cyproheptadine has been researched along with Experimental Neoplasms in 5 studies
Cyproheptadine: A serotonin antagonist and a histamine H1 blocker used as antipruritic, appetite stimulant, antiallergic, and for the post-gastrectomy dumping syndrome, etc.
cyproheptadine : The product resulting from the formal oxidative coupling of position 5 of 5H-dibenzo[a,d]cycloheptene with position 4 of 1-methylpiperidine resulting in the formation of a double bond between the two fragments. It is a sedating antihistamine with antimuscarinic and calcium-channel blocking actions. It is used (particularly as the hydrochloride sesquihydrate) for the relief of allergic conditions including rhinitis, conjunctivitis due to inhalant allergens and foods, urticaria and angioedema, and in pruritic skin disorders. Unlike other antihistamines, it is also a seratonin receptor antagonist, making it useful in conditions such as vascular headache and anorexia.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Methysergide was also found to accelerate tumour cell proliferation, whereas cyproheptadine did not." | 1.26 | Evaluation of the cytotoxicity of dihydroxytryptamines and 5-hydroxytryptamine antagonists as cytotoxic agents in dimethylhydrazine-induced adenocarcinomata. ( Barkla, DH; Tutton, PJ, 1978) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (80.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| AATER, DB | 1 |
| PETRIE, C | 1 |
| WATKINSON, DA | 1 |
| Anderson, C | 1 |
| Hrabovsky, S | 1 |
| McKinley, Y | 1 |
| Tubesing, K | 1 |
| Tang, HP | 1 |
| Dunbar, R | 1 |
| Mukhtar, H | 1 |
| Elmets, CA | 1 |
| Tutton, PJ | 1 |
| Barkla, DH | 1 |
| Richelson, E | 1 |
| Hilgard, P | 1 |
| Heller, H | 1 |
| Schmidt, CG | 1 |
5 other studies available for cyproheptadine and Experimental Neoplasms
| Article | Year |
|---|---|
EFFECT OF 5-HYDROXYTRYPTAMINE AND CYPROHEPTADINE ON TUMOUR BLOOD FLOW; ESTIMATION BY RATE OF COOLING AFTER MICROWAVE DIATHERMY.
Topics: Animals; Blood Circulation; Cyproheptadine; Diathermy; Hyperthermia, Induced; Metabolism; Mice; Micr | 1965 |
Phthalocyanine photodynamic therapy: disparate effects of pharmacologic inhibitors on cutaneous photosensitivity and on tumor regression.
Topics: Animals; Anti-Inflammatory Agents; Antineoplastic Agents; Antipruritics; Cyproheptadine; Dexamethaso | 1997 |
Evaluation of the cytotoxicity of dihydroxytryptamines and 5-hydroxytryptamine antagonists as cytotoxic agents in dimethylhydrazine-induced adenocarcinomata.
Topics: 5,6-Dihydroxytryptamine; 5,7-Dihydroxytryptamine; Adenocarcinoma; Animals; Antineoplastic Agents; Cy | 1978 |
Tricyclic antidepressants and histamine H1 receptors.
Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Atropine; Benztropine; Cells, Cultured; Cl | 1979 |
The influence of platelet aggregation inhibitors on metastasis formation in mice (3LL).
Topics: Animals; Aspirin; Bencyclane; Cyproheptadine; Dipyridamole; Female; Lung Neoplasms; Male; Mice; Mice | 1976 |