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cyproheptadine and Encephalopathy, Toxic

cyproheptadine has been researched along with Encephalopathy, Toxic in 2 studies

Cyproheptadine: A serotonin antagonist and a histamine H1 blocker used as antipruritic, appetite stimulant, antiallergic, and for the post-gastrectomy dumping syndrome, etc.
cyproheptadine : The product resulting from the formal oxidative coupling of position 5 of 5H-dibenzo[a,d]cycloheptene with position 4 of 1-methylpiperidine resulting in the formation of a double bond between the two fragments. It is a sedating antihistamine with antimuscarinic and calcium-channel blocking actions. It is used (particularly as the hydrochloride sesquihydrate) for the relief of allergic conditions including rhinitis, conjunctivitis due to inhalant allergens and foods, urticaria and angioedema, and in pruritic skin disorders. Unlike other antihistamines, it is also a seratonin receptor antagonist, making it useful in conditions such as vascular headache and anorexia.

Research Excerpts

ExcerptRelevanceReference
"Cyproheptadine is a cheap and safe drug that does not have significant interactions with antiretroviral drugs."2.48Potential benefits of cyproheptadine in HIV-positive patients under treatment with antiretroviral drugs including efavirenz. ( Dabaghzadeh, F; Dashti-Khavidaki, S; Ghaeli, P; Khalili, H, 2012)
"Pre-treatment with cyproheptadine also resulted in a decrease of other toxic symptoms associated with Boophone disticha."1.39Pre-treatment of BALB/c mice with a centrally acting serotonin antagonist (cyproheptadine) reduces mortality from Boophone disticha poisoning. ( Gadaga, LL; Mutseura, M; Tagwireyi, D, 2013)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Dabaghzadeh, F1
Khalili, H1
Ghaeli, P1
Dashti-Khavidaki, S1
Mutseura, M1
Tagwireyi, D1
Gadaga, LL1

Reviews

1 review available for cyproheptadine and Encephalopathy, Toxic

ArticleYear
Potential benefits of cyproheptadine in HIV-positive patients under treatment with antiretroviral drugs including efavirenz.
    Expert opinion on pharmacotherapy, 2012, Volume: 13, Issue:18

    Topics: Alkynes; Anti-HIV Agents; Benzoxazines; Cyclopropanes; Cyproheptadine; Drug Interactions; Evidence-B

2012

Other Studies

1 other study available for cyproheptadine and Encephalopathy, Toxic

ArticleYear
Pre-treatment of BALB/c mice with a centrally acting serotonin antagonist (cyproheptadine) reduces mortality from Boophone disticha poisoning.
    Clinical toxicology (Philadelphia, Pa.), 2013, Volume: 51, Issue:1

    Topics: Africa, Southern; Animals; Behavior, Animal; Cyproheptadine; Dose-Response Relationship, Drug; Embry

2013