cyproheptadine has been researched along with Cystic Fibrosis in 7 studies
Cyproheptadine: A serotonin antagonist and a histamine H1 blocker used as antipruritic, appetite stimulant, antiallergic, and for the post-gastrectomy dumping syndrome, etc.
cyproheptadine : The product resulting from the formal oxidative coupling of position 5 of 5H-dibenzo[a,d]cycloheptene with position 4 of 1-methylpiperidine resulting in the formation of a double bond between the two fragments. It is a sedating antihistamine with antimuscarinic and calcium-channel blocking actions. It is used (particularly as the hydrochloride sesquihydrate) for the relief of allergic conditions including rhinitis, conjunctivitis due to inhalant allergens and foods, urticaria and angioedema, and in pruritic skin disorders. Unlike other antihistamines, it is also a seratonin receptor antagonist, making it useful in conditions such as vascular headache and anorexia.
Cystic Fibrosis: An autosomal recessive genetic disease of the EXOCRINE GLANDS. It is caused by mutations in the gene encoding the CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR expressed in several organs including the LUNG, the PANCREAS, the BILIARY SYSTEM, and the SWEAT GLANDS. Cystic fibrosis is characterized by epithelial secretory dysfunction associated with ductal obstruction resulting in AIRWAY OBSTRUCTION; chronic RESPIRATORY INFECTIONS; PANCREATIC INSUFFICIENCY; maldigestion; salt depletion; and HEAT PROSTRATION.
| Excerpt | Relevance | Reference |
|---|---|---|
| " after treatment with CH were measured as well as dose-response relationship." | 5.62 | Cyproheptadine as an appetite stimulant in children with cystic fibrosis. ( Farrow, N; Grunert, J; La Vanda, C; Tai, A; van der Haak, N, 2021) |
| " after treatment with CH were measured as well as dose-response relationship." | 1.62 | Cyproheptadine as an appetite stimulant in children with cystic fibrosis. ( Farrow, N; Grunert, J; La Vanda, C; Tai, A; van der Haak, N, 2021) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (57.14) | 29.6817 |
| 2010's | 1 (14.29) | 24.3611 |
| 2020's | 2 (28.57) | 2.80 |
| Authors | Studies |
|---|---|
| McTavish, D | 1 |
| Thornton, J | 1 |
| Grunert, J | 1 |
| van der Haak, N | 1 |
| La Vanda, C | 1 |
| Farrow, N | 1 |
| Tai, A | 1 |
| Chinuck, R | 1 |
| Dewar, J | 1 |
| Baldwin, DR | 2 |
| Hendron, E | 1 |
| Homnick, DN | 3 |
| Homnick, BD | 1 |
| Reeves, AJ | 1 |
| Marks, JH | 3 |
| Pimentel, RS | 1 |
| Bonnema, SK | 2 |
| Hare, KL | 1 |
| Rubin, BK | 1 |
| Chinuck, RS | 1 |
| Fortnum, H | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effects of Cyproheptadine on Growth and Behavior in Pediatric Feeding Disorders[NCT02568007] | Phase 4 | 4 participants (Actual) | Interventional | 2015-12-31 | Terminated (stopped due to Unable to enroll adequate participants) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 reviews available for cyproheptadine and Cystic Fibrosis
| Article | Year |
|---|---|
Appetite stimulants for people with cystic fibrosis.
Topics: Adult; Anorexia; Anti-Bacterial Agents; Appetite Stimulants; Child; Cyproheptadine; Cystic Fibrosis; | 2022 |
Appetite stimulants for people with cystic fibrosis.
Topics: Anorexia; Appetite; Appetite Stimulants; Body Mass Index; Cyproheptadine; Cystic Fibrosis; Humans; M | 2014 |
Appetite stimulants in cystic fibrosis: a systematic review.
Topics: Anorexia; Appetite Stimulants; Body Weight; Cyproheptadine; Cystic Fibrosis; Dronabinol; Gastrointes | 2007 |
3 trials available for cyproheptadine and Cystic Fibrosis
| Article | Year |
|---|---|
Cyproheptadine is an effective appetite stimulant in cystic fibrosis.
Topics: Adolescent; Adult; Anthropometry; Appetite Stimulants; Body Mass Index; Body Weight; Case-Control St | 2004 |
Long-term trial of cyproheptadine as an appetite stimulant in cystic fibrosis.
Topics: Adolescent; Age Factors; Appetite Stimulants; Body Composition; Body Weight; Cyproheptadine; Cystic | 2005 |
The effect of a first-generation antihistamine on sputum viscoelasticity in cystic fibrosis.
Topics: Adolescent; Adult; Appetite Stimulants; Child; Cough; Cyproheptadine; Cystic Fibrosis; Double-Blind | 2007 |
1 other study available for cyproheptadine and Cystic Fibrosis
| Article | Year |
|---|---|
Cyproheptadine as an appetite stimulant in children with cystic fibrosis.
Topics: Appetite Stimulants; Body Mass Index; Child; Cyproheptadine; Cystic Fibrosis; Humans; Retrospective | 2021 |