cyproheptadine has been researched along with Drug Overdose in 8 studies
Cyproheptadine: A serotonin antagonist and a histamine H1 blocker used as antipruritic, appetite stimulant, antiallergic, and for the post-gastrectomy dumping syndrome, etc.
cyproheptadine : The product resulting from the formal oxidative coupling of position 5 of 5H-dibenzo[a,d]cycloheptene with position 4 of 1-methylpiperidine resulting in the formation of a double bond between the two fragments. It is a sedating antihistamine with antimuscarinic and calcium-channel blocking actions. It is used (particularly as the hydrochloride sesquihydrate) for the relief of allergic conditions including rhinitis, conjunctivitis due to inhalant allergens and foods, urticaria and angioedema, and in pruritic skin disorders. Unlike other antihistamines, it is also a seratonin receptor antagonist, making it useful in conditions such as vascular headache and anorexia.
Drug Overdose: Accidental or deliberate use of a medication or street drug in excess of normal dosage.
| Excerpt | Relevance | Reference |
|---|---|---|
| "She had a seizure and required sedation and intubation." | 5.62 | Two Cases of Serotonin Syndrome After Bupropion Overdose Treated With Cyproheptadine. ( Beau, J; Bolton, TA; Carpenter, JE; Kazzi, Z; Kiernan, EA; Murray, BP; Sayers, J; Wolf, MJ; Yeh, M, 2021) |
| "BACKGROUND Serotonin syndrome is a condition characterized predominantly by neuromuscular symptoms and altered thermoregulation in response to serotonergic overtone." | 5.48 | Delayed Serotonin Syndrome in the Setting of a Mixed Fluoxetine and Serotonin Antagonist Overdose. ( Lin, CM; Little, K; Reynolds, PM, 2018) |
| "She had a seizure and required sedation and intubation." | 1.62 | Two Cases of Serotonin Syndrome After Bupropion Overdose Treated With Cyproheptadine. ( Beau, J; Bolton, TA; Carpenter, JE; Kazzi, Z; Kiernan, EA; Murray, BP; Sayers, J; Wolf, MJ; Yeh, M, 2021) |
| "BACKGROUND Serotonin syndrome is a condition characterized predominantly by neuromuscular symptoms and altered thermoregulation in response to serotonergic overtone." | 1.48 | Delayed Serotonin Syndrome in the Setting of a Mixed Fluoxetine and Serotonin Antagonist Overdose. ( Lin, CM; Little, K; Reynolds, PM, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (25.00) | 18.2507 |
| 2000's | 3 (37.50) | 29.6817 |
| 2010's | 2 (25.00) | 24.3611 |
| 2020's | 1 (12.50) | 2.80 |
| Authors | Studies |
|---|---|
| Murray, BP | 1 |
| Carpenter, JE | 1 |
| Sayers, J | 1 |
| Yeh, M | 1 |
| Beau, J | 1 |
| Kiernan, EA | 1 |
| Wolf, MJ | 1 |
| Bolton, TA | 1 |
| Kazzi, Z | 1 |
| Little, K | 1 |
| Lin, CM | 1 |
| Reynolds, PM | 1 |
| Chu, FK | 1 |
| Yuan, CM | 1 |
| Spandorfer, PR | 1 |
| Miller, SL | 1 |
| Henretig, FM | 1 |
| Shaw, LM | 1 |
| Lee, AC | 1 |
| So, KT | 1 |
| Scott, J | 1 |
| Pache, D | 1 |
| Keane, G | 1 |
| Buckle, H | 1 |
| O'Brien, N | 1 |
| Blaustein, BS | 1 |
| Gaeta, TJ | 1 |
| Balentine, JR | 1 |
| Gindi, M | 1 |
| Horowitz, BZ | 1 |
| Mullins, ME | 1 |
8 other studies available for cyproheptadine and Drug Overdose
| Article | Year |
|---|---|
Two Cases of Serotonin Syndrome After Bupropion Overdose Treated With Cyproheptadine.
Topics: Adolescent; Adult; Bupropion; Cyproheptadine; Drug Overdose; Female; Humans; Male; Seizures; Seroton | 2021 |
Delayed Serotonin Syndrome in the Setting of a Mixed Fluoxetine and Serotonin Antagonist Overdose.
Topics: Benzodiazepines; Bupropion; Cyproheptadine; Dopamine Uptake Inhibitors; Drug Overdose; Fluoxetine; H | 2018 |
Review of the epidemiology and characteristics of intentional cyproheptadine overdose in Hong Kong.
Topics: Adolescent; Adult; Age Distribution; Child; Cyproheptadine; Delirium; Dose-Response Relationship, Dr | 2011 |
Evaluation of tricyclic antidepressant false positivity in a pediatric case of cyproheptadine (periactin) overdose.
Topics: Antidepressive Agents, Tricyclic; Child, Preschool; Chromatography, High Pressure Liquid; Cyprohepta | 2003 |
Acute anticholinergic poisoning in children.
Topics: Antidiarrheals; Atropine; Child; Cholinergic Antagonists; Colic; Cyproheptadine; Diphenoxylate; Drug | 2005 |
Prolonged anticholinergic delirium following antihistamine overdose.
Topics: Adolescent; Cholinergic Antagonists; Cyproheptadine; Cytochrome P-450 CYP2D6 Inhibitors; Delirium; D | 2007 |
Cyproheptadine-induced central anticholinergic syndrome in a child: a case report.
Topics: Adolescent; Cholinergic Antagonists; Confusion; Cyproheptadine; Drug Overdose; Feeding and Eating Di | 1995 |
Cyproheptadine for serotonin syndrome in an accidental pediatric sertraline ingestion.
Topics: Child, Preschool; Cyproheptadine; Drug Overdose; Female; Humans; Selective Serotonin Reuptake Inhibi | 1999 |