cyproheptadine has been researched along with Hepatocellular Carcinoma in 4 studies
Cyproheptadine: A serotonin antagonist and a histamine H1 blocker used as antipruritic, appetite stimulant, antiallergic, and for the post-gastrectomy dumping syndrome, etc.
cyproheptadine : The product resulting from the formal oxidative coupling of position 5 of 5H-dibenzo[a,d]cycloheptene with position 4 of 1-methylpiperidine resulting in the formation of a double bond between the two fragments. It is a sedating antihistamine with antimuscarinic and calcium-channel blocking actions. It is used (particularly as the hydrochloride sesquihydrate) for the relief of allergic conditions including rhinitis, conjunctivitis due to inhalant allergens and foods, urticaria and angioedema, and in pruritic skin disorders. Unlike other antihistamines, it is also a seratonin receptor antagonist, making it useful in conditions such as vascular headache and anorexia.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We reported two cases of hepatocellular carcinoma (HCC) with lung metastases who were treated with a combination of thalidomide and cyproheptadine." | 7.78 | Unexpected remission of hepatocellular carcinoma (HCC) with lung metastasis to the combination therapy of thalidomide and cyproheptadine: report of two cases and a preliminary HCC cell line study. ( Chen, SC; Feng, CW; Feng, YM; Hsu, CD, 2012) |
| "Cyproheptadine may significantly improve survival outcomes of sorafenib-treated advanced hepatocellular carcinoma patients." | 3.81 | Cyproheptadine significantly improves the overall and progression-free survival of sorafenib-treated advanced HCC patients. ( Chen, CY; Chen, SC; Feng, CW; Feng, YM; Lee, MY; Lu, CL, 2015) |
| "We reported two cases of hepatocellular carcinoma (HCC) with lung metastases who were treated with a combination of thalidomide and cyproheptadine." | 3.78 | Unexpected remission of hepatocellular carcinoma (HCC) with lung metastasis to the combination therapy of thalidomide and cyproheptadine: report of two cases and a preliminary HCC cell line study. ( Chen, SC; Feng, CW; Feng, YM; Hsu, CD, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (25.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (75.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Feng, YM | 3 |
| Feng, CW | 3 |
| Lu, CL | 1 |
| Lee, MY | 1 |
| Chen, CY | 1 |
| Chen, SC | 2 |
| Chen, SY | 1 |
| Hsieh, HY | 1 |
| Chen, YH | 1 |
| Hsu, CD | 2 |
| CATER, DB | 1 |
| SCHOENIGER, EL | 1 |
| WATKINSON, DA | 1 |
4 other studies available for cyproheptadine and Hepatocellular Carcinoma
| Article | Year |
|---|---|
Cyproheptadine significantly improves the overall and progression-free survival of sorafenib-treated advanced HCC patients.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellular; Case-Control | 2015 |
Cyproheptadine, an antihistaminic drug, inhibits proliferation of hepatocellular carcinoma cells by blocking cell cycle progression through the activation of P38 MAP kinase.
Topics: Carcinoma, Hepatocellular; Cell Cycle; Cell Cycle Checkpoints; Cell Proliferation; Cells, Cultured; | 2015 |
Unexpected remission of hepatocellular carcinoma (HCC) with lung metastasis to the combination therapy of thalidomide and cyproheptadine: report of two cases and a preliminary HCC cell line study.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellular; Cell Survival; Cyprohepta | 2012 |
EFFECT OF BREATHING HIGH PRESSURE OXYGEN UPON TISSUE OXYGEN TENSION IN RAT AND MOUSE TUMOURS.
Topics: Animals; Carcinoma, Hepatocellular; Cyproheptadine; Hypoxia; Liver Neoplasms; Mammary Neoplasms, Ani | 1963 |