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cyproheptadine and Fasting Hypoglycemia

cyproheptadine has been researched along with Fasting Hypoglycemia in 10 studies

Cyproheptadine: A serotonin antagonist and a histamine H1 blocker used as antipruritic, appetite stimulant, antiallergic, and for the post-gastrectomy dumping syndrome, etc.
cyproheptadine : The product resulting from the formal oxidative coupling of position 5 of 5H-dibenzo[a,d]cycloheptene with position 4 of 1-methylpiperidine resulting in the formation of a double bond between the two fragments. It is a sedating antihistamine with antimuscarinic and calcium-channel blocking actions. It is used (particularly as the hydrochloride sesquihydrate) for the relief of allergic conditions including rhinitis, conjunctivitis due to inhalant allergens and foods, urticaria and angioedema, and in pruritic skin disorders. Unlike other antihistamines, it is also a seratonin receptor antagonist, making it useful in conditions such as vascular headache and anorexia.

Fasting Hypoglycemia: HYPOGLYCEMIA expressed in the postabsorptive state, after prolonged FASTING, or an overnight fast.

Research Excerpts

ExcerptRelevanceReference
" After administration of cyproheptadine (16 mg daily, for two days) the glucagon responses to arginine (N=12) and to insulin-induced hypoglycemia (N=9) were more marked than in the control experiments (differences between maximal elevations: +165 pg/ml, P less than 0."3.65Potentiation of glucagon secretion by serotonin antagonists in man. ( Calle, C; Hedo, JA; Marco, J; Martinell, J; Villanueva, ML, 1976)
"Severe hypoglycemia and increased deaths were observed among two strains of endotoxin-poisoned mice within 3 to 6 hr after tryptophan injection."3.65Carbohydrate metabolism and survival of endotoxin-poisoned mice given tryptophan. ( Moon, RJ, 1972)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19909 (90.00)18.7374
1990's1 (10.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Slavnov, VN2
Valueva, GV1
Luchitskiĭ, EV2
Nathan, RS1
Tabrizi, MA1
Halpern, FS1
Sachar, EJ1
Kletzky, OA1
Marrs, RP1
Nicoloff, JT1
Marco, J1
Hedo, JA1
Martinell, J1
Calle, C1
Villanueva, ML1
Feldman, JM3
Plonk, JW2
Bivens, CH3
Moon, RJ1
Smythe, GA1
Lazarus, L1
Lebovitz, HE1

Trials

1 trial available for cyproheptadine and Fasting Hypoglycemia

ArticleYear
Suppression of human growth hormone secretion by melatonin and cyproheptadine.
    The Journal of clinical investigation, 1974, Volume: 54, Issue:1

    Topics: Adult; Blood Glucose; Brain; Brain Chemistry; Clinical Trials as Topic; Cyproheptadine; Growth Hormo

1974

Other Studies

9 other studies available for cyproheptadine and Fasting Hypoglycemia

ArticleYear
[Dynamics of beta-lipotropin and beta-endorphin levels in Itsenko-Cushing disease patients being treated with the antiserotonin preparation cyproheptadine (peritol) and chloditan].
    Terapevticheskii arkhiv, 1984, Volume: 56, Issue:9

    Topics: Adolescent; Adrenocorticotropic Hormone; Adult; beta-Endorphin; beta-Lipotropin; Cushing Syndrome; C

1984
Effect of cyproheptadine and atropine on the diurnal prolactin responses to insulin-induced hypoglycemia in normal men.
    The Journal of clinical endocrinology and metabolism, 1980, Volume: 51, Issue:1

    Topics: Atropine; Circadian Rhythm; Cyproheptadine; Humans; Hypoglycemia; Insulin; Male; Prolactin

1980
Effects of cyproheptadine on insulin-induced hypoglycaemia secretion of PRL, GH and cortisol.
    Clinical endocrinology, 1980, Volume: 13, Issue:3

    Topics: Adult; Cyproheptadine; Female; Growth Hormone; Humans; Hydrocortisone; Hypoglycemia; Insulin; Male;

1980
Potentiation of glucagon secretion by serotonin antagonists in man.
    The Journal of clinical endocrinology and metabolism, 1976, Volume: 42, Issue:2

    Topics: Arginine; Cyproheptadine; Fenclonine; Glucagon; Humans; Hypoglycemia; Insulin; Methysergide; Seroton

1976
The role of cortisol and growth hormone in the counter-regulation of insulin-induced hypoglycemia.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 1975, Volume: 7, Issue:5

    Topics: Blood Glucose; Cyproheptadine; Growth Hormone; Humans; Hydrocortisone; Hypoglycemia; Insulin; Seroto

1975
[Changes in the secretion of the hormones of the hypothalamo-hypophyseo-adrenal system in Itsenko-Cushing disease under the influence of insulin-induced hypoglycemia and thyroliberin].
    Vrachebnoe delo, 1990, Issue:3

    Topics: Adolescent; Adrenocorticotropic Hormone; Adult; Cushing Syndrome; Cyproheptadine; Fasting; Humans; H

1990
Carbohydrate metabolism and survival of endotoxin-poisoned mice given tryptophan.
    Infection and immunity, 1972, Volume: 5, Issue:3

    Topics: Allopurinol; Animals; Blood Glucose; Carbohydrate Metabolism; Cyproheptadine; Drug Interactions; End

1972
Inhibition of hypoglycemia-induced growth hormone secretion by the serotonin antagonists cyproheptadine and methysergide.
    The New England journal of medicine, 1973, Aug-02, Volume: 289, Issue:5

    Topics: Adult; Blood Glucose; Cyproheptadine; Female; Growth Hormone; Humans; Hypoglycemia; Hypothalamus; In

1973
Inhibition of hypoglycemia-induced cortisol secretion by the serotonin antagonist cyproheptadine.
    The Journal of clinical endocrinology and metabolism, 1974, Volume: 38, Issue:5

    Topics: Binding, Competitive; Blood Glucose; Blood Proteins; Cyproheptadine; Female; Humans; Hydrocortisone;

1974