cyproheptadine has been researched along with Hyperphagia in 8 studies
Cyproheptadine: A serotonin antagonist and a histamine H1 blocker used as antipruritic, appetite stimulant, antiallergic, and for the post-gastrectomy dumping syndrome, etc.
cyproheptadine : The product resulting from the formal oxidative coupling of position 5 of 5H-dibenzo[a,d]cycloheptene with position 4 of 1-methylpiperidine resulting in the formation of a double bond between the two fragments. It is a sedating antihistamine with antimuscarinic and calcium-channel blocking actions. It is used (particularly as the hydrochloride sesquihydrate) for the relief of allergic conditions including rhinitis, conjunctivitis due to inhalant allergens and foods, urticaria and angioedema, and in pruritic skin disorders. Unlike other antihistamines, it is also a seratonin receptor antagonist, making it useful in conditions such as vascular headache and anorexia.
Hyperphagia: Ingestion of a greater than optimal quantity of food.
| Excerpt | Relevance | Reference |
|---|---|---|
| " To examine the possible contribution of serotonin (5-HT) and histamine (H) receptor blockade in antipsychotic-associated hyperphagia, rats were trained to drink a palatable, high-calorie fat emulsion (10% intralipid) during 30-min sessions and were tested following pretreatment with mepyramine (H1 receptor antagonist), metergoline (5-HT(1/2) receptor antagonist), cyproheptadine (H1 and 5-HT(2A/2B/2C) and muscarinic receptor antagonist), SB 242084 (5-HT2C receptor antagonist) and an SB 242084-mepyramine combination." | 3.72 | Serotonergic and histaminergic mechanisms involved in intralipid drinking? ( Clifton, PG; Hartfield, AW; Moore, NA, 2003) |
| "Cyproheptadine hydrochloride was administered orally at 0." | 2.67 | Failure of cyproheptadine hydrochloride as an antipruritic agent in allergic dogs: results of a double-blinded, placebo-controlled study. ( Cayatte, SM; Decker, GA; Miller, WH; Scott, DW, 1992) |
| "Increased research focusing on the eating disorders has put the clinician on firmer ground when choosing appropriate psychopharmacologic treatments." | 2.37 | Pharmacologic treatment of eating disorders. ( Gwirtsman, H; Jimerson, DC; Kaye, W; Weintraub, M, 1984) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (75.00) | 18.7374 |
| 1990's | 1 (12.50) | 18.2507 |
| 2000's | 1 (12.50) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hartfield, AW | 1 |
| Moore, NA | 1 |
| Clifton, PG | 1 |
| Gwirtsman, H | 1 |
| Kaye, W | 1 |
| Weintraub, M | 1 |
| Jimerson, DC | 1 |
| Johnson, C | 1 |
| Stuckey, M | 1 |
| Mitchell, J | 1 |
| Halmi, KA | 2 |
| Herzog, DB | 1 |
| Scott, DW | 1 |
| Miller, WH | 1 |
| Decker, GA | 1 |
| Cayatte, SM | 1 |
| Eckert, E | 1 |
| LaDu, TJ | 1 |
| Cohen, J | 1 |
| Autry, JH | 1 |
| Stover, ES | 1 |
| Reatig, N | 1 |
| Casper, R | 1 |
4 reviews available for cyproheptadine and Hyperphagia
| Article | Year |
|---|---|
Pharmacologic treatment of eating disorders.
Topics: Anorexia Nervosa; Anticonvulsants; Antidepressive Agents; Antidepressive Agents, Tricyclic; Central | 1984 |
Psychopharmacological treatment of anorexia nervosa and bulimia. Review and synthesis.
Topics: Adrenocorticotropic Hormone; Anorexia Nervosa; Antidepressive Agents, Tricyclic; Chlorpromazine; Cyp | 1983 |
The state of research in anorexia nervosa and bulimia.
Topics: Adolescent; Adult; Age Factors; Amenorrhea; Anorexia Nervosa; Behavior Therapy; Body Image; Body Wei | 1983 |
Pharmacotherapy of anorexia nervosa and bulimia.
Topics: Amitriptyline; Anorexia Nervosa; Antidepressive Agents, Tricyclic; Chlorpromazine; Clinical Trials a | 1984 |
4 trials available for cyproheptadine and Hyperphagia
| Article | Year |
|---|---|
Pharmacotherapy of anorexia nervosa and bulimia.
Topics: Amitriptyline; Anorexia Nervosa; Antidepressive Agents, Tricyclic; Chlorpromazine; Clinical Trials a | 1984 |
Failure of cyproheptadine hydrochloride as an antipruritic agent in allergic dogs: results of a double-blinded, placebo-controlled study.
Topics: Animals; Cyproheptadine; Dog Diseases; Dogs; Double-Blind Method; Female; Hyperphagia; Hypersensitiv | 1992 |
Anorexia nervosa. Treatment efficacy of cyproheptadine and amitriptyline.
Topics: Adolescent; Adult; Amitriptyline; Anorexia Nervosa; Body Weight; Clinical Trials as Topic; Cyprohept | 1986 |
Anorexia nervosa and bulimia.
Topics: Adolescent; Anorexia Nervosa; Antidepressive Agents, Tricyclic; Behavior Therapy; Clinical Trials as | 1986 |
1 other study available for cyproheptadine and Hyperphagia
| Article | Year |
|---|---|
Serotonergic and histaminergic mechanisms involved in intralipid drinking?
Topics: Aminopyridines; Animals; Cyproheptadine; Dietary Fats; Dose-Response Relationship, Drug; Drinking Be | 2003 |