Page last updated: 2024-10-25

cyproheptadine and Laron Syndrome

cyproheptadine has been researched along with Laron Syndrome in 1 studies

Cyproheptadine: A serotonin antagonist and a histamine H1 blocker used as antipruritic, appetite stimulant, antiallergic, and for the post-gastrectomy dumping syndrome, etc.
cyproheptadine : The product resulting from the formal oxidative coupling of position 5 of 5H-dibenzo[a,d]cycloheptene with position 4 of 1-methylpiperidine resulting in the formation of a double bond between the two fragments. It is a sedating antihistamine with antimuscarinic and calcium-channel blocking actions. It is used (particularly as the hydrochloride sesquihydrate) for the relief of allergic conditions including rhinitis, conjunctivitis due to inhalant allergens and foods, urticaria and angioedema, and in pruritic skin disorders. Unlike other antihistamines, it is also a seratonin receptor antagonist, making it useful in conditions such as vascular headache and anorexia.

Laron Syndrome: An autosomal recessive disorder characterized by short stature, defective GROWTH HORMONE RECEPTOR, and failure to generate INSULIN-LIKE GROWTH FACTOR I by GROWTH HORMONE. Laron syndrome is not a form of primary pituitary dwarfism (GROWTH HORMONE DEFICIENCY DWARFISM) but the result of mutation of the human GHR gene on chromosome 5.

Research Excerpts

ExcerptRelevanceReference
"Cyproheptadine HCl (CyproH) is an appetite-stimulating drug and while it was prescribed for a patient with growth hormone insensitivity syndrome (GHIS) for increasing appetite, his height growth was surprisingly increased."7.88A novel treatment for height growth in patients with growth hormone insensitivity syndrome by cyproheptadine hydrochloride. ( Nourbakhsh, M; Razzaghy-Azar, M, 2018)
"Cyproheptadine HCl (CyproH) is an appetite-stimulating drug and while it was prescribed for a patient with growth hormone insensitivity syndrome (GHIS) for increasing appetite, his height growth was surprisingly increased."3.88A novel treatment for height growth in patients with growth hormone insensitivity syndrome by cyproheptadine hydrochloride. ( Nourbakhsh, M; Razzaghy-Azar, M, 2018)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Razzaghy-Azar, M1
Nourbakhsh, M2

Other Studies

1 other study available for cyproheptadine and Laron Syndrome

ArticleYear
A novel treatment for height growth in patients with growth hormone insensitivity syndrome by cyproheptadine hydrochloride.
    Clinical endocrinology, 2018, Volume: 88, Issue:6

    Topics: Adolescent; Body Height; Child; Child, Preschool; Cyproheptadine; Female; Growth Hormone; Humans; In

2018