Page last updated: 2024-10-25

cyproheptadine and Ischemia

cyproheptadine has been researched along with Ischemia in 4 studies

Cyproheptadine: A serotonin antagonist and a histamine H1 blocker used as antipruritic, appetite stimulant, antiallergic, and for the post-gastrectomy dumping syndrome, etc.
cyproheptadine : The product resulting from the formal oxidative coupling of position 5 of 5H-dibenzo[a,d]cycloheptene with position 4 of 1-methylpiperidine resulting in the formation of a double bond between the two fragments. It is a sedating antihistamine with antimuscarinic and calcium-channel blocking actions. It is used (particularly as the hydrochloride sesquihydrate) for the relief of allergic conditions including rhinitis, conjunctivitis due to inhalant allergens and foods, urticaria and angioedema, and in pruritic skin disorders. Unlike other antihistamines, it is also a seratonin receptor antagonist, making it useful in conditions such as vascular headache and anorexia.

Ischemia: A hypoperfusion of the BLOOD through an organ or tissue caused by a PATHOLOGIC CONSTRICTION or obstruction of its BLOOD VESSELS, or an absence of BLOOD CIRCULATION.

Research Excerpts

ExcerptRelevanceReference
" Administration of cyproheptadine (which is available for clinical use) 15 minutes before or 5 minutes after the onset increased the duration of experimental rabbit spinal cord ischemia required to produce irreversible paraplegia."3.67Cyproheptadine reduces or prevents ischemic central nervous system damage. ( Zivin, JA, 1985)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19903 (75.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's1 (25.00)2.80

Authors

AuthorsStudies
Sharma, N1
Sankrityayan, H1
Kale, A1
Gaikwad, AB1
Selye, H2
Pahk, US1
Somogyi, A2
Zivin, JA1

Other Studies

4 other studies available for cyproheptadine and Ischemia

ArticleYear
Role of SET7/9 in the progression of ischemic renal injury in diabetic and non-diabetic rats.
    Biochemical and biophysical research communications, 2020, 07-12, Volume: 528, Issue:1

    Topics: Animals; Biomarkers; Cyproheptadine; Diabetes Mellitus, Experimental; Disease Progression; Histone-L

2020
Prevention of renal necrosis by stress.
    JAMA, 1967, Sep-25, Volume: 201, Issue:13

    Topics: Animals; Chlorpromazine; Cyproheptadine; Ischemia; Kidney Diseases; Necrosis; Rats; Stress, Physiolo

1967
Cyproheptadine reduces or prevents ischemic central nervous system damage.
    Neurology, 1985, Volume: 35, Issue:4

    Topics: Animals; Cyproheptadine; Ischemia; Male; Rabbits; Serotonin Antagonists; Spinal Cord

1985
Tourniquet poditis--an experimental pedal inflammation in the rat.
    Arzneimittel-Forschung, 1969, Volume: 19, Issue:6

    Topics: Animals; Anti-Bacterial Agents; Chlorpromazine; Cyproheptadine; Depression, Chemical; Dextrans; Dibe

1969