Page last updated: 2024-10-25

cyproheptadine and Delirium

cyproheptadine has been researched along with Delirium in 3 studies

Cyproheptadine: A serotonin antagonist and a histamine H1 blocker used as antipruritic, appetite stimulant, antiallergic, and for the post-gastrectomy dumping syndrome, etc.
cyproheptadine : The product resulting from the formal oxidative coupling of position 5 of 5H-dibenzo[a,d]cycloheptene with position 4 of 1-methylpiperidine resulting in the formation of a double bond between the two fragments. It is a sedating antihistamine with antimuscarinic and calcium-channel blocking actions. It is used (particularly as the hydrochloride sesquihydrate) for the relief of allergic conditions including rhinitis, conjunctivitis due to inhalant allergens and foods, urticaria and angioedema, and in pruritic skin disorders. Unlike other antihistamines, it is also a seratonin receptor antagonist, making it useful in conditions such as vascular headache and anorexia.

Delirium: A disorder characterized by CONFUSION; inattentiveness; disorientation; ILLUSIONS; HALLUCINATIONS; agitation; and in some instances autonomic nervous system overactivity. It may result from toxic/metabolic conditions or structural brain lesions. (From Adams et al., Principles of Neurology, 6th ed, pp411-2)

Research Excerpts

ExcerptRelevanceReference
"In this study, efficacy of cyproheptadine for prevention of postoperative delirium was evaluated."9.22Cyproheptadine for the Prevention of Postoperative Delirium: A Pilot Study. ( Ahmadi, M; Arbabi, M; Cheraghchi, H; Khalili, H; Mohammadi, M, 2016)
"In this study, efficacy of cyproheptadine for prevention of postoperative delirium was evaluated."5.22Cyproheptadine for the Prevention of Postoperative Delirium: A Pilot Study. ( Ahmadi, M; Arbabi, M; Cheraghchi, H; Khalili, H; Mohammadi, M, 2016)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (33.33)29.6817
2010's2 (66.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Mohammadi, M1
Ahmadi, M1
Khalili, H1
Cheraghchi, H1
Arbabi, M1
Chu, FK1
Scott, J1
Pache, D1
Keane, G1
Buckle, H1
O'Brien, N1

Trials

1 trial available for cyproheptadine and Delirium

ArticleYear
Cyproheptadine for the Prevention of Postoperative Delirium: A Pilot Study.
    The Annals of pharmacotherapy, 2016, Volume: 50, Issue:3

    Topics: Adult; Aged; Cyproheptadine; Delirium; Double-Blind Method; Female; Histamine H1 Antagonists; Humans

2016

Other Studies

2 other studies available for cyproheptadine and Delirium

ArticleYear
Review of the epidemiology and characteristics of intentional cyproheptadine overdose in Hong Kong.
    Clinical toxicology (Philadelphia, Pa.), 2011, Volume: 49, Issue:7

    Topics: Adolescent; Adult; Age Distribution; Child; Cyproheptadine; Delirium; Dose-Response Relationship, Dr

2011
Prolonged anticholinergic delirium following antihistamine overdose.
    Australasian psychiatry : bulletin of Royal Australian and New Zealand College of Psychiatrists, 2007, Volume: 15, Issue:3

    Topics: Adolescent; Cholinergic Antagonists; Cyproheptadine; Cytochrome P-450 CYP2D6 Inhibitors; Delirium; D

2007