cyproheptadine has been researched along with Eosinophilia, Pulmonary in 2 studies
Cyproheptadine: A serotonin antagonist and a histamine H1 blocker used as antipruritic, appetite stimulant, antiallergic, and for the post-gastrectomy dumping syndrome, etc.
cyproheptadine : The product resulting from the formal oxidative coupling of position 5 of 5H-dibenzo[a,d]cycloheptene with position 4 of 1-methylpiperidine resulting in the formation of a double bond between the two fragments. It is a sedating antihistamine with antimuscarinic and calcium-channel blocking actions. It is used (particularly as the hydrochloride sesquihydrate) for the relief of allergic conditions including rhinitis, conjunctivitis due to inhalant allergens and foods, urticaria and angioedema, and in pruritic skin disorders. Unlike other antihistamines, it is also a seratonin receptor antagonist, making it useful in conditions such as vascular headache and anorexia.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To determine whether oral administration of cyproheptadine or cetirizine blocks the action of serotonin and histamine, respectively, and results in diminished eosinophilic airway inflammation in cats with experimentally induced asthma." | 7.74 | Effects of cyproheptadine and cetirizine on eosinophilic airway inflammation in cats with experimentally induced asthma. ( Jiji, RD; McGee Turner, JB; Reinero, CR; Schooley, EK; Spinka, CM, 2007) |
| "To determine whether oral administration of cyproheptadine or cetirizine blocks the action of serotonin and histamine, respectively, and results in diminished eosinophilic airway inflammation in cats with experimentally induced asthma." | 3.74 | Effects of cyproheptadine and cetirizine on eosinophilic airway inflammation in cats with experimentally induced asthma. ( Jiji, RD; McGee Turner, JB; Reinero, CR; Schooley, EK; Spinka, CM, 2007) |
| "OVA-induced pulmonary eosinophilia in wild-type mice was significantly inhibited using CYP alone and maximally in combination with a CCR3 receptor antagonist." | 1.32 | Cutting edge: serotonin is a chemotactic factor for eosinophils and functions additively with eotaxin. ( Boehme, SA; Lavrador, K; Lio, FM; Pandit, TS; Rao, SP; Sikora, L; Sriramarao, P, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Boehme, SA | 1 |
| Lio, FM | 1 |
| Sikora, L | 1 |
| Pandit, TS | 1 |
| Lavrador, K | 1 |
| Rao, SP | 1 |
| Sriramarao, P | 1 |
| Schooley, EK | 1 |
| McGee Turner, JB | 1 |
| Jiji, RD | 1 |
| Spinka, CM | 1 |
| Reinero, CR | 1 |
2 other studies available for cyproheptadine and Eosinophilia, Pulmonary
| Article | Year |
|---|---|
Cutting edge: serotonin is a chemotactic factor for eosinophils and functions additively with eotaxin.
Topics: Adjuvants, Immunologic; Allergens; Cell Migration Inhibition; Chemokine CCL11; Chemokines, CC; Chemo | 2004 |
Effects of cyproheptadine and cetirizine on eosinophilic airway inflammation in cats with experimentally induced asthma.
Topics: Animals; Asthma; Bronchoalveolar Lavage Fluid; Cat Diseases; Cats; Cetirizine; Cross-Over Studies; C | 2007 |