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cyproheptadine and Endocrine System Diseases

cyproheptadine has been researched along with Endocrine System Diseases in 1 studies

Cyproheptadine: A serotonin antagonist and a histamine H1 blocker used as antipruritic, appetite stimulant, antiallergic, and for the post-gastrectomy dumping syndrome, etc.
cyproheptadine : The product resulting from the formal oxidative coupling of position 5 of 5H-dibenzo[a,d]cycloheptene with position 4 of 1-methylpiperidine resulting in the formation of a double bond between the two fragments. It is a sedating antihistamine with antimuscarinic and calcium-channel blocking actions. It is used (particularly as the hydrochloride sesquihydrate) for the relief of allergic conditions including rhinitis, conjunctivitis due to inhalant allergens and foods, urticaria and angioedema, and in pruritic skin disorders. Unlike other antihistamines, it is also a seratonin receptor antagonist, making it useful in conditions such as vascular headache and anorexia.

Endocrine System Diseases: Pathological processes of the ENDOCRINE GLANDS, and diseases resulting from abnormal level of available HORMONES.

Research Excerpts

ExcerptRelevanceReference
"Sixteen patients with metastatic neuroendocrine tumors and the malignant carcinoid syndrome were treated with cyproheptadine (Periactin, Merck, Sharp & Dohme, West Point, PA) at maximum tolerable doses that ranged from 12 to 48 mg daily."9.07A study of cyproheptadine in the treatment of metastatic carcinoid tumor and the malignant carcinoid syndrome. ( Kvols, LK; Moertel, CG; Rubin, J, 1991)
"Sixteen patients with metastatic neuroendocrine tumors and the malignant carcinoid syndrome were treated with cyproheptadine (Periactin, Merck, Sharp & Dohme, West Point, PA) at maximum tolerable doses that ranged from 12 to 48 mg daily."5.07A study of cyproheptadine in the treatment of metastatic carcinoid tumor and the malignant carcinoid syndrome. ( Kvols, LK; Moertel, CG; Rubin, J, 1991)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Moertel, CG1
Kvols, LK1
Rubin, J1

Trials

1 trial available for cyproheptadine and Endocrine System Diseases

ArticleYear
A study of cyproheptadine in the treatment of metastatic carcinoid tumor and the malignant carcinoid syndrome.
    Cancer, 1991, Jan-01, Volume: 67, Issue:1

    Topics: Adult; Aged; Carcinoid Tumor; Cyproheptadine; Endocrine System Diseases; Female; Humans; Male; Malig

1991