cyproheptadine has been researched along with Depression, Endogenous in 18 studies
Cyproheptadine: A serotonin antagonist and a histamine H1 blocker used as antipruritic, appetite stimulant, antiallergic, and for the post-gastrectomy dumping syndrome, etc.
cyproheptadine : The product resulting from the formal oxidative coupling of position 5 of 5H-dibenzo[a,d]cycloheptene with position 4 of 1-methylpiperidine resulting in the formation of a double bond between the two fragments. It is a sedating antihistamine with antimuscarinic and calcium-channel blocking actions. It is used (particularly as the hydrochloride sesquihydrate) for the relief of allergic conditions including rhinitis, conjunctivitis due to inhalant allergens and foods, urticaria and angioedema, and in pruritic skin disorders. Unlike other antihistamines, it is also a seratonin receptor antagonist, making it useful in conditions such as vascular headache and anorexia.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The case of a young man with depressive illness who developed priapism while being treated with paroxetine is reported for the first time." | 7.69 | [Adverse effects: priapism caused by paroxetine]. ( Bertholon, F; el Allali, A; Krajewski, Y, 1996) |
| "The case of a young man with depressive illness who developed priapism while being treated with paroxetine is reported for the first time." | 3.69 | [Adverse effects: priapism caused by paroxetine]. ( Bertholon, F; el Allali, A; Krajewski, Y, 1996) |
| "Serotonin syndrome (SS) and neuroleptic malignant syndrome (NMS) are life-threatening adverse reactions caused by serotonergic antidepressants and neuroleptics, respectively." | 1.42 | Serotonin syndrome overlapping with neuroleptic malignant syndrome: A case report and approaches for differentially diagnosing the two syndromes. ( Nisijima, K, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (27.78) | 18.7374 |
| 1990's | 12 (66.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (5.56) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Nisijima, K | 1 |
| Bansal, S | 1 |
| Brown, WA | 1 |
| Christensen, RC | 1 |
| Bacher, NM | 1 |
| Sanzone, MM | 1 |
| Kaup, B | 1 |
| Arnott, S | 1 |
| Nutt, D | 1 |
| Katz, RJ | 1 |
| Rosenthal, M | 1 |
| Bertholon, F | 1 |
| Krajewski, Y | 1 |
| el Allali, A | 1 |
| Lauerma, H | 1 |
| Boon, F | 1 |
| Zubieta, JK | 1 |
| Demitrack, MA | 1 |
| Cohen, AJ | 1 |
| Feder, R | 1 |
| Sharpley, AL | 1 |
| Gregory, CA | 1 |
| Solomon, RA | 1 |
| Cowen, PJ | 1 |
| McCormick, S | 1 |
| Olin, J | 1 |
| Brotman, AW | 1 |
| Halmi, KA | 1 |
| Eckert, E | 1 |
| LaDu, TJ | 1 |
| Cohen, J | 1 |
| Kahn, DA | 1 |
| Riley, AJ | 1 |
| Riley, EJ | 1 |
| Decastro, RM | 1 |
3 trials available for cyproheptadine and Depression, Endogenous
| Article | Year |
|---|---|
Cyproheptadine in depression.
Topics: Adult; Aged; Clinical Trials as Topic; Cyproheptadine; Depressive Disorder; Humans; Male; Middle Age | 1983 |
Slow wave sleep and 5-HT2 receptor sensitivity during maintenance tricyclic antidepressant treatment.
Topics: Adult; Aged; Amitriptyline; Brain; Cyproheptadine; Depressive Disorder; Dothiepin; Double-Blind Meth | 1990 |
Anorexia nervosa. Treatment efficacy of cyproheptadine and amitriptyline.
Topics: Adolescent; Adult; Amitriptyline; Anorexia Nervosa; Body Weight; Clinical Trials as Topic; Cyprohept | 1986 |
15 other studies available for cyproheptadine and Depression, Endogenous
| Article | Year |
|---|---|
Serotonin syndrome overlapping with neuroleptic malignant syndrome: A case report and approaches for differentially diagnosing the two syndromes.
Topics: Antidepressive Agents, Tricyclic; Clinical Decision-Making; Cyproheptadine; Dantrolene; Depressive D | 2015 |
Adverse interaction of paroxetine and cyproheptadine.
Topics: Cyproheptadine; Depressive Disorder; Drug Interactions; Drug Therapy, Combination; Female; Humans; M | 1995 |
Cyproheptadine in treatment-resistant chronic schizophrenics with prior negative response to fluoxetine.
Topics: Adult; Aged; Antipsychotic Agents; Chronic Disease; Cyproheptadine; Depressive Disorder; Drug Therap | 1994 |
Successful treatment of fluvoxamine-induced anorgasmia by cyproheptadine.
Topics: Cyproheptadine; Depressive Disorder; Dose-Response Relationship, Drug; Drug Administration Schedule; | 1994 |
Adverse interaction of cyproheptadine with serotonergic antidepressants.
Topics: Acute Disease; Cyproheptadine; Depressive Disorder; Drug Interactions; Female; Fluoxetine; Humans; M | 1994 |
[Adverse effects: priapism caused by paroxetine].
Topics: Adult; Antidepressive Agents; Cyproheptadine; Depressive Disorder; Humans; Imipramine; Male; Paroxet | 1996 |
Successful treatment of citalopram-induced anorgasmia by cyproheptadine.
Topics: Antidepressive Agents; Citalopram; Cyproheptadine; Depressive Disorder; Dose-Response Relationship, | 1996 |
Cyproheptadine and SSRIs.
Topics: Adolescent; Cyproheptadine; Depressive Disorder; Drug Administration Schedule; Drug Interactions; Fe | 1999 |
Depression after cyproheptadine: MAO treatment.
Topics: Adult; Antidepressive Agents; Cyproheptadine; Depressive Disorder; Humans; Male; Phenelzine; Recurre | 1992 |
Fluoxetine-induced yawning and anorgasmia reversed by cyproheptadine treatment.
Topics: Cyproheptadine; Depressive Disorder; Fluoxetine; Humans; Male; Middle Aged; Orgasm; Sexual Dysfuncti | 1992 |
Reversal of antidepressant activity of fluoxetine by cyproheptadine in three patients.
Topics: Adult; Cyproheptadine; Depressive Disorder; Drug Interactions; Fluoxetine; Humans; Male; Middle Aged | 1991 |
Reversal of fluoxetine-induced anorgasmia by cyproheptadine in two patients.
Topics: Adult; Cyproheptadine; Depressive Disorder; Ejaculation; Fluoxetine; Humans; Male; Middle Aged; Orga | 1990 |
Possible toxic interaction between cyproheptadine and phenelzine.
Topics: Adult; Cyproheptadine; Depressive Disorder; Drug Interactions; Drug Therapy, Combination; Female; Ha | 1987 |
Cyproheptadine and antidepressant-induced anorgasmia.
Topics: Adult; Clomipramine; Cyproheptadine; Depressive Disorder; Female; Humans; Imipramine; Sexual Dysfunc | 1986 |
Reversal of MAOI-induced anorgasmia with cyproheptadine.
Topics: Adult; Cyproheptadine; Depressive Disorder; Female; Humans; Male; Monoamine Oxidase Inhibitors; Orga | 1985 |