Page last updated: 2024-10-25

cyproheptadine and Emesis

cyproheptadine has been researched along with Emesis in 11 studies

Cyproheptadine: A serotonin antagonist and a histamine H1 blocker used as antipruritic, appetite stimulant, antiallergic, and for the post-gastrectomy dumping syndrome, etc.
cyproheptadine : The product resulting from the formal oxidative coupling of position 5 of 5H-dibenzo[a,d]cycloheptene with position 4 of 1-methylpiperidine resulting in the formation of a double bond between the two fragments. It is a sedating antihistamine with antimuscarinic and calcium-channel blocking actions. It is used (particularly as the hydrochloride sesquihydrate) for the relief of allergic conditions including rhinitis, conjunctivitis due to inhalant allergens and foods, urticaria and angioedema, and in pruritic skin disorders. Unlike other antihistamines, it is also a seratonin receptor antagonist, making it useful in conditions such as vascular headache and anorexia.

Research Excerpts

ExcerptRelevanceReference
"To evaluate our experience using the antimigraine prophylactic drugs, amitriptyline and cyproheptadine, for the prophylactic management of cyclic vomiting syndrome (CVS) in children."7.69Effective prophylactic therapy for cyclic vomiting syndrome in children using amitriptyline or cyproheptadine. ( Andersen, JM; Lockhart, JR; Sugerman, KS; Weinberg, WA, 1997)
"Cyproheptadine was given orally 12 to 14 hours before and again immediately before cisplatin administration."6.67Evaluation of butorphanol and cyproheptadine for prevention of cisplatin-induced vomiting in dogs. ( Berg, J; Dennis, RA; L'Heureux, DA; Moore, AS; Rand, WM, 1994)
"This is a retrospective chart review of 39 patients less than three years of age who were prescribed cyproheptadine for feeding intolerance or vomiting and had follow-up information available."3.83A retrospective review of cyproheptadine for feeding intolerance in children less than three years of age: effects and side effects. ( Butler, DR; Kaul, A; Meinzen-Derr, J; Merhar, SL; Mukkada, VA; Pentiuk, SP, 2016)
"Patients with abdominal migraine may benefit from prophylactic treatment with propranolol or cyproheptadine."3.70Abdominal migraine: prophylactic treatment and follow-up. ( Lichtman, SN; Rhoads, JM; Ulshen, MH; Worawattanakul, M, 1999)
"To evaluate our experience using the antimigraine prophylactic drugs, amitriptyline and cyproheptadine, for the prophylactic management of cyclic vomiting syndrome (CVS) in children."3.69Effective prophylactic therapy for cyclic vomiting syndrome in children using amitriptyline or cyproheptadine. ( Andersen, JM; Lockhart, JR; Sugerman, KS; Weinberg, WA, 1997)
"Cyproheptadine was given orally 12 to 14 hours before and again immediately before cisplatin administration."2.67Evaluation of butorphanol and cyproheptadine for prevention of cisplatin-induced vomiting in dogs. ( Berg, J; Dennis, RA; L'Heureux, DA; Moore, AS; Rand, WM, 1994)
"A 27-year-old patient with severe migraine developed bilateral disk edema and retinal hemorrhages during a prolonged attack of his illness, lasting at least two months."1.26Bilateral retinal hemorrhages and disk edema in migraine. ( Victor, DI; Welch, RB, 1977)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19902 (18.18)18.7374
1990's4 (36.36)18.2507
2000's1 (9.09)29.6817
2010's4 (36.36)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Badihian, N1
Saneian, H1
Badihian, S1
Yaghini, O1
Sagar, RC1
Ford, AC1
Merhar, SL1
Pentiuk, SP1
Mukkada, VA1
Meinzen-Derr, J1
Kaul, A1
Butler, DR1
Li, BU1
Lefevre, F1
Chelimsky, GG1
Boles, RG1
Nelson, SP1
Lewis, DW1
Linder, SL1
Issenman, RM1
Rudolph, CD1
Liao, KY1
Chang, FY1
Wu, LT1
Wu, TC1
Moore, AS1
Rand, WM1
Berg, J1
L'Heureux, DA1
Dennis, RA1
Andersen, JM1
Sugerman, KS1
Lockhart, JR1
Weinberg, WA1
Worawattanakul, M1
Rhoads, JM1
Lichtman, SN1
Ulshen, MH1
Victor, DI1
Welch, RB1
Nyman, K1
Bergman, U1
Campos, MF1
Rodrigues F das, C1

Trials

2 trials available for cyproheptadine and Emesis

ArticleYear
Prophylactic Therapy of Cyclic Vomiting Syndrome in Children: Comparison of Amitriptyline and Cyproheptadine: A Randomized Clinical Trial.
    The American journal of gastroenterology, 2018, Volume: 113, Issue:1

    Topics: Adrenergic Uptake Inhibitors; Amitriptyline; Child; Child, Preschool; Cyproheptadine; Female; Humans

2018
Evaluation of butorphanol and cyproheptadine for prevention of cisplatin-induced vomiting in dogs.
    Journal of the American Veterinary Medical Association, 1994, Aug-01, Volume: 205, Issue:3

    Topics: Animals; Butorphanol; Cisplatin; Cyproheptadine; Dog Diseases; Dogs; Dose-Response Relationship, Dru

1994

Other Studies

9 other studies available for cyproheptadine and Emesis

ArticleYear
Cyclic Vomiting Syndrome: Randomized Controlled Trials Are also Needed in Adults.
    The American journal of gastroenterology, 2017, Volume: 112, Issue:11

    Topics: Adult; Amitriptyline; Child; Cyproheptadine; Humans; Randomized Controlled Trials as Topic; Vomiting

2017
A retrospective review of cyproheptadine for feeding intolerance in children less than three years of age: effects and side effects.
    Acta paediatrica (Oslo, Norway : 1992), 2016, Volume: 105, Issue:8

    Topics: Child, Preschool; Cholinergic Antagonists; Cyproheptadine; Feeding and Eating Disorders; Female; His

2016
North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition consensus statement on the diagnosis and management of cyclic vomiting syndrome.
    Journal of pediatric gastroenterology and nutrition, 2008, Volume: 47, Issue:3

    Topics: Age Factors; Amitriptyline; Child; Child, Preschool; Cyproheptadine; Female; Humans; Life Style; Mal

2008
Cyclic vomiting syndrome in Taiwanese children.
    Journal of the Formosan Medical Association = Taiwan yi zhi, 2011, Volume: 110, Issue:1

    Topics: Adolescent; Adrenergic beta-Antagonists; Adrenergic Uptake Inhibitors; Age of Onset; Amitriptyline;

2011
Effective prophylactic therapy for cyclic vomiting syndrome in children using amitriptyline or cyproheptadine.
    Pediatrics, 1997, Volume: 100, Issue:6

    Topics: Adolescent; Amitriptyline; Child; Child, Preschool; Cyproheptadine; Drug Therapy, Combination; Femal

1997
Abdominal migraine: prophylactic treatment and follow-up.
    Journal of pediatric gastroenterology and nutrition, 1999, Volume: 28, Issue:1

    Topics: Abdominal Pain; Adolescent; Child; Child, Preschool; Cyproheptadine; Female; Gastrointestinal Agents

1999
Bilateral retinal hemorrhages and disk edema in migraine.
    American journal of ophthalmology, 1977, Volume: 84, Issue:4

    Topics: Adult; Belladonna Alkaloids; Child; Cyproheptadine; Dihydroergotamine; Female; Fluorescein Angiograp

1977
[Severe adverse effect of the anti-allergy drug loratadine--warning against prolonged use of non-prescription drugs].
    Lakartidningen, 1992, Jun-17, Volume: 89, Issue:25

    Topics: Adolescent; Adolescent Behavior; Cyproheptadine; Dose-Response Relationship, Drug; Headache; Histami

1992
Rats and marmosets respond differently to serotonin agonists and antagonists.
    Psychopharmacology, 1987, Volume: 92, Issue:4

    Topics: Animals; Behavior, Animal; Callitrichinae; Cyproheptadine; Male; Metergoline; Methysergide; Motor Ac

1987