cyproheptadine has been researched along with Electrocardiogram QT Prolonged in 3 studies
Cyproheptadine: A serotonin antagonist and a histamine H1 blocker used as antipruritic, appetite stimulant, antiallergic, and for the post-gastrectomy dumping syndrome, etc.
cyproheptadine : The product resulting from the formal oxidative coupling of position 5 of 5H-dibenzo[a,d]cycloheptene with position 4 of 1-methylpiperidine resulting in the formation of a double bond between the two fragments. It is a sedating antihistamine with antimuscarinic and calcium-channel blocking actions. It is used (particularly as the hydrochloride sesquihydrate) for the relief of allergic conditions including rhinitis, conjunctivitis due to inhalant allergens and foods, urticaria and angioedema, and in pruritic skin disorders. Unlike other antihistamines, it is also a seratonin receptor antagonist, making it useful in conditions such as vascular headache and anorexia.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Täubel, J | 1 |
| Ferber, G | 1 |
| Fernandes, S | 1 |
| Santamaría, E | 1 |
| Izquierdo, I | 1 |
| Kobayashi, K | 1 |
| Omuro, N | 1 |
| Takahara, A | 1 |
| Fité-Mora, R | 1 |
1 trial available for cyproheptadine and Electrocardiogram QT Prolonged
| Article | Year |
|---|---|
Cardiac Safety of Rupatadine in a Single-Ascending-Dose and Multiple-Ascending-Dose Study in Healthy Japanese Subjects, Using Intensive Electrocardiogram Assessments-Comparison With the Previous White Caucasian Thorough QT Study.
Topics: Asian People; Cyproheptadine; Double-Blind Method; Electrocardiography; Food-Drug Interactions; Heal | 2018 |
2 other studies available for cyproheptadine and Electrocardiogram QT Prolonged
| Article | Year |
|---|---|
The conventional antihistamine drug cyproheptadine lacks QT-interval-prolonging action in halothane-anesthetized guinea pigs: comparison with hydroxyzine.
Topics: Action Potentials; Anesthesia; Animals; Cyproheptadine; Dose-Response Relationship, Drug; Electrocar | 2014 |
Torsade de pointes associated with rupatadine.
Topics: Cyproheptadine; Histamine H1 Antagonists; Humans; Long QT Syndrome; Platelet Activating Factor; Prod | 2009 |