Page last updated: 2024-10-25

cyproheptadine and Hives

cyproheptadine has been researched along with Hives in 76 studies

Cyproheptadine: A serotonin antagonist and a histamine H1 blocker used as antipruritic, appetite stimulant, antiallergic, and for the post-gastrectomy dumping syndrome, etc.
cyproheptadine : The product resulting from the formal oxidative coupling of position 5 of 5H-dibenzo[a,d]cycloheptene with position 4 of 1-methylpiperidine resulting in the formation of a double bond between the two fragments. It is a sedating antihistamine with antimuscarinic and calcium-channel blocking actions. It is used (particularly as the hydrochloride sesquihydrate) for the relief of allergic conditions including rhinitis, conjunctivitis due to inhalant allergens and foods, urticaria and angioedema, and in pruritic skin disorders. Unlike other antihistamines, it is also a seratonin receptor antagonist, making it useful in conditions such as vascular headache and anorexia.

Research Excerpts

ExcerptRelevanceReference
"Rupatadine, a novel nonsedating second-generation H1-antihistamine with antiplatelet-activating factor activity, has been used in the treatment of allergic rhinitis and urticaria in European countries since 2003."9.30Efficacy and safety of rupatadine in Japanese adult and adolescent patients with chronic spontaneous urticaria: A double-blind, randomized, multicenter, placebo-controlled clinical trial. ( Aoki, H; Hide, M; Suzuki, T; Tanaka, A, 2019)
"Rupatadine is effective and well tolerated in the relief of urticaria symptoms, improving quality of life over 6 weeks in children with CSU."9.22Rupatadine is effective in the treatment of chronic spontaneous urticaria in children aged 2-11 years. ( Barkai, L; Izquierdo, I; Maurer, M; Mezei, G; Mitha, E; Potter, P; Santamaría, E, 2016)
"Cetirizine is commonly used in the treatment of urticaria."9.19Clinical effectiveness and safety of cetirizine versus rupatadine in chronic spontaneous urticaria: a randomized, double-blind, 6-week trial. ( Dakhale, GN; Hiware, SK; Mahatme, MS; Mishra, DB; Mukhi, JI; Salve, AM; Shinde, AT, 2014)
" This responder analysis, using different response levels, shows that the efficacy of rupatadine 10 mg and 20 mg is significantly better as compared to placebo in the treatment of chronic urticaria patients."9.14The use of a responder analysis to identify clinically meaningful differences in chronic urticaria patients following placebo- controlled treatment with rupatadine 10 and 20 mg. ( Giménez-Arnau, A; Izquierdo, I; Maurer, M, 2009)
"After rupatadine treatment, 11 (52%) of 21 patients exhibited a complete response (ie, no urticaria lesions after ice cube provocation)."9.14Rupatadine and its effects on symptom control, stimulation time, and temperature thresholds in patients with acquired cold urticaria. ( Ferrán, M; Giménez-Arnau, A; Izquierdo, I; Maurer, M; Metz, M; Scholz, E, 2010)
"A double-blind, crossover trial with a new triprolidine derivative, acrivastine (BW 825C; 8 mg 3 times daily), cyproheptadine (4 mg 3 times daily) and placebo was carried out in 18 patients suffering from idiopathic cold urticaria."9.06Comparison of the new antihistamine acrivastine (BW 825C) versus cyproheptadine in the treatment of idiopathic cold urticaria. ( Fräki, JE; Gibson, JR; Neittaanmäki, H, 1988)
"Randomized double-blind trials using doxepin and several conventional antihistamines were carried out for treatment of patients with idiopathic cold urticaria."9.05Comparison of cinnarizine, cyproheptadine, doxepin, and hydroxyzine in treatment of idiopathic cold urticaria: usefulness of doxepin. ( Fräki, JE; Myöhänen, T; Neittaanmäki, H, 1984)
"Eight subjects with primary-acquired cold urticaria were treated with chlorpheniramine maleate, cyproheptadine hydrochloride, and placebo in a double-blind clinical trial."9.04Primary acquired cold urticaria. Double-blind comparative study of treatment with cyproheptadine, chlorpheniramine, and placebo. ( Ellis, EF; St Pierre, JP; Wanderer, AA, 1977)
"The effect and tolerance of a new antihistamine, HC 20-511, in daily doses of 2 and 4 mg was compared with cyproheptadine (Periactin) 8 mg daily in 50 cases of chronic urticaria."9.04Comparison of a new antihistamine HC 20-511 with cyproheptadine (Periactin) in chronic urticaria. ( Kuokkanen, K, 1977)
"This study evaluates the effectiveness and safety of rupatadine in chronic urticaria (CU) and acquired cold urticaria (ACU), through a systematic review of the literature."8.89Rupatadine for the treatment of urticaria. ( Calogiuri, GF; Delle Donne, P; Di Leo, E; Ferrannini, A; Nettis, E; Vacca, A, 2013)
"Histamine release in cold urticaria was studied before and after therapy with cyproheptadine to determine whether any effect upon histamine release could be distinguished from end-organ receptor-site blockade."7.66The role of cyproheptadine in the treatment of cold urticaria. ( Evans, R; Horakova, Z; Kaplan, AP; Ottesen, E; Sigler, RW, 1980)
"Levocetirizine was found to be more efficacious than rupatadine in CIU patients, but both drugs caused mild sedation."6.80Levocetirizine and rupatadine in chronic idiopathic urticaria. ( Badyal, DK; Johnson, M; Kwatra, G; Thomas, EA, 2015)
"Rupatadine is a better choice in CIU in comparison to levocetirizine due to better efficacy and safety profile."6.76Rupatadine and levocetirizine in chronic idiopathic urticaria: a comparative study of efficacy and safety. ( Ahmed, I; Goud, P; Jaida, J; Maiti, R; Palani, A; Raghavendra, BN, 2011)
"Chronic urticaria is one of the most common and disturbing cutaneous condition."6.73Rupatadine in the treatment of chronic idiopathic urticaria: a double-blind, randomized, placebo-controlled multicentre study. ( Arnaiz, E; Donado, E; Gimenez-Arnau, A; Ianosi, S; Izquierdo, I; Kaszuba, A; Malbran, A; Perez, I; Poop, G; Pujol, RM, 2007)
"Both of them showed good results in the treatment of cold urticaria with mild side effects."6.68Cold urticaria in Thai children: comparison between cyproheptadine and ketotifen in the treatment. ( Tuchinda, M; Vichyanond, P; Visitsunthorn, N, 1995)
"Loratadine is a new selective peripheral histamine H1-receptor antagonist, that is orally effective, long-acting, and devoid of significant central and autonomic nervous system activity."6.67Comparative effects of loratadine and terfenadine in the treatment of chronic idiopathic urticaria. ( Belaich, S; Bruttmann, G; DeGreef, H; Lachapelle, JM; Paul, E; Pedrali, P; Tennstedt, D, 1990)
"Rupatadine is indicated for the treatment of allergic rhinitis and urticaria."6.53Rupatadine: global safety evaluation in allergic rhinitis and urticaria. ( Bachert, C; González-Núñez, V; Mullol, J, 2016)
"Rupatadine, a novel nonsedating second-generation H1-antihistamine with antiplatelet-activating factor activity, has been used in the treatment of allergic rhinitis and urticaria in European countries since 2003."5.30Efficacy and safety of rupatadine in Japanese adult and adolescent patients with chronic spontaneous urticaria: A double-blind, randomized, multicenter, placebo-controlled clinical trial. ( Aoki, H; Hide, M; Suzuki, T; Tanaka, A, 2019)
"Rupatadine is effective and well tolerated in the relief of urticaria symptoms, improving quality of life over 6 weeks in children with CSU."5.22Rupatadine is effective in the treatment of chronic spontaneous urticaria in children aged 2-11 years. ( Barkai, L; Izquierdo, I; Maurer, M; Mezei, G; Mitha, E; Potter, P; Santamaría, E, 2016)
"Cetirizine is commonly used in the treatment of urticaria."5.19Clinical effectiveness and safety of cetirizine versus rupatadine in chronic spontaneous urticaria: a randomized, double-blind, 6-week trial. ( Dakhale, GN; Hiware, SK; Mahatme, MS; Mishra, DB; Mukhi, JI; Salve, AM; Shinde, AT, 2014)
" This responder analysis, using different response levels, shows that the efficacy of rupatadine 10 mg and 20 mg is significantly better as compared to placebo in the treatment of chronic urticaria patients."5.14The use of a responder analysis to identify clinically meaningful differences in chronic urticaria patients following placebo- controlled treatment with rupatadine 10 and 20 mg. ( Giménez-Arnau, A; Izquierdo, I; Maurer, M, 2009)
"After rupatadine treatment, 11 (52%) of 21 patients exhibited a complete response (ie, no urticaria lesions after ice cube provocation)."5.14Rupatadine and its effects on symptom control, stimulation time, and temperature thresholds in patients with acquired cold urticaria. ( Ferrán, M; Giménez-Arnau, A; Izquierdo, I; Maurer, M; Metz, M; Scholz, E, 2010)
"A double-blind, crossover trial with a new triprolidine derivative, acrivastine (BW 825C; 8 mg 3 times daily), cyproheptadine (4 mg 3 times daily) and placebo was carried out in 18 patients suffering from idiopathic cold urticaria."5.06Comparison of the new antihistamine acrivastine (BW 825C) versus cyproheptadine in the treatment of idiopathic cold urticaria. ( Fräki, JE; Gibson, JR; Neittaanmäki, H, 1988)
"Randomized double-blind trials using doxepin and several conventional antihistamines were carried out for treatment of patients with idiopathic cold urticaria."5.05Comparison of cinnarizine, cyproheptadine, doxepin, and hydroxyzine in treatment of idiopathic cold urticaria: usefulness of doxepin. ( Fräki, JE; Myöhänen, T; Neittaanmäki, H, 1984)
"The effect and tolerance of a new antihistamine, HC 20-511, in daily doses of 2 and 4 mg was compared with cyproheptadine (Periactin) 8 mg daily in 50 cases of chronic urticaria."5.04Comparison of a new antihistamine HC 20-511 with cyproheptadine (Periactin) in chronic urticaria. ( Kuokkanen, K, 1977)
"Eight subjects with primary-acquired cold urticaria were treated with chlorpheniramine maleate, cyproheptadine hydrochloride, and placebo in a double-blind clinical trial."5.04Primary acquired cold urticaria. Double-blind comparative study of treatment with cyproheptadine, chlorpheniramine, and placebo. ( Ellis, EF; St Pierre, JP; Wanderer, AA, 1977)
" Rupatadine, a molecule with intense antihistaminic activity and with antagonist PAF effects through its interaction with specific receptors, is indicated for the treatment of intermittent or persistent allergic rhinitis and urticaria."4.89Efficacy and safety of rupatadine for allergic rhino-conjunctivitis: a systematic review of randomized, double-blind, placebo-controlled studies with meta-analysis. ( Canonica, GW; Compalati, E, 2013)
"This study evaluates the effectiveness and safety of rupatadine in chronic urticaria (CU) and acquired cold urticaria (ACU), through a systematic review of the literature."4.89Rupatadine for the treatment of urticaria. ( Calogiuri, GF; Delle Donne, P; Di Leo, E; Ferrannini, A; Nettis, E; Vacca, A, 2013)
"The second-generation H1-receptor antagonists terfenadine, astemizole, loratadine, and cetirizine are important first-line drugs for the relief of symptoms in patients with allergic rhinoconjunctivitis or chronic urticaria and may eventually supplant the potentially sedating first-generation H1-receptor antagonists in the treatment of these disorders."4.78Recent advances in H1-receptor antagonist treatment. ( Simons, FE, 1990)
"Histamine release in cold urticaria was studied before and after therapy with cyproheptadine to determine whether any effect upon histamine release could be distinguished from end-organ receptor-site blockade."3.66The role of cyproheptadine in the treatment of cold urticaria. ( Evans, R; Horakova, Z; Kaplan, AP; Ottesen, E; Sigler, RW, 1980)
"Combined H1 (cyproheptadine) and H2 antihistamines (cimetidine) were tried in eight patients with chronic urticaria who were previously unresponsive to conventional anti-urticarial regimens, including type I antihistamines, hydroxyzine, ephedrine and corticosteroids."3.66Treatment of chronic idiopathic urticaria with combined H1 and H2 blockers. ( Kohler, PF; Phanuphak, P; Schocket, A, 1978)
"In a single patient with severe essential acquired cold urticaria, the following drug regimes were assessed: diphenhydramine, cyproheptadine, hydroxyzine, terbutaline, cimetidine, hydroxyzine plus cimetidine, and hydroxyzine plus terbutaline."3.66Treatment of cold urticaria. ( Highet, AS; Titterington, DM, 1979)
"Levocetirizine was found to be more efficacious than rupatadine in CIU patients, but both drugs caused mild sedation."2.80Levocetirizine and rupatadine in chronic idiopathic urticaria. ( Badyal, DK; Johnson, M; Kwatra, G; Thomas, EA, 2015)
"Rupatadine is a better choice in CIU in comparison to levocetirizine due to better efficacy and safety profile."2.76Rupatadine and levocetirizine in chronic idiopathic urticaria: a comparative study of efficacy and safety. ( Ahmed, I; Goud, P; Jaida, J; Maiti, R; Palani, A; Raghavendra, BN, 2011)
"Chronic urticaria is one of the most common and disturbing cutaneous condition."2.73Rupatadine in the treatment of chronic idiopathic urticaria: a double-blind, randomized, placebo-controlled multicentre study. ( Arnaiz, E; Donado, E; Gimenez-Arnau, A; Ianosi, S; Izquierdo, I; Kaszuba, A; Malbran, A; Perez, I; Poop, G; Pujol, RM, 2007)
"Both of them showed good results in the treatment of cold urticaria with mild side effects."2.68Cold urticaria in Thai children: comparison between cyproheptadine and ketotifen in the treatment. ( Tuchinda, M; Vichyanond, P; Visitsunthorn, N, 1995)
"Loratadine is a new selective peripheral histamine H1-receptor antagonist, that is orally effective, long-acting, and devoid of significant central and autonomic nervous system activity."2.67Comparative effects of loratadine and terfenadine in the treatment of chronic idiopathic urticaria. ( Belaich, S; Bruttmann, G; DeGreef, H; Lachapelle, JM; Paul, E; Pedrali, P; Tennstedt, D, 1990)
" One hour prior to dosing and 1, 2, 3, 4, 6, 8, 12, 16, 24, 28, 32, 36, 40, and 48 hours after dosing, histamine and saline were injected intradermally into opposite arms."2.66Effects of loratadine (SCH 29851) in suppression of histamine-induced skin wheals. ( Dyer, JG; Gural, R; Kassem, N; Robillard, N; Roman, I, 1988)
"Rupatadine is indicated for the treatment of allergic rhinitis and urticaria."2.53Rupatadine: global safety evaluation in allergic rhinitis and urticaria. ( Bachert, C; González-Núñez, V; Mullol, J, 2016)
"Rupatadine is a once-daily, non-sedating, selective and long-acting new drug with a strong antagonist activity towards both histamine H(1) receptors and platelet-activating factor receptors."2.43Rupatadine: pharmacological profile and its use in the treatment of allergic disorders. ( Picado, C, 2006)
"Loratadine is a long acting antihistamine which has a high selectivity for peripheral histamine H1-receptors and lacks the central nervous system depressant effects often associated with some of the older antihistamines."2.38Loratadine. A preliminary review of its pharmacodynamic properties and therapeutic efficacy. ( Clissold, SP; Goa, KL; Sorkin, EM, 1989)
"Cold contact urticaria is the second most common subtype of physical urticaria."1.42Temperature thresholds in assessment of the clinical course of acquired cold contact urticaria: a prospective observational one-year study. ( Carnero, L; Curto-Barredo, L; Giménez-Arnau, AM; Martinez-Escala, ME; Pujol, RM, 2015)
"Aquagenic urticaria is a rare form of physical urticaria characterized by small follicular wheals with an erythematous flare upon exposure to water."1.28Aquagenic urticaria. ( Crowe, MJ; Guin, JD; Parker, RK, 1992)

Research

Studies (76)

TimeframeStudies, this research(%)All Research%
pre-199043 (56.58)18.7374
1990's12 (15.79)18.2507
2000's7 (9.21)29.6817
2010's13 (17.11)24.3611
2020's1 (1.32)2.80

Authors

AuthorsStudies
Nieto, A1
Nieto, M1
Mazón, Á1
Hide, M1
Suzuki, T1
Tanaka, A1
Aoki, H1
Nettis, E2
Delle Donne, P2
Di Leo, E2
Calogiuri, GF1
Ferrannini, A1
Vacca, A2
Compalati, E1
Canonica, GW1
Dakhale, GN1
Shinde, AT1
Mahatme, MS1
Hiware, SK1
Mishra, DB1
Mukhi, JI1
Salve, AM1
Martinez-Escala, ME1
Curto-Barredo, L2
Carnero, L1
Pujol, RM2
Giménez-Arnau, AM1
Sharma, M1
Bennett, C1
Cohen, SN1
Carter, B1
Johnson, M1
Kwatra, G1
Badyal, DK1
Thomas, EA1
Abajian, M1
Krause, K1
Santamaria, E2
Izquierdo, I5
Church, MK1
Maurer, M6
Giménez-Arnau, A5
Potter, P1
Mitha, E1
Barkai, L1
Mezei, G1
González-Núñez, V1
Bachert, C2
Mullol, J2
Dueñas-Laita, A1
Ruiz-Muñoz, P1
Armentia, A1
Pinacho, F1
Martín-Armentia, B1
Cassano, N1
Foti, C1
Vena, GA1
Metz, M2
Scholz, E1
Ferrán, M1
Maiti, R1
Jaida, J1
Raghavendra, BN1
Goud, P1
Ahmed, I1
Palani, A1
BAILEY, IS1
GRUPPER, C1
KASLIWAL, RM1
SETHI, JP1
MATSUMURA, T1
KUROUME, Y1
TATENO, K1
TAKEUCHI, K1
TAKEUCHI, T1
YASUDA, T1
YOSHIDA, K1
MIYAMOTO, M1
KITAMURA, K1
TAKASE, Y1
MEGURIGAMI, T1
ABE, Y1
MAEDA, Y1
RISOLD, JC1
GRAYSON, LD1
SHAIR, HM1
Picado, C2
Keam, SJ1
Plosker, GL1
Ianosi, S1
Kaszuba, A1
Malbran, A1
Poop, G1
Donado, E1
Perez, I1
Arnaiz, E1
Bousquet, J1
Canonica, WG1
Kowalski, ML1
Martí-Guadaño, E1
Scadding, G1
Van Cauwenberge, P1
Sigler, RW1
Evans, R1
Horakova, Z1
Ottesen, E1
Kaplan, AP4
Harvey, RP1
Wegs, J1
Schocket, AL1
Ahmed, AR1
Moy, R1
Garafalo, J1
Katayama, I1
Doi, T1
Nishioka, K1
Maeyama, K1
Yamatodani, A1
Neumann, Y1
Neittaanmäki, H2
Myöhänen, T1
Fräki, JE2
Soter, NA3
Wasserman, SI2
Berman, BA1
Ross, RN1
Sly, RM1
Wozel, G1
Kleine-Natrop, HE1
Tkach, JR1
Visitsunthorn, N1
Tuchinda, M2
Vichyanond, P1
Bentley, B1
Valsecchi, R1
Rozzoni, M1
Sena, P1
Pansera, B1
Kuokkanen, K1
Phanuphak, P1
Schocket, A1
Kohler, PF1
Tindall, JP1
Wanderer, AA3
St Pierre, JP1
Ellis, EF2
Tarnick, M1
Sibbald, RG1
Eady, RA1
Kobza-Black, A1
Greaves, MW1
Highet, AS1
Titterington, DM1
Czarny, D1
Baraf, CS1
Visitsuntorn, N1
Arunyanark, N1
Kerdsomnuk, S1
Parker, RK1
Crowe, MJ1
Guin, JD1
Abu Shareeah, AM1
Belaich, S1
Bruttmann, G1
DeGreef, H1
Lachapelle, JM1
Paul, E1
Pedrali, P1
Tennstedt, D1
Simons, FE2
McMillan, JL1
Simons, KJ1
Kurtz, AS1
Clissold, SP1
Sorkin, EM1
Goa, KL1
Monroe, EW1
Fox, RW1
Green, AW1
Izuno, GT1
Bernstein, DI1
Pleskow, WW1
Willis, I1
Brigante, JR1
Gibson, JR1
Kassem, N1
Roman, I1
Gural, R1
Dyer, JG1
Robillard, N1
Grandel, KE1
Farr, RS1
Michaëlsson, G1
Fink, JN1
Simon, N1
Dobozy, A1
Hunyadi, J1
Korossy, S1
Doroszlay, J1
Munkácsi, A1
Dömötör, A1
May, K1

Reviews

15 reviews available for cyproheptadine and Hives

ArticleYear
The clinical evidence of second-generation H1-antihistamines in the treatment of allergic rhinitis and urticaria in children over 2 years with a special focus on rupatadine.
    Expert opinion on pharmacotherapy, 2021, Volume: 22, Issue:4

    Topics: Adult; Child; Child, Preschool; Cyproheptadine; Histamine H1 Antagonists; Humans; Rhinitis, Allergic

2021
Rupatadine for the treatment of urticaria.
    Expert opinion on pharmacotherapy, 2013, Volume: 14, Issue:13

    Topics: Animals; Cyproheptadine; Histamine Antagonists; Humans; Platelet Activating Factor; Urticaria

2013
Efficacy and safety of rupatadine for allergic rhino-conjunctivitis: a systematic review of randomized, double-blind, placebo-controlled studies with meta-analysis.
    Current medical research and opinion, 2013, Volume: 29, Issue:11

    Topics: Conjunctivitis, Allergic; Cyproheptadine; Histamine Antagonists; Humans; Platelet Activating Factor;

2013
H1-antihistamines for chronic spontaneous urticaria.
    The Cochrane database of systematic reviews, 2014, Nov-14, Issue:11

    Topics: Cetirizine; Cyproheptadine; Histamine H1 Antagonists; Humans; Hydroxyzine; Loratadine; Randomized Co

2014
Rupatadine: global safety evaluation in allergic rhinitis and urticaria.
    Expert opinion on drug safety, 2016, Volume: 15, Issue:10

    Topics: Animals; Anti-Allergic Agents; Blood-Brain Barrier; Cyproheptadine; Histamine H1 Antagonists; Humans

2016
Rupatadine for the treatment of allergic rhinitis and urticaria.
    Expert review of clinical immunology, 2011, Volume: 7, Issue:1

    Topics: Anti-Allergic Agents; Chronic Disease; Cyproheptadine; Histamine H1 Antagonists; Humans; Platelet Ac

2011
Rupatadine: pharmacological profile and its use in the treatment of allergic disorders.
    Expert opinion on pharmacotherapy, 2006, Volume: 7, Issue:14

    Topics: Adolescent; Adult; Animals; Cyproheptadine; Histamine H1 Antagonists; Humans; Psychomotor Performanc

2006
Rupatadine: a review of its use in the management of allergic disorders.
    Drugs, 2007, Volume: 67, Issue:3

    Topics: Adolescent; Adult; Aged; Animals; Anti-Allergic Agents; Cyproheptadine; Drug Interactions; Humans; H

2007
Rupatadine in allergic rhinitis and chronic urticaria.
    Allergy, 2008, Volume: 63 Suppl 87

    Topics: Adolescent; Animals; Anti-Allergic Agents; Child; Chronic Disease; Clinical Trials as Topic; Cyprohe

2008
Physical urticaria/angioedema: an experimental model of mast cell activation in humans.
    The Journal of allergy and clinical immunology, 1980, Volume: 66, Issue:5

    Topics: Angioedema; Body Temperature; Chemotactic Factors; Cyproheptadine; Hot Temperature; Humans; Hydroxyz

1980
Physical urticaria/angioedema as an experimental model of acute and chronic inflammation in human skin.
    Springer seminars in immunopathology, 1981, Volume: 4, Issue:1

    Topics: Acute Disease; Angioedema; Body Temperature; Chronic Disease; Cold Temperature; Cyproheptadine; Derm

1981
Recent advances in H1-receptor antagonist treatment.
    The Journal of allergy and clinical immunology, 1990, Volume: 86, Issue:6 Pt 2

    Topics: Astemizole; Benzhydryl Compounds; Benzimidazoles; Cetirizine; Cyproheptadine; Histamine H1 Antagonis

1990
Three new non-sedative antihistamines: worth keeping an eye open for.
    Drug and therapeutics bulletin, 1990, May-14, Volume: 28, Issue:10

    Topics: Cetirizine; Cyproheptadine; Histamine H1 Antagonists; Humans; Hydroxyzine; Loratadine; Rhinitis, All

1990
Loratadine. A preliminary review of its pharmacodynamic properties and therapeutic efficacy.
    Drugs, 1989, Volume: 37, Issue:1

    Topics: Animals; Common Cold; Cyproheptadine; Female; Humans; Loratadine; Male; Rhinitis, Allergic, Perennia

1989
Treatment of urticaria and physical allergy.
    Modern treatment, 1968, Volume: 5, Issue:5

    Topics: Cold Temperature; Cyproheptadine; Diet Therapy; Drug Hypersensitivity; Environmental Exposure; Food

1968

Trials

24 trials available for cyproheptadine and Hives

ArticleYear
Efficacy and safety of rupatadine in Japanese adult and adolescent patients with chronic spontaneous urticaria: A double-blind, randomized, multicenter, placebo-controlled clinical trial.
    Allergology international : official journal of the Japanese Society of Allergology, 2019, Volume: 68, Issue:1

    Topics: Adolescent; Adult; Anti-Allergic Agents; Asian People; Child; Chronic Disease; Cyproheptadine; Doubl

2019
Clinical effectiveness and safety of cetirizine versus rupatadine in chronic spontaneous urticaria: a randomized, double-blind, 6-week trial.
    International journal of dermatology, 2014, Volume: 53, Issue:5

    Topics: Adult; Cetirizine; Chronic Disease; Cyproheptadine; Double-Blind Method; Female; Histamine H1 Antago

2014
Levocetirizine and rupatadine in chronic idiopathic urticaria.
    International journal of dermatology, 2015, Volume: 54, Issue:10

    Topics: Adolescent; Adult; Aged; Cetirizine; Child; Chronic Disease; Cyproheptadine; Female; Histamine H1 An

2015
Rupatadine 20 mg and 40 mg are Effective in Reducing the Symptoms of Chronic Cold Urticaria.
    Acta dermato-venereologica, 2016, Volume: 96, Issue:1

    Topics: Adult; Aged; Chronic Disease; Cold Temperature; Cross-Over Studies; Cyproheptadine; Double-Blind Met

2016
Rupatadine is effective in the treatment of chronic spontaneous urticaria in children aged 2-11 years.
    Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology, 2016, Volume: 27, Issue:1

    Topics: Age Factors; Child; Child, Preschool; Chronic Disease; Cyproheptadine; Double-Blind Method; Female;

2016
Successful treatment of chronic drug-resistant urticaria with alprazolam.
    The Journal of allergy and clinical immunology, 2009, Volume: 123, Issue:2

    Topics: Alprazolam; Chronic Disease; Cyproheptadine; Humans; Platelet Membrane Glycoproteins; Receptors, G-P

2009
The use of a responder analysis to identify clinically meaningful differences in chronic urticaria patients following placebo- controlled treatment with rupatadine 10 and 20 mg.
    Journal of the European Academy of Dermatology and Venereology : JEADV, 2009, Volume: 23, Issue:9

    Topics: Adult; Chronic Disease; Cyproheptadine; Dose-Response Relationship, Drug; Female; Health Surveys; Hi

2009
Rupatadine and its effects on symptom control, stimulation time, and temperature thresholds in patients with acquired cold urticaria.
    Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2010, Volume: 104, Issue:1

    Topics: Adult; Cold Temperature; Cyproheptadine; Double-Blind Method; Environmental Exposure; Female; Histam

2010
Rupatadine and levocetirizine in chronic idiopathic urticaria: a comparative study of efficacy and safety.
    Journal of drugs in dermatology : JDD, 2011, Volume: 10, Issue:12

    Topics: Adolescent; Adult; Cetirizine; Child; Chronic Disease; Cyproheptadine; Female; Follow-Up Studies; Hi

2011
Rupatadine in the treatment of chronic idiopathic urticaria: a double-blind, randomized, placebo-controlled multicentre study.
    Allergy, 2007, Volume: 62, Issue:5

    Topics: Adolescent; Adult; Aged; Child; Chronic Disease; Cyproheptadine; Double-Blind Method; Female; Humans

2007
A controlled trial of therapy in chronic urticaria.
    The Journal of allergy and clinical immunology, 1981, Volume: 68, Issue:4

    Topics: Adult; Chlorpheniramine; Chronic Disease; Cimetidine; Clinical Trials as Topic; Cyproheptadine; Drug

1981
[Antihistaminic therapy of chronic urticaria. Results of a multicenter study with azatadine and terfenadine].
    Fortschritte der Medizin, 1984, Oct-11, Volume: 102, Issue:38

    Topics: Adult; Benzhydryl Compounds; Chronic Disease; Clinical Trials as Topic; Cyproheptadine; Female; Hist

1984
Comparison of cinnarizine, cyproheptadine, doxepin, and hydroxyzine in treatment of idiopathic cold urticaria: usefulness of doxepin.
    Journal of the American Academy of Dermatology, 1984, Volume: 11, Issue:3

    Topics: Adolescent; Adult; Cinnarizine; Cold Temperature; Cyproheptadine; Doxepin; Female; Humans; Hydroxyzi

1984
Cold urticaria in Thai children: comparison between cyproheptadine and ketotifen in the treatment.
    Asian Pacific journal of allergy and immunology, 1995, Volume: 13, Issue:1

    Topics: Anti-Allergic Agents; Child; Child, Preschool; Cold Temperature; Cross-Over Studies; Cyproheptadine;

1995
Comparison of a new antihistamine HC 20-511 with cyproheptadine (Periactin) in chronic urticaria.
    Acta allergologica, 1977, Volume: 32, Issue:5

    Topics: Adult; Clinical Trials as Topic; Cyproheptadine; Double-Blind Method; Drug Evaluation; Female; Hista

1977
Primary acquired cold urticaria. Double-blind comparative study of treatment with cyproheptadine, chlorpheniramine, and placebo.
    Archives of dermatology, 1977, Volume: 113, Issue:10

    Topics: Adolescent; Adult; Child; Chlorpheniramine; Clinical Trials as Topic; Cold Temperature; Cyproheptadi

1977
Treatment of pruritus in allergic dermatoses: an evaluation of the relative efficacy of cyproheptadine and hydroxyzine.
    Current therapeutic research, clinical and experimental, 1976, Volume: 19, Issue:1

    Topics: Adolescent; Adult; Aged; Clinical Trials as Topic; Cyproheptadine; Dermatitis, Atopic; Dermatitis, C

1976
Comparative efficacy of loratadine and terfenadine in the treatment of chronic idiopathic urticaria.
    International journal of dermatology, 1992, Volume: 31, Issue:5

    Topics: Adult; Chronic Disease; Cyproheptadine; Female; Histamine Antagonists; Humans; Loratadine; Male; Pru

1992
Comparative effects of loratadine and terfenadine in the treatment of chronic idiopathic urticaria.
    Annals of allergy, 1990, Volume: 64, Issue:2 Pt 2

    Topics: Adolescent; Adult; Aged; Benzhydryl Compounds; Chronic Disease; Clinical Trials as Topic; Cyprohepta

1990
A double-blind, single-dose, crossover comparison of cetirizine, terfenadine, loratadine, astemizole, and chlorpheniramine versus placebo: suppressive effects on histamine-induced wheals and flares during 24 hours in normal subjects.
    The Journal of allergy and clinical immunology, 1990, Volume: 86, Issue:4 Pt 1

    Topics: Adult; Astemizole; Benzhydryl Compounds; Benzimidazoles; Cetirizine; Chlorpheniramine; Cyproheptadin

1990
Efficacy and safety of loratadine (10 mg once daily) in the management of idiopathic chronic urticaria.
    Journal of the American Academy of Dermatology, 1988, Volume: 19, Issue:1 Pt 1

    Topics: Chronic Disease; Clinical Trials as Topic; Cyproheptadine; Double-Blind Method; Histamine H1 Antagon

1988
Comparison of the new antihistamine acrivastine (BW 825C) versus cyproheptadine in the treatment of idiopathic cold urticaria.
    Dermatologica, 1988, Volume: 177, Issue:2

    Topics: Adult; Clinical Trials as Topic; Cold Temperature; Cyproheptadine; Double-Blind Method; Female; Hist

1988
Effects of loratadine (SCH 29851) in suppression of histamine-induced skin wheals.
    Annals of allergy, 1988, Volume: 60, Issue:6

    Topics: Adolescent; Adult; Clinical Trials as Topic; Cyproheptadine; Dose-Response Relationship, Drug; Hista

1988
Evaluation of peritol in the management of allergic diseases of the skin.
    Therapia Hungarica (English edition), 1972, Volume: 20, Issue:3

    Topics: Acetylcholine; Body Weight; Clinical Trials as Topic; Cyproheptadine; Dermatitis, Atopic; Eczema; Hi

1972

Other Studies

37 other studies available for cyproheptadine and Hives

ArticleYear
Temperature thresholds in assessment of the clinical course of acquired cold contact urticaria: a prospective observational one-year study.
    Acta dermato-venereologica, 2015, Volume: 95, Issue:3

    Topics: Adult; Algorithms; Cold Temperature; Critical Pathways; Cyproheptadine; Female; Histamine H1 Antagon

2015
Treatment of acquired cold urticaria with rupatadine.
    Allergy, 2009, Volume: 64, Issue:9

    Topics: Adult; Chronic Disease; Cold Temperature; Cyproheptadine; Female; Humans; Middle Aged; Platelet Acti

2009
Cyproheptadine in treatment of urticaria.
    British medical journal, 1961, Aug-12, Volume: 2, Issue:5249

    Topics: Anti-Allergic Agents; Cyproheptadine; Histamine H1 Antagonists; Serotonin; Serotonin Antagonists; Ur

1961
[Cypro-heptadine hydrochloride in the treatment of pigmentary urticaria and cutaneous mastocytosis].
    Clinique (Paris, France), 1963, Volume: 58

    Topics: Biological Products; Cyproheptadine; Humans; Mast Cells; Mastocytosis, Cutaneous; Urticaria

1963
CLINICAL EVALUATION OF A NEW DRUG CYPROHEPTADINE IN ALLERGIC DERMATOSIS.
    The Journal of the Association of Physicians of India, 1964, Volume: 12

    Topics: Cyproheptadine; Dermatitis; Dermatitis, Atopic; Dermatitis, Contact; Drug Eruptions; Humans; Neurode

1964
[ON THE THERAPEUTIC EFFECT OF SEROTONIN INHIBITORS ON ALLERGIC DISEASES IN CHILDREN].
    Arerugi = [Allergy], 1964, Volume: 13

    Topics: Adolescent; Asthma; Bronchitis; Child; Common Cold; Cyproheptadine; Dermatology; Eczema; Exanthema;

1964
[ON THE EFFECT OF PERIACTIN ON CHRONIC URTICARIA AND VARIOUS SKIN TESTS].
    Arerugi = [Allergy], 1964, Volume: 13

    Topics: Chronic Disease; Cyproheptadine; Erythema; Humans; Pharmacology; Serotonin; Skin Tests; Urticaria

1964
[ON THE EFFECTIVENESS OF PERIACTIN IN URTICARIA].
    Arerugi = [Allergy], 1964, Volume: 13

    Topics: Cyproheptadine; Humans; Serotonin; Urticaria

1964
[EFFECTIVENESS OF SEROTONIN INHIBITORS IN VARIOUS SKIN DISEASES].
    Arerugi = [Allergy], 1964, Volume: 13

    Topics: Adolescent; Child; Cyproheptadine; Dermatology; Eczema; Erythema; Exanthema; Humans; Infant; Mouth;

1964
[INITIAL RESULTS OF THE ACTION OF A DRUG COMBINING CYPROHEPTADINE CHLORIDE AND DEXAMETHASONE ON INFLAMMATORY AND ALLERGIC DERMATOSES].
    La Revue lyonnaise de medecine, 1965, Feb-28, Volume: 14

    Topics: Adolescent; Cyproheptadine; Dermatitis; Dermatitis, Atopic; Dermatitis, Contact; Dexamethasone; Drug

1965
USE OF CYPROHEPTADINE AND CYPROHEPTADINE-DEXAMETHASONE COMBINATION IN DERMATOLOGIC DISORDERS.
    Clinical medicine (Northfield, Ill.), 1964, Volume: 71

    Topics: Cyproheptadine; Dermatitis; Dermatitis Herpetiformis; Dermatitis, Atopic; Dermatitis, Contact; Dexam

1964
The role of cyproheptadine in the treatment of cold urticaria.
    The Journal of allergy and clinical immunology, 1980, Volume: 65, Issue:4

    Topics: Cold Temperature; Cyproheptadine; Female; Histamine; Histamine H1 Antagonists; Humans; Male; Urticar

1980
Treatment of acquired cold urticaria with azatadine.
    The Australasian journal of dermatology, 1981, Volume: 22, Issue:2

    Topics: Adolescent; Adult; Cold Temperature; Cyproheptadine; Female; Histamine H1 Antagonists; Humans; Male;

1981
Histamine release and therapy of severe dermatographism.
    The Journal of allergy and clinical immunology, 1981, Volume: 68, Issue:2

    Topics: Adolescent; Animals; Cyproheptadine; Diphenhydramine; Female; Histamine; Histamine Release; Humans;

1981
Acquired cold urticaria: H1 and H2 antagonists versus cold induced histamine release.
    The Journal of dermatology, 1983, Volume: 10, Issue:4

    Topics: Adult; Cimetidine; Cold Temperature; Cyproheptadine; Female; Histamine Release; Humans; Male; Urtica

1983
Exercise-induced hives.
    The Journal of allergy and clinical immunology, 1984, Volume: 73, Issue:5 Pt 2

    Topics: Cimetidine; Cold Temperature; Cyproheptadine; Histamine; Humans; Hydroxyzine; Hypotension; Methachol

1984
Urticaria.
    Cutis, 1982, Volume: 30, Issue:6

    Topics: Allergens; Cimetidine; Cyproheptadine; Humans; Hydroxyzine; Urticaria

1982
[Therapy of cold urticaria with cyproheptadine (pizotifene) (author's transl)].
    Dermatologische Monatschrift, 1981, Volume: 167, Issue:1

    Topics: Adolescent; Adult; Cold Temperature; Cyproheptadine; Female; Humans; Middle Aged; Urticaria

1981
Aquagenic urticaria.
    Cutis, 1981, Volume: 28, Issue:4

    Topics: Adult; Cyproheptadine; Female; Humans; Osmotic Pressure; Urticaria; Water

1981
Cold-induced urticaria and angioedema: diagnosis and management.
    The American journal of emergency medicine, 1993, Volume: 11, Issue:1

    Topics: Adult; Angioedema; Cold Temperature; Cyproheptadine; Female; Humans; Male; Urticaria

1993
Cold urticaria and delayed pressure urticaria in the same patient.
    Acta dermato-venereologica, 1996, Volume: 76, Issue:1

    Topics: Anti-Allergic Agents; Cold Temperature; Cyproheptadine; Dapsone; Female; Folic Acid Antagonists; Hum

1996
Treatment of chronic idiopathic urticaria with combined H1 and H2 blockers.
    Clinical allergy, 1978, Volume: 8, Issue:5

    Topics: Adult; Chronic Disease; Cimetidine; Cyproheptadine; Drug Therapy, Combination; Female; Histamine H1

1978
Relieving localized and generalized pruritus.
    Geriatrics, 1975, Volume: 30, Issue:3

    Topics: Aged; Bandages; Chlorpromazine; Cyproheptadine; Dermatitis; Dermatitis, Seborrheic; Female; Humans;

1975
[Results of the treatment in cases of cold urticaria, cold pruritus and cold rhinitis with peritol (zyproheptadinhydrochlorid) (author's transl)].
    Dermatologische Monatschrift, 1979, Volume: 165, Issue:4

    Topics: Cold Temperature; Cyproheptadine; Humans; Pruritus; Rhinitis, Allergic, Seasonal; Urticaria

1979
Cold urticaria and complement C2 deficiency.
    The British journal of dermatology, 1979, Volume: 101 Suppl 17

    Topics: Adult; Cold Temperature; Complement C2; Cyproheptadine; Female; Humans; Urticaria

1979
Treatment of cold urticaria.
    The British journal of dermatology, 1979, Volume: 101, Issue:1

    Topics: Adult; Cimetidine; Cold Temperature; Cyproheptadine; Diphenhydramine; Drug Therapy, Combination; Hum

1979
Urticaria and angio-oedema.
    The Medical journal of Australia, 1978, Dec-02, Volume: 2, Issue:6 Suppl

    Topics: Acute Disease; Angioedema; Chronic Disease; Cyproheptadine; Humans; Hydroxyzine; Urticaria

1978
Ice cube test in children with cold urticaria.
    Asian Pacific journal of allergy and immunology, 1992, Volume: 10, Issue:2

    Topics: Child; Child, Preschool; Chronic Disease; Cold Temperature; Cyproheptadine; False Positive Reactions

1992
Aquagenic urticaria.
    Cutis, 1992, Volume: 50, Issue:4

    Topics: Child; Combined Modality Therapy; Cyproheptadine; Humans; Hydroxyzine; Male; Parasympathetic Nervous

1992
Treatment of urticaria and angioedema: low-sedating H1-type antihistamines.
    Journal of the American Academy of Dermatology, 1991, Volume: 24, Issue:6 Pt 2

    Topics: Angioedema; Astemizole; Benzhydryl Compounds; Benzimidazoles; Cetirizine; Cyproheptadine; Histamine

1991
Regional expression of cold urticaria.
    The Journal of allergy and clinical immunology, 1990, Volume: 86, Issue:2

    Topics: Cold Temperature; Cyproheptadine; Head; Humans; Male; Middle Aged; Urticaria

1990
Clinical characteristics of cold-induced systemic reactions in acquired cold urticaria syndromes: recommendations for prevention of this complication and a proposal for a diagnostic classification of cold urticaria.
    The Journal of allergy and clinical immunology, 1986, Volume: 78, Issue:3 Pt 1

    Topics: Adolescent; Adult; Child; Child, Preschool; Cold Temperature; Cyproheptadine; Doxepin; Female; Human

1986
Effects of antihistamines, acetylsalicylic acid and prednisone on cutaneous reactions to kallikrein and prostaglandin E1.
    Acta dermato-venereologica, 1970, Volume: 50, Issue:1

    Topics: Adult; Aspirin; Bradykinin; Chronic Disease; Cyproheptadine; Drug Hypersensitivity; Eczema; Female;

1970
[Studies on the strength of antihistaminic drugs in urticaria factitia patients using the dermographia test].
    Berufs-Dermatosen, 1972, Volume: 20, Issue:3

    Topics: Cyproheptadine; Histamine; Histamine H1 Antagonists; Humans; Promethazine; Skin Tests; Urticaria

1972
Treatment of urticaria (hives) caused by cold.
    Eye, ear, nose & throat monthly, 1972, Volume: 51, Issue:5

    Topics: Cold Temperature; Cyproheptadine; Humans; Urticaria

1972
Treatment of cold urticaria with cyproheptadine.
    The Journal of allergy and clinical immunology, 1971, Volume: 48, Issue:6

    Topics: Adolescent; Adult; Child; Cold Temperature; Cyproheptadine; Female; Humans; Male; Urticaria

1971
[Periactin (cyproheptadin) in treatment of chronic urticaria].
    Polski tygodnik lekarski (Warsaw, Poland : 1960), 1965, Jun-28, Volume: 20, Issue:26

    Topics: Adolescent; Adult; Aged; Cyproheptadine; Female; Humans; Male; Middle Aged; Urticaria

1965