cyproheptadine has been researched along with Hypersensitivity in 37 studies
Cyproheptadine: A serotonin antagonist and a histamine H1 blocker used as antipruritic, appetite stimulant, antiallergic, and for the post-gastrectomy dumping syndrome, etc.
cyproheptadine : The product resulting from the formal oxidative coupling of position 5 of 5H-dibenzo[a,d]cycloheptene with position 4 of 1-methylpiperidine resulting in the formation of a double bond between the two fragments. It is a sedating antihistamine with antimuscarinic and calcium-channel blocking actions. It is used (particularly as the hydrochloride sesquihydrate) for the relief of allergic conditions including rhinitis, conjunctivitis due to inhalant allergens and foods, urticaria and angioedema, and in pruritic skin disorders. Unlike other antihistamines, it is also a seratonin receptor antagonist, making it useful in conditions such as vascular headache and anorexia.
Hypersensitivity: Altered reactivity to an antigen, which can result in pathologic reactions upon subsequent exposure to that particular antigen.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Cyproheptadine hydrochloride was administered to 20 presumed or proven allergic cats to determine its efficacy in controlling pruritus." | 3.70 | Observations on the use of cyproheptadine hydrochloride as an antipruritic agent in allergic cats. ( Beningo, KE; Miller, WH; Rothstein, E; Scott, DW, 1998) |
| " The present studies compared loratadine and terfenadine, another non-sedating antihistamine, for their ability to inhibit the bronchial response to histamine and other autacoids which have been implicated as contributing to the symptoms of an allergic reaction." | 3.67 | Antiallergic activity of loratadine, a non-sedating antihistamine. ( Chapman, RW; Gulbenkian, A; Kreutner, W; Siegel, MI, 1987) |
| "Terfenadine was more effective than both loratadine (P less than ." | 2.67 | Suppression of epicutaneous reactivity by terfenadine and loratadine. ( Small, P, 1992) |
| "Cyproheptadine hydrochloride was administered orally at 0." | 2.67 | Failure of cyproheptadine hydrochloride as an antipruritic agent in allergic dogs: results of a double-blinded, placebo-controlled study. ( Cayatte, SM; Decker, GA; Miller, WH; Scott, DW, 1992) |
| "Rupatadine has dual affinity for histamine H1 -receptors and PAF receptors." | 2.52 | Update on rupatadine in the management of allergic disorders. ( Bachert, C; Bousquet, J; Canonica, GW; Giménez-Arnau, A; Kowalski, ML; Maurer, M; Mullol, J; Ryan, D; Scadding, G; Simons, FE, 2015) |
| "Loratadine is an addition to the class of nonsedating antihistamines which includes terfenadine, astemizole, and acrivastine." | 2.38 | Loratadine: a nonsedating antihistamine with once-daily dosing. ( Barenholtz, HA; McLeod, DC, 1989) |
| "The patient had no history of allergy or hornet stings." | 1.32 | Hornet sting induced systemic allergic reaction and large local reaction with bulle formation and rhabdomyolysis. ( Chang, MY; Lin, CC; Lin, JL, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 25 (67.57) | 18.7374 |
| 1990's | 6 (16.22) | 18.2507 |
| 2000's | 5 (13.51) | 29.6817 |
| 2010's | 1 (2.70) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Devlin, JP | 1 |
| Bauen, A | 1 |
| Possanza, GJ | 1 |
| Stewart, PB | 1 |
| Mullol, J | 1 |
| Bousquet, J | 1 |
| Bachert, C | 1 |
| Canonica, GW | 1 |
| Giménez-Arnau, A | 1 |
| Kowalski, ML | 1 |
| Simons, FE | 1 |
| Maurer, M | 1 |
| Ryan, D | 1 |
| Scadding, G | 1 |
| SHERROD, TR | 1 |
| LOEW, ER | 1 |
| SCHLOEMER, HF | 1 |
| FLANDIN, C | 1 |
| MILLOT, J | 1 |
| DANIELOPOLU, D | 1 |
| POPESCO, M | 1 |
| MEZINCESCO, E | 1 |
| Auclair, D | 1 |
| Hopwood, JJ | 1 |
| Brooks, DA | 1 |
| Lemontt, JF | 1 |
| Crawley, AC | 1 |
| RUIZ MORENO, G | 1 |
| TRACCHIA, R | 1 |
| BAZA, A | 1 |
| GIRARD, JP | 1 |
| BRUUN, E | 1 |
| GRATER, WC | 1 |
| SAPORITI, EM | 1 |
| MARINO, A | 1 |
| MATSUMURA, T | 1 |
| KUROUME, Y | 1 |
| TATENO, K | 1 |
| KOBORI, T | 1 |
| ISHIHARA, K | 1 |
| HASEGAWA, K | 1 |
| KIMURA, Y | 1 |
| ARAI, Y | 1 |
| OKUNI, H | 1 |
| MATHOV, E | 2 |
| ALBORES, JM | 1 |
| KALIMAN, M | 1 |
| VARAN, J | 1 |
| Lin, CC | 1 |
| Chang, MY | 1 |
| Lin, JL | 1 |
| Rahman, MA | 1 |
| Inoue, T | 1 |
| Kamei, C | 1 |
| Camelo-Nunes, IC | 1 |
| Keam, SJ | 1 |
| Plosker, GL | 1 |
| Scott, DW | 2 |
| Rothstein, E | 1 |
| Beningo, KE | 1 |
| Miller, WH | 2 |
| Sokolova, TS | 1 |
| Stepanova, II | 1 |
| Zakhidov, IuV | 1 |
| Mamedova, TG | 1 |
| Horváth, E | 2 |
| Small, P | 1 |
| Marzio, L | 1 |
| Blennerhassett, P | 1 |
| Vermillion, D | 1 |
| Chiverton, S | 1 |
| Collins, S | 1 |
| Decker, GA | 1 |
| Cayatte, SM | 1 |
| Ryhal, BT | 1 |
| Fletcher, MP | 1 |
| Lei, HY | 1 |
| Wang, JY | 1 |
| Chang, TT | 1 |
| Wang, CC | 1 |
| Daniels, C | 1 |
| Temple, DM | 1 |
| Kreutner, W | 1 |
| Chapman, RW | 1 |
| Gulbenkian, A | 1 |
| Siegel, MI | 1 |
| Barenholtz, HA | 1 |
| McLeod, DC | 1 |
| Proud, D | 1 |
| Kagey-Sobotka, A | 1 |
| Naclerio, RM | 1 |
| Lichtenstein, LM | 1 |
| Schwark, WS | 1 |
| Tozzi, S | 1 |
| Roth, FE | 1 |
| Tabachnick, II | 1 |
| Golub, ES | 1 |
| Spitznagel, JK | 1 |
| Pérez Martín, J | 1 |
5 reviews available for cyproheptadine and Hypersensitivity
| Article | Year |
|---|---|
Update on rupatadine in the management of allergic disorders.
Topics: Cyproheptadine; Humans; Hypersensitivity; Platelet Activating Factor; Treatment Outcome | 2015 |
New antihistamines: a critical view.
Topics: Anti-Allergic Agents; Blood-Brain Barrier; Central Nervous System Diseases; Cetirizine; Child; Cypro | 2006 |
Rupatadine: a review of its use in the management of allergic disorders.
Topics: Adolescent; Adult; Aged; Animals; Anti-Allergic Agents; Cyproheptadine; Drug Interactions; Humans; H | 2007 |
The second-generation antihistamines. What makes them different?
Topics: Astemizole; Benzhydryl Compounds; Benzimidazoles; Blood-Brain Barrier; Brain; Cetirizine; Cyprohepta | 1991 |
Loratadine: a nonsedating antihistamine with once-daily dosing.
Topics: Cyproheptadine; Humans; Hypersensitivity; Loratadine | 1989 |
2 trials available for cyproheptadine and Hypersensitivity
| Article | Year |
|---|---|
Suppression of epicutaneous reactivity by terfenadine and loratadine.
Topics: Cyproheptadine; Double-Blind Method; Female; Histamine H1 Antagonists; Humans; Hypersensitivity; Lor | 1992 |
Failure of cyproheptadine hydrochloride as an antipruritic agent in allergic dogs: results of a double-blinded, placebo-controlled study.
Topics: Animals; Cyproheptadine; Dog Diseases; Dogs; Double-Blind Method; Female; Hyperphagia; Hypersensitiv | 1992 |
30 other studies available for cyproheptadine and Hypersensitivity
| Article | Year |
|---|---|
Antiallergic 9-oxo-11-hydroxy-5H,9H-[2]benzopyrano[4,3-g][1]benzopyrans.
Topics: Anaphylaxis; Animals; Benzopyrans; Guinea Pigs; Hypersensitivity; In Vitro Techniques; Muscle Contra | 1978 |
Pharmacological properties of antihistamine drugs, benadryl, pyribenzamine and neoantergan.
Topics: Amino Acids; Anaphylaxis; Aniline Compounds; Cyproheptadine; Diphenhydramine; Drug Combinations; Eth | 1947 |
A case of intolerance to the antergan; antagonistic action of histamine.
Topics: Cyproheptadine; Hypersensitivity; Immune System Diseases | 1945 |
Parasympathyrenic and histaminofrenic action of the antigan (2339-RP); comparative action of atropine and atropine-antergan.
Topics: Anaphylaxis; Aniline Compounds; Atropine; Cyproheptadine; Hypersensitivity; Immune System Diseases | 1945 |
Replacement therapy in Mucopolysaccharidosis type VI: advantages of early onset of therapy.
Topics: Age Factors; Animals; Animals, Newborn; Autopsy; Bone and Bones; Cats; Complement Hemolytic Activity | 2003 |
[Cyproheptadine in allergic reactions].
Topics: Anti-Allergic Agents; Cyproheptadine; Histamine H1 Antagonists; Hypersensitivity; Serotonin; Seroton | 1961 |
[Antiallergic properties of the cyproheptadine-dexamethasone combination. Antiserotonin activity of cyprohepatadine].
Topics: Anti-Allergic Agents; Cyproheptadine; Dexamethasone; Histamine H1 Antagonists; Hypersensitivity; Imm | 1962 |
LETMAN H: Clinical results of treatment with anti-serotonin in allergic patients.
Topics: Anti-Allergic Agents; Cyproheptadine; Histamine H1 Antagonists; Hypersensitivity; Imipramine; Seroto | 1962 |
SEROTONIN AND ANTISEROTONINS IN ALLERGY.
Topics: Child; Cyproheptadine; Ergot Alkaloids; Hypersensitivity; Methysergide; Selective Serotonin Reuptake | 1963 |
[THE ANTIALLERGIC DRUGS AND THEIR MODE OF ACTION].
Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Anti-Allergic Agents; Ascorbic Acid; Bradykini | 1963 |
[ON THE THERAPEUTIC EFFECT OF SEROTONIN INHIBITORS ON ALLERGIC DISEASES IN CHILDREN].
Topics: Adolescent; Asthma; Bronchitis; Child; Common Cold; Cyproheptadine; Dermatology; Eczema; Exanthema; | 1964 |
[SKIN DISEASES ASSOCIATED WITH SEROTONIN AND PERIACTIN].
Topics: Blood Chemical Analysis; Cyproheptadine; Hydroxyindoleacetic Acid; Hypersensitivity; Indoleacetic Ac | 1964 |
[EFFECT OF ANTI-ALLERGIC AGENTS ON THE METABOLISM PROCESS FROM TRYPTOPHAN TO SEROTONIN].
Topics: 5-Hydroxytryptophan; Anti-Allergic Agents; Cyproheptadine; Hypersensitivity; Indoles; Lysergic Acid | 1964 |
[Action of an anti-serotonin-antihistamine drug (cyproheptadine) on infantile allergy, evaluated by the method of the triple blind test].
Topics: Anti-Allergic Agents; Child; Cyproheptadine; Histamine H1 Antagonists; Humans; Hypersensitivity; Inf | 1961 |
[Poteniation of dexamethasone and cyproheptadine. Their use in allergic patients with anorexia and malnutrition].
Topics: Anorexia; Anorexia Nervosa; Anti-Allergic Agents; Cyproheptadine; Dexamethasone; Histamine H1 Antago | 1962 |
Hornet sting induced systemic allergic reaction and large local reaction with bulle formation and rhabdomyolysis.
Topics: Adrenal Cortex Hormones; Adult; Animals; Anti-Allergic Agents; Blister; Cyproheptadine; Histamine H1 | 2003 |
Role of substance P in allergic nasal symptoms in rats.
Topics: Animals; Antigens; Cyproheptadine; Dibenzazepines; Dibenzoxepins; Dose-Response Relationship, Drug; | 2006 |
Observations on the use of cyproheptadine hydrochloride as an antipruritic agent in allergic cats.
Topics: Administration, Oral; Animals; Antipruritics; Cat Diseases; Cats; Cyproheptadine; Female; Hypersensi | 1998 |
[Use of peritol in allergic diseases in children].
Topics: Child; Child, Preschool; Cyproheptadine; Drug Evaluation; Humans; Hypersensitivity; Infant; Time Fac | 1979 |
[Treatment of allergic diseases with cyproheptadine].
Topics: Adolescent; Adult; Cyproheptadine; Humans; Hypersensitivity; Male; Middle Aged; Skin Diseases | 1976 |
Distribution of mast cells in intestinal muscle of nematode-sensitized rats.
Topics: Animals; Antigens, Helminth; Cell Count; Colon; Cyproheptadine; Female; Hypersensitivity; In Vitro T | 1992 |
Hepatitis B surface antigen induces an early-type hypersensitivity.
Topics: Animals; Capillary Permeability; Cyproheptadine; Hepatitis B Surface Antigens; Hypersensitivity; Imm | 1991 |
The inhibition by azatadine of the immunological release of leukotrienes and histamine from human lung fragments.
Topics: Cyproheptadine; Histamine H1 Antagonists; Histamine Release; Humans; Hypersensitivity; In Vitro Tech | 1986 |
Antiallergic activity of loratadine, a non-sedating antihistamine.
Topics: Animals; Benzhydryl Compounds; Bronchial Spasm; Calcium; Cyproheptadine; Guinea Pigs; Histamine Anta | 1987 |
Pharmacology of upper airways challenge.
Topics: Aspirin; Cyproheptadine; Exocytosis; Humans; Hypersensitivity; Inflammation; Mast Cells; Nasal Mucos | 1987 |
Pharmacologic management of allergic diseases.
Topics: Administration, Oral; Administration, Topical; Anaphylaxis; Animals; Anti-Inflammatory Agents; Cromo | 1974 |
The pharmacology of azatadine, a potential antiallergy drug.
Topics: Anaphylaxis; Animals; Cyproheptadine; Dose-Response Relationship, Drug; Female; Guinea Pigs; Histami | 1974 |
The role of lysosomes in hypersensitivity reactions: tissue damage by polymorphonuclear neutrophil lysosomes.
Topics: Animals; Arthus Reaction; Capillary Permeability; Cortisone; Cyproheptadine; Cytoplasmic Granules; E | 1965 |
Peritol (cyproheptadine) in allergic skin diseases.
Topics: Adolescent; Adult; Cyproheptadine; Humans; Hypersensitivity; Male; Middle Aged; Skin Diseases | 1973 |
[Evaluation of dexamethasone-cyproheptadine in children with allergic syndromes and reactive dermatitis].
Topics: Adolescent; Child; Child, Preschool; Cyproheptadine; Dermatitis; Dexamethasone; Evaluation Studies a | 1972 |