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cyproheptadine and Hypoxia

cyproheptadine has been researched along with Hypoxia in 4 studies

Cyproheptadine: A serotonin antagonist and a histamine H1 blocker used as antipruritic, appetite stimulant, antiallergic, and for the post-gastrectomy dumping syndrome, etc.
cyproheptadine : The product resulting from the formal oxidative coupling of position 5 of 5H-dibenzo[a,d]cycloheptene with position 4 of 1-methylpiperidine resulting in the formation of a double bond between the two fragments. It is a sedating antihistamine with antimuscarinic and calcium-channel blocking actions. It is used (particularly as the hydrochloride sesquihydrate) for the relief of allergic conditions including rhinitis, conjunctivitis due to inhalant allergens and foods, urticaria and angioedema, and in pruritic skin disorders. Unlike other antihistamines, it is also a seratonin receptor antagonist, making it useful in conditions such as vascular headache and anorexia.

Hypoxia: Sub-optimal OXYGEN levels in the ambient air of living organisms.

Research Excerpts

ExcerptRelevanceReference
"The 5-HT antagonists ketanserin, mianserin, methysergide, and cyproheptadine and the 5-HT uptake inhibitors fluoxetine and zimeldine were evaluated for their ability to protect against an hypoxia-induced performance deficit in a passive avoidance (PA) task."3.67Manipulation of serotonin protects against an hypoxia-induced deficit of a passive avoidance response in rats. ( DeNoble, VJ; Spencer, KR; Strek, KF, 1989)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19903 (75.00)18.7374
1990's1 (25.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
CATER, DB1
SCHOENIGER, EL1
WATKINSON, DA1
Barer, GR1
Emery, CJ1
Mohammed, FH1
Mungall, IP1
Gonzales, GF1
Rodriguez, L1
Valera, J1
Sandoval, E1
Garcia-Hjarles, M1
Strek, KF1
Spencer, KR1
DeNoble, VJ1

Other Studies

4 other studies available for cyproheptadine and Hypoxia

ArticleYear
EFFECT OF BREATHING HIGH PRESSURE OXYGEN UPON TISSUE OXYGEN TENSION IN RAT AND MOUSE TUMOURS.
    Acta radiologica: therapy, physics, biology, 1963, Volume: 1

    Topics: Animals; Carcinoma, Hepatocellular; Cyproheptadine; Hypoxia; Liver Neoplasms; Mammary Neoplasms, Ani

1963
H1 and H2 histamine actions on lung vessels; their relevance to hypoxic vasoconstriction.
    Quarterly journal of experimental physiology and cognate medical sciences, 1978, Volume: 63, Issue:2

    Topics: Animals; Blood Vessels; Cats; Cyproheptadine; Dose-Response Relationship, Drug; Ferrets; Histamine;

1978
Prevention of high altitude-induced testicular disturbances by previous treatment with cyproheptadine in male rats.
    Archives of andrology, 1990, Volume: 24, Issue:2

    Topics: Altitude Sickness; Animals; Cyproheptadine; Epididymis; Hypoxia; Male; Organ Size; Rats; Serotonin;

1990
Manipulation of serotonin protects against an hypoxia-induced deficit of a passive avoidance response in rats.
    Pharmacology, biochemistry, and behavior, 1989, Volume: 33, Issue:1

    Topics: Animals; Avoidance Learning; Cyproheptadine; Dose-Response Relationship, Drug; Fluoxetine; Hypoxia;

1989