cyproheptadine has been researched along with Kidney Failure, Chronic in 2 studies
Cyproheptadine: A serotonin antagonist and a histamine H1 blocker used as antipruritic, appetite stimulant, antiallergic, and for the post-gastrectomy dumping syndrome, etc.
cyproheptadine : The product resulting from the formal oxidative coupling of position 5 of 5H-dibenzo[a,d]cycloheptene with position 4 of 1-methylpiperidine resulting in the formation of a double bond between the two fragments. It is a sedating antihistamine with antimuscarinic and calcium-channel blocking actions. It is used (particularly as the hydrochloride sesquihydrate) for the relief of allergic conditions including rhinitis, conjunctivitis due to inhalant allergens and foods, urticaria and angioedema, and in pruritic skin disorders. Unlike other antihistamines, it is also a seratonin receptor antagonist, making it useful in conditions such as vascular headache and anorexia.
Kidney Failure, Chronic: The end-stage of CHRONIC RENAL INSUFFICIENCY. It is characterized by the severe irreversible kidney damage (as measured by the level of PROTEINURIA) and the reduction in GLOMERULAR FILTRATION RATE to less than 15 ml per min (Kidney Foundation: Kidney Disease Outcome Quality Initiative, 2002). These patients generally require HEMODIALYSIS or KIDNEY TRANSPLANTATION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Loratadine was rapidly absorbed and the decline of plasma concentrations after attainment of the Cmax was biexponential in all subjects." | 1.28 | Pharmacokinetics of loratadine in patients with renal insufficiency. ( Halstenson, CE; Hilbert, J; Matzke, GR; Opsahl, JA; Perentesis, G; Radwanski, E; Zampaglione, N, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Matzke, GR | 1 |
| Halstenson, CE | 1 |
| Opsahl, JA | 1 |
| Hilbert, J | 1 |
| Perentesis, G | 1 |
| Radwanski, E | 1 |
| Zampaglione, N | 1 |
| Barba, A | 1 |
| Mangas-Rojas, A | 1 |
| García, JF | 1 |
| Zamora-Madaria, E | 1 |
2 other studies available for cyproheptadine and Kidney Failure, Chronic
| Article | Year |
|---|---|
Pharmacokinetics of loratadine in patients with renal insufficiency.
Topics: Adult; Cyproheptadine; Female; Humans; Kidney Failure, Chronic; Loratadine; Male; Middle Aged; Piper | 1990 |
[Effect of changes in hypothalamic neurotransmitters on the release of growth hormone by thyrotropin-releasing hormone in chronic renal insufficiency on hemodialysis].
Topics: Adult; Cyproheptadine; Female; Growth Hormone; Humans; Hypothalamo-Hypophyseal System; Kidney Failur | 1988 |