cyproheptadine has been researched along with Decerebrate Posturing in 8 studies
Cyproheptadine: A serotonin antagonist and a histamine H1 blocker used as antipruritic, appetite stimulant, antiallergic, and for the post-gastrectomy dumping syndrome, etc.
cyproheptadine : The product resulting from the formal oxidative coupling of position 5 of 5H-dibenzo[a,d]cycloheptene with position 4 of 1-methylpiperidine resulting in the formation of a double bond between the two fragments. It is a sedating antihistamine with antimuscarinic and calcium-channel blocking actions. It is used (particularly as the hydrochloride sesquihydrate) for the relief of allergic conditions including rhinitis, conjunctivitis due to inhalant allergens and foods, urticaria and angioedema, and in pruritic skin disorders. Unlike other antihistamines, it is also a seratonin receptor antagonist, making it useful in conditions such as vascular headache and anorexia.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In this study, we investigated the antinociceptive action of neurotropin in relation to the serotonergic system, a pain inhibitory system, and substance P, a pain transmitter; we also attempted to determine whether it acts at the spinal or supraspinal level in mice." | 3.67 | Analgesic mechanism of neurotropin: relation to the serotonergic system and influence of spinal cord transection. ( Hata, T; Itoh, E, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (75.00) | 18.7374 |
| 1990's | 1 (12.50) | 18.2507 |
| 2000's | 1 (12.50) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Honda, M | 1 |
| Nishida, T | 1 |
| Ono, H | 1 |
| el Tahir, KE | 1 |
| Ashour, MM | 1 |
| al-Harbi, MM | 1 |
| Bell, JA | 2 |
| Martin, WR | 2 |
| Sloan, JW | 1 |
| Buchwald, WF | 1 |
| Wang, RY | 1 |
| Aghajanian, GK | 1 |
| Maj, J | 1 |
| Palider, W | 1 |
| Baran, L | 1 |
| Sastry, BS | 1 |
| Sinclair, JG | 1 |
| Itoh, E | 1 |
| Hata, T | 1 |
8 other studies available for cyproheptadine and Decerebrate Posturing
| Article | Year |
|---|---|
Tricyclic analogs cyclobenzaprine, amitriptyline and cyproheptadine inhibit the spinal reflex transmission through 5-HT(2) receptors.
Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Cyproheptadine; Decerebrate State; Dose-Re | 2003 |
The cardiovascular actions of the volatile oil of the black seed (Nigella sativa) in rats: elucidation of the mechanism of action.
Topics: Animals; Atropine; Blood Pressure; Cyproheptadine; Decerebrate State; Heart Rate; Hemodynamics; Male | 1993 |
The effect of L-tryptophan on spinal cord C-fiber reflexes.
Topics: 5-Hydroxytryptophan; Action Potentials; Animals; Carboxy-Lyases; Cats; Cyproheptadine; Decerebrate S | 1976 |
Inhibiton of neurons in the amygdala by dorsal raphe stimulation: mediation through a direct serotonergic pathway.
Topics: 5-Hydroxytryptophan; Action Potentials; Amygdala; Animals; Brain Stem; Cyproheptadine; Decerebrate S | 1977 |
The effects of serotonergic and antiserotonergic drugs on the flexor reflex of spinal rat: a proposed model to evaluate the action on the central serotonin receptor.
Topics: 5-Hydroxytryptophan; Amphetamine; Animals; Anthracenes; Clonidine; Cyproheptadine; Decerebrate State | 1976 |
Serotonin involvement in the blockade of bulbospinal inhibition of the spinal monosynaptic reflex.
Topics: 5-Hydroxytryptophan; Animals; Blood Pressure; Cats; Cyproheptadine; Decerebrate State; Dose-Response | 1976 |
Analgesic mechanism of neurotropin: relation to the serotonergic system and influence of spinal cord transection.
Topics: Analgesics; Animals; Behavior, Animal; Cisterna Magna; Cyproheptadine; Decerebrate State; Fenclonine | 1989 |
Studies of tryptamine and lysergic acid diethylamide (LSD) on cutaneous C-fiber and polysynaptic reflexes in the cat.
Topics: Action Potentials; Analysis of Variance; Animals; Cats; Cyproheptadine; Decerebrate State; Drug Syne | 1974 |