|---|
Short-term cyproheptadine therapy in underweight children: effects on growth and serum insulin-like growth factor-I.
Topics: Appetite Stimulants; Body Weight; Child; Child, Preschool; Cyproheptadine; Double-Blind Method; Ener | 2009 |
The effect of cyproheptadine on hunger, calorie intake and body weight in man.
Topics: Adult; Appetite; Body Weight; Clinical Trials as Topic; Cyproheptadine; Diet; Energy Metabolism; Fem | 1975 |
Effect of cyproheptadine on appetite and weight gain in adults.
Topics: Adolescent; Adult; Appetite; Body Weight; Clinical Trials as Topic; Cyproheptadine; Female; Humans; | 1969 |
Appetite-stimulating and weight-gain properties of cyproheptadine) (Periactin) in geriatric subjects.
Topics: Age Factors; Aged; Appetite; Clinical Trials as Topic; Cyproheptadine; Female; Humans; Male; Middle | 1971 |
3 other studies available for cyproheptadine and Leanness
| Article | Year |
|---|---|
Cyproheptadine dependence associated with an atypical somatoform disorder.
Topics: Adult; Body Image; Crohn Disease; Cyproheptadine; Female; Humans; Somatoform Disorders; Substance-Re | 1987 |
[On the clinical use of cyproheptadine as an anti-anorexic agent and its effects on the nutritional state].
Topics: Adolescent; Adult; Aged; Anorexia Nervosa; Appetite; Body Weight; Child; Child, Preschool; Cyprohept | 1971 |
[Thinness syndrome and cyproheptadine chlorhydrate].
Topics: Adolescent; Adult; Appetite; Body Weight; Child; Cyproheptadine; Female; Humans; Male; Serotonin; Th | 1968 |