cyproheptadine has been researched along with Hypopituitarism in 2 studies
Cyproheptadine: A serotonin antagonist and a histamine H1 blocker used as antipruritic, appetite stimulant, antiallergic, and for the post-gastrectomy dumping syndrome, etc.
cyproheptadine : The product resulting from the formal oxidative coupling of position 5 of 5H-dibenzo[a,d]cycloheptene with position 4 of 1-methylpiperidine resulting in the formation of a double bond between the two fragments. It is a sedating antihistamine with antimuscarinic and calcium-channel blocking actions. It is used (particularly as the hydrochloride sesquihydrate) for the relief of allergic conditions including rhinitis, conjunctivitis due to inhalant allergens and foods, urticaria and angioedema, and in pruritic skin disorders. Unlike other antihistamines, it is also a seratonin receptor antagonist, making it useful in conditions such as vascular headache and anorexia.
Hypopituitarism: Diminution or cessation of secretion of one or more hormones from the anterior pituitary gland (including LH; FOLLICLE STIMULATING HORMONE; SOMATOTROPIN; and CORTICOTROPIN). This may result from surgical or radiation ablation, non-secretory PITUITARY NEOPLASMS, metastatic tumors, infarction, PITUITARY APOPLEXY, infiltrative or granulomatous processes, and other conditions.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The cortisol response to insulin hypoglycemia was determined in ten hypopituitary children treated for four months with both growth hormone and cyproheptadine, and in six other children with hypopituitarism treated for four months with hGH alone." | 7.66 | The effect of cyproheptadine and human growth hormone on adrenocortical function in children with hypopituitarism. ( Becker, DJ; Drash, AL; Foley, TP; Gutai, JP; Kenien, AG; Pang, SJ; Postellon, DC; Zeidner, DL, 1978) |
| "The cortisol response to insulin hypoglycemia was determined in ten hypopituitary children treated for four months with both growth hormone and cyproheptadine, and in six other children with hypopituitarism treated for four months with hGH alone." | 3.66 | The effect of cyproheptadine and human growth hormone on adrenocortical function in children with hypopituitarism. ( Becker, DJ; Drash, AL; Foley, TP; Gutai, JP; Kenien, AG; Pang, SJ; Postellon, DC; Zeidner, DL, 1978) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kenien, AG | 1 |
| Zeidner, DL | 1 |
| Pang, SJ | 1 |
| Becker, DJ | 1 |
| Postellon, DC | 1 |
| Gutai, JP | 1 |
| Foley, TP | 1 |
| Drash, AL | 1 |
| Kaplowitz, PB | 1 |
| Jennings, S | 1 |
1 trial available for cyproheptadine and Hypopituitarism
| Article | Year |
|---|---|
Enhancement of linear growth and weight gain by cyproheptadine in children with hypopituitarism receiving growth hormone therapy.
Topics: Body Height; Body Weight; Child; Child, Preschool; Cyproheptadine; Drug Therapy, Combination; Growth | 1987 |
1 other study available for cyproheptadine and Hypopituitarism
| Article | Year |
|---|---|
The effect of cyproheptadine and human growth hormone on adrenocortical function in children with hypopituitarism.
Topics: Adrenal Cortex; Child, Preschool; Cyproheptadine; Growth; Growth Hormone; Humans; Hypopituitarism; M | 1978 |