cyproheptadine has been researched along with Diseases of Endocrine System in 1 studies
Cyproheptadine: A serotonin antagonist and a histamine H1 blocker used as antipruritic, appetite stimulant, antiallergic, and for the post-gastrectomy dumping syndrome, etc.
cyproheptadine : The product resulting from the formal oxidative coupling of position 5 of 5H-dibenzo[a,d]cycloheptene with position 4 of 1-methylpiperidine resulting in the formation of a double bond between the two fragments. It is a sedating antihistamine with antimuscarinic and calcium-channel blocking actions. It is used (particularly as the hydrochloride sesquihydrate) for the relief of allergic conditions including rhinitis, conjunctivitis due to inhalant allergens and foods, urticaria and angioedema, and in pruritic skin disorders. Unlike other antihistamines, it is also a seratonin receptor antagonist, making it useful in conditions such as vascular headache and anorexia.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Sixteen patients with metastatic neuroendocrine tumors and the malignant carcinoid syndrome were treated with cyproheptadine (Periactin, Merck, Sharp & Dohme, West Point, PA) at maximum tolerable doses that ranged from 12 to 48 mg daily." | 9.07 | A study of cyproheptadine in the treatment of metastatic carcinoid tumor and the malignant carcinoid syndrome. ( Kvols, LK; Moertel, CG; Rubin, J, 1991) |
| "Sixteen patients with metastatic neuroendocrine tumors and the malignant carcinoid syndrome were treated with cyproheptadine (Periactin, Merck, Sharp & Dohme, West Point, PA) at maximum tolerable doses that ranged from 12 to 48 mg daily." | 5.07 | A study of cyproheptadine in the treatment of metastatic carcinoid tumor and the malignant carcinoid syndrome. ( Kvols, LK; Moertel, CG; Rubin, J, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Moertel, CG | 1 |
| Kvols, LK | 1 |
| Rubin, J | 1 |
1 trial available for cyproheptadine and Diseases of Endocrine System
| Article | Year |
|---|---|
A study of cyproheptadine in the treatment of metastatic carcinoid tumor and the malignant carcinoid syndrome.
Topics: Adult; Aged; Carcinoid Tumor; Cyproheptadine; Endocrine System Diseases; Female; Humans; Male; Malig | 1991 |