cyproheptadine has been researched along with Disseminated Intravascular Coagulation in 2 studies
Cyproheptadine: A serotonin antagonist and a histamine H1 blocker used as antipruritic, appetite stimulant, antiallergic, and for the post-gastrectomy dumping syndrome, etc.
cyproheptadine : The product resulting from the formal oxidative coupling of position 5 of 5H-dibenzo[a,d]cycloheptene with position 4 of 1-methylpiperidine resulting in the formation of a double bond between the two fragments. It is a sedating antihistamine with antimuscarinic and calcium-channel blocking actions. It is used (particularly as the hydrochloride sesquihydrate) for the relief of allergic conditions including rhinitis, conjunctivitis due to inhalant allergens and foods, urticaria and angioedema, and in pruritic skin disorders. Unlike other antihistamines, it is also a seratonin receptor antagonist, making it useful in conditions such as vascular headache and anorexia.
Disseminated Intravascular Coagulation: A disorder characterized by procoagulant substances entering the general circulation causing a systemic thrombotic process. The activation of the clotting mechanism may arise from any of a number of disorders. A majority of the patients manifest skin lesions, sometimes leading to PURPURA FULMINANS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Changes in the coagulation system typical of consumption reaction, microthrombosis in the lungs and other organs and haemodynamic disturbances caused by infusion of endotoxin in weaned pigs were prevented by treatment with the serotonin receptor antagonist cyproheptadine." | 7.67 | Influence of cyproheptadine on endotoxin-induced disseminated intravascular coagulation (DIC) in weaned pigs. ( Markwardt, F; Nowak, G, 1985) |
| "Changes in the coagulation system typical of consumption reaction, microthrombosis in the lungs and other organs and haemodynamic disturbances caused by infusion of endotoxin in weaned pigs were prevented by treatment with the serotonin receptor antagonist cyproheptadine." | 3.67 | Influence of cyproheptadine on endotoxin-induced disseminated intravascular coagulation (DIC) in weaned pigs. ( Markwardt, F; Nowak, G, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Demopoulos, C | 1 |
| Antonopoulou, S | 1 |
| Theoharides, TC | 1 |
| Nowak, G | 1 |
| Markwardt, F | 1 |
1 review available for cyproheptadine and Disseminated Intravascular Coagulation
| Article | Year |
|---|---|
COVID-19, microthromboses, inflammation, and platelet activating factor.
Topics: Antiviral Agents; Blood Platelets; COVID-19; Cyproheptadine; Disseminated Intravascular Coagulation; | 2020 |
1 other study available for cyproheptadine and Disseminated Intravascular Coagulation
| Article | Year |
|---|---|
Influence of cyproheptadine on endotoxin-induced disseminated intravascular coagulation (DIC) in weaned pigs.
Topics: Animals; Cyproheptadine; Disseminated Intravascular Coagulation; Endotoxins; Escherichia coli; Femal | 1985 |