cyproheptadine has been researched along with Disease Exacerbation in 3 studies
Cyproheptadine: A serotonin antagonist and a histamine H1 blocker used as antipruritic, appetite stimulant, antiallergic, and for the post-gastrectomy dumping syndrome, etc.
cyproheptadine : The product resulting from the formal oxidative coupling of position 5 of 5H-dibenzo[a,d]cycloheptene with position 4 of 1-methylpiperidine resulting in the formation of a double bond between the two fragments. It is a sedating antihistamine with antimuscarinic and calcium-channel blocking actions. It is used (particularly as the hydrochloride sesquihydrate) for the relief of allergic conditions including rhinitis, conjunctivitis due to inhalant allergens and foods, urticaria and angioedema, and in pruritic skin disorders. Unlike other antihistamines, it is also a seratonin receptor antagonist, making it useful in conditions such as vascular headache and anorexia.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To measure the reduction in nasal obstruction using acoustic rhinometry in patients with allergic rhinitis treated with rupatadine." | 5.14 | Reduction of nasal volume after allergen-induced rhinitis in patients treated with rupatadine: a randomized, cross-over, double-blind, placebo-controlled study. ( Bartrá, J; Izquierdo, I; Mullol, J; Muñoz-Cano, R; Picado, C; Serrano, C; Valero, A, 2009) |
| "Cyproheptadine may significantly improve survival outcomes of sorafenib-treated advanced hepatocellular carcinoma patients." | 3.81 | Cyproheptadine significantly improves the overall and progression-free survival of sorafenib-treated advanced HCC patients. ( Chen, CY; Chen, SC; Feng, CW; Feng, YM; Lee, MY; Lu, CL, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Sharma, N | 1 |
| Sankrityayan, H | 1 |
| Kale, A | 1 |
| Gaikwad, AB | 1 |
| Feng, YM | 1 |
| Feng, CW | 1 |
| Lu, CL | 1 |
| Lee, MY | 1 |
| Chen, CY | 1 |
| Chen, SC | 1 |
| Valero, A | 1 |
| Serrano, C | 1 |
| Bartrá, J | 1 |
| Izquierdo, I | 1 |
| Muñoz-Cano, R | 1 |
| Mullol, J | 1 |
| Picado, C | 1 |
1 trial available for cyproheptadine and Disease Exacerbation
| Article | Year |
|---|---|
Reduction of nasal volume after allergen-induced rhinitis in patients treated with rupatadine: a randomized, cross-over, double-blind, placebo-controlled study.
Topics: Administration, Intranasal; Adolescent; Adult; Anti-Allergic Agents; Cyproheptadine; Disease Progres | 2009 |
2 other studies available for cyproheptadine and Disease Exacerbation
| Article | Year |
|---|---|
Role of SET7/9 in the progression of ischemic renal injury in diabetic and non-diabetic rats.
Topics: Animals; Biomarkers; Cyproheptadine; Diabetes Mellitus, Experimental; Disease Progression; Histone-L | 2020 |
Cyproheptadine significantly improves the overall and progression-free survival of sorafenib-treated advanced HCC patients.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellular; Case-Control | 2015 |