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cyproheptadine and Dyskinesia, Medication-Induced

cyproheptadine has been researched along with Dyskinesia, Medication-Induced in 9 studies

Cyproheptadine: A serotonin antagonist and a histamine H1 blocker used as antipruritic, appetite stimulant, antiallergic, and for the post-gastrectomy dumping syndrome, etc.
cyproheptadine : The product resulting from the formal oxidative coupling of position 5 of 5H-dibenzo[a,d]cycloheptene with position 4 of 1-methylpiperidine resulting in the formation of a double bond between the two fragments. It is a sedating antihistamine with antimuscarinic and calcium-channel blocking actions. It is used (particularly as the hydrochloride sesquihydrate) for the relief of allergic conditions including rhinitis, conjunctivitis due to inhalant allergens and foods, urticaria and angioedema, and in pruritic skin disorders. Unlike other antihistamines, it is also a seratonin receptor antagonist, making it useful in conditions such as vascular headache and anorexia.

Research Excerpts

ExcerptRelevanceReference
"Cyproheptadine is a cheap, widely available anti-allergy drug with a broad receptor binding profile which resembles that of clozapine."1.34Cyproheptadine resembles clozapine in vivo following both acute and chronic administration in rats. ( Cole, JC; Cooper, GD; Goudie, AJ; Sumnall, HR, 2007)
"Deanol did not produce the anticipated elevation in choline levels postulated to be one mechanism of its action."1.26Deanol acetamidobenzoate (Deaner) in tardive dyskinesia. ( Fann, WE; Stafford, JR, 1977)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19908 (88.89)18.7374
1990's0 (0.00)18.2507
2000's1 (11.11)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Goudie, AJ1
Cooper, GD1
Cole, JC1
Sumnall, HR1
Ogawa, T1
Nagao, T2
Kashiwabara, K1
Fujiwara, Y1
Harada, T1
Otsuki, S2
Alphs, L1
Davis, JM1
Ohshimo, T1
Mitsunobu, K1
Sato, M1
Kurata, K1
Hosokawa, K1
Koshino, Y1
Gardos, G1
Cole, JO1
Stafford, JR1
Fann, WE1
Papavasilliou, PS1
Cotzias, GC1
McDowell, FH1
Rosal, VL1
Sheehan, PJ1
Korsgaard, S1
Gerlach, J1
Christensson, E1

Trials

2 trials available for cyproheptadine and Dyskinesia, Medication-Induced

ArticleYear
Pilot study of cyproheptadine (Periactin) in tardive dyskinesia [proceedings].
    Psychopharmacology bulletin, 1978, Volume: 14, Issue:2

    Topics: Adult; Aged; Clinical Trials as Topic; Cyproheptadine; Dyskinesia, Drug-Induced; Female; Humans; Mal

1978
Cyproheptadine in levodopa-induced dyskinesia in parkinsonism.
    Clinical pharmacology and therapeutics, 1978, Volume: 23, Issue:2

    Topics: Aged; Carbidopa; Cyproheptadine; Double-Blind Method; Drug Therapy, Combination; Dyskinesia, Drug-In

1978

Other Studies

7 other studies available for cyproheptadine and Dyskinesia, Medication-Induced

ArticleYear
Cyproheptadine resembles clozapine in vivo following both acute and chronic administration in rats.
    Journal of psychopharmacology (Oxford, England), 2007, Volume: 21, Issue:2

    Topics: Animals; Anti-Allergic Agents; Antipsychotic Agents; Clozapine; Conditioning, Operant; Cyproheptadin

2007
Tardive dyskinesia and neurotransmitters: effects of sodium valproate, cyproheptadine, oxypertine, hydroxyzine pamoate and Ca-hopantenate on monoamine metabolites, cyclic nucleotides and gamma-aminobutyric acid in human cerebrospinal fluid.
    Clinical therapeutics, 1984, Volume: 7 Spec No

    Topics: Adult; Aged; Cyclic AMP; Cyclic GMP; Cyproheptadine; Dyskinesia, Drug-Induced; Female; Homovanillic

1984
Noncatecholaminergic treatments of tardive dyskinesia.
    Journal of clinical psychopharmacology, 1982, Volume: 2, Issue:6

    Topics: Amantadine; Anti-Anxiety Agents; Benzodiazepines; Cyproheptadine; D-Ala(2),MePhe(4),Met(0)-ol-enkeph

1982
Cerebrospinal fluid monoamine metabolites and cyclic nucleotides in chronic schizophrenic patients with tardive dyskinesia or drug-induced tremor.
    Biological psychiatry, 1979, Volume: 14, Issue:3

    Topics: Adult; Chronic Disease; Cyclic AMP; Cyclic GMP; Cyproheptadine; Dyskinesia, Drug-Induced; Female; Ho

1979
Treatment of neuroleptic induced tardive dyskinesia with cyproheptadine.
    Journal of neurology, 1977, Jul-20, Volume: 215, Issue:4

    Topics: Adult; Aged; Cyproheptadine; Dyskinesia, Drug-Induced; Female; Humans; Male; Middle Aged; Tranquiliz

1977
Deanol acetamidobenzoate (Deaner) in tardive dyskinesia.
    Diseases of the nervous system, 1977, Volume: 38, Issue:12 Pt 2

    Topics: Choline; Cyproheptadine; Deanol; Drug Evaluation; Dyskinesia, Drug-Induced; Ethanolamines; Humans; M

1977
Behavioral aspects of serotonin-dopamine interaction in the monkey.
    European journal of pharmacology, 1985, Dec-03, Volume: 118, Issue:3

    Topics: Animals; Chlorocebus aethiops; Cyproheptadine; Dextroamphetamine; Dopamine; Dyskinesia, Drug-Induced

1985