cyproheptadine has been researched along with Cushing Syndrome in 82 studies
Cyproheptadine: A serotonin antagonist and a histamine H1 blocker used as antipruritic, appetite stimulant, antiallergic, and for the post-gastrectomy dumping syndrome, etc.
cyproheptadine : The product resulting from the formal oxidative coupling of position 5 of 5H-dibenzo[a,d]cycloheptene with position 4 of 1-methylpiperidine resulting in the formation of a double bond between the two fragments. It is a sedating antihistamine with antimuscarinic and calcium-channel blocking actions. It is used (particularly as the hydrochloride sesquihydrate) for the relief of allergic conditions including rhinitis, conjunctivitis due to inhalant allergens and foods, urticaria and angioedema, and in pruritic skin disorders. Unlike other antihistamines, it is also a seratonin receptor antagonist, making it useful in conditions such as vascular headache and anorexia.
Cushing Syndrome: A condition caused by prolonged exposure to excess levels of cortisol (HYDROCORTISONE) or other GLUCOCORTICOIDS from endogenous or exogenous sources. It is characterized by upper body OBESITY; OSTEOPOROSIS; HYPERTENSION; DIABETES MELLITUS; HIRSUTISM; AMENORRHEA; and excess body fluid. Endogenous Cushing syndrome or spontaneous hypercortisolism is divided into two groups, those due to an excess of ADRENOCORTICOTROPIN and those that are ACTH-independent.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A 44-year-old female with Cushing's disease associated with a pituitary macroadenoma was treated with cyproheptadine, 24 mg per day, after partial surgical resection of the tumor." | 7.67 | Rebound elevation of cortisol following cyproheptadine withdrawal in Cushing's disease from a pituitary macroadenoma. ( Ooi, TC; Twum-Barima, Y, 1987) |
| "In an attempt to delineate the mechanism and the site of action of cyproheptadine and dopaminergic agonists as well as hormones including thyrotropin-releasing hormone (TRH) and hydrocortisone, the effects of these substances on ACTH secretion from corticotroph adenoma cells in culture were examined." | 7.66 | Direct effects of thyrotropin-releasing hormone, cyproheptadine, and dopamine on adrenocorticotropin secretion from human corticotroph adenoma cells in vitro. ( Ishibashi, M; Yamaji, T, 1981) |
| "A young woman with Cushing's syndrome who had had amenorrhoea for six years was treated with cyproheptadine and became pregnant five months later." | 7.66 | Two pregnancies in a woman with Cushing's syndrome treated with cyproheptadine. Case report. ( Hartwig, W; Kasperlik-Załuska, A; Lozińska, D; Marianowski, L; Migdalska, B; Stopińska-Głuszak, U; Wilczyńska, J, 1980) |
| " Despite an increase in bromocriptine dosage to 30 mg daily and 24 mg/day cyproheptadine, the clinical and biochemical remission was not sustained in patient 1, and no further improvement occurred in patient 2." | 5.28 | Bromocriptine-responsive Cushing's disease associated with anterior pituitary corticotroph hyperplasia or normal pituitary gland. ( Croughs, RJ; Koppeschaar, HP; McNicol, AM; van't Verlaat, JW, 1989) |
| "A 44-year-old female with Cushing's disease associated with a pituitary macroadenoma was treated with cyproheptadine, 24 mg per day, after partial surgical resection of the tumor." | 3.67 | Rebound elevation of cortisol following cyproheptadine withdrawal in Cushing's disease from a pituitary macroadenoma. ( Ooi, TC; Twum-Barima, Y, 1987) |
| "In an attempt to delineate the mechanism and the site of action of cyproheptadine and dopaminergic agonists as well as hormones including thyrotropin-releasing hormone (TRH) and hydrocortisone, the effects of these substances on ACTH secretion from corticotroph adenoma cells in culture were examined." | 3.66 | Direct effects of thyrotropin-releasing hormone, cyproheptadine, and dopamine on adrenocorticotropin secretion from human corticotroph adenoma cells in vitro. ( Ishibashi, M; Yamaji, T, 1981) |
| "Direct effects of cyproheptadine, reserpine, synthetic ovine corticotropin-releasing factor (CRF), dexamethasone, and lysine-8-vasopressin (LVP) on the secretion of immunoreactive ACTH and beta-endorphin from the adenoma and the nonadenomatous tissue of patients with Cushing's disease were examined using a superfusion system." | 3.66 | Effects of cyproheptadine, reserpine, and synthetic corticotropin-releasing factor on pituitary glands from patients with Cushing's disease. ( Demura, H; Mouri, T; Sasaki, A; Shibasaki, T; Shizume, K; Suda, T; Tozawa, F, 1983) |
| "A young woman with Cushing's syndrome who had had amenorrhoea for six years was treated with cyproheptadine and became pregnant five months later." | 3.66 | Two pregnancies in a woman with Cushing's syndrome treated with cyproheptadine. Case report. ( Hartwig, W; Kasperlik-Załuska, A; Lozińska, D; Marianowski, L; Migdalska, B; Stopińska-Głuszak, U; Wilczyńska, J, 1980) |
| "Treatment with metyrapone or o,p'-DDD can always induce a clinical remission but not a cure, and neurotransmitter therapy may be effective in a minority of cases." | 2.37 | Cushing's syndrome. ( Besser, GM; Howlett, TA; Rees, LH, 1985) |
| " Remission was achieved with cyproheptadine up to a dosage of 24 mg/day." | 1.29 | Cyproheptadine treatment in Cushing's disease. ( Alagöl, F; Azizlerli, H; Berker, F; Sandalci, O; Tanakol, R; Terzioğlu, T, 1996) |
| " Despite an increase in bromocriptine dosage to 30 mg daily and 24 mg/day cyproheptadine, the clinical and biochemical remission was not sustained in patient 1, and no further improvement occurred in patient 2." | 1.28 | Bromocriptine-responsive Cushing's disease associated with anterior pituitary corticotroph hyperplasia or normal pituitary gland. ( Croughs, RJ; Koppeschaar, HP; McNicol, AM; van't Verlaat, JW, 1989) |
| "Cyproheptadine has been reported to effect remissions in up to 50% of patients with Cushing's disease presumably at a hypothalamic level." | 1.28 | Cyproheptadine may act at the pituitary in Cushing's disease: evidence from CRF stimulation. ( Jackson, IM; Nowakowski, KJ; Tucci, JR, 1989) |
| "Treatment with cyproheptadine again induced hypocorticism necessitating corticosteroid substitution therapy." | 1.27 | Sodium valproate and cyproheptadine may independently induce a remission in the same patient with Cushing's disease. ( Croughs, RJ; Koppeschaar, HP; Schwarz, F; Thijssen, JH, 1983) |
| " Long-term administration of cyproheptadine appeared to normalize excessive adrenocorticotropic hormone (ACTH) production by reducing the frequency and the peak levels of episodic secretion of ACTH." | 1.26 | Cyproheptadine in the control of Cushing's disease. ( Gann, DS; Hsu, TH; Russell, RP; Tsan, KW, 1981) |
| "Ectopic secretion of GH by the carcinoid hepatic metastases was documented by both RIA and immunohistochemical techniques." | 1.26 | Acromegaly and Cushing's syndrome associated with a foregut carcinoid tumor. ( Buckley, PJ; Daughaday, WH; Deschryver, K; Greider, MH; Jaffe, BM; Leveston, SA; McKeel, DW, 1981) |
| "Cyproheptadine is a potent antagonist of serotonin and has been used successfully in some patients with Cushing's disease, although, generally, in women without radiological evidence of pituitary tumors." | 1.26 | Cyproheptadine-induced remission of Cushing's disease due to pituitary basophil adenoma. ( Bellido, C; Jaimez, L; Jimenez-Alonso, J; Jiménez-Perepérez, JA; Munoz-Avila, J; Pérez-Jimenez, F, 1982) |
| "Cyproheptadine treatment resulted in a marked lowering of plasma ACTH concentrations (221-320 pg/ml)." | 1.26 | Cortisol and androgen secretion in a case of Nelson's syndrome with paratesticular tumors: response to cyproheptadine therapy. ( Bardin, CW; Krieger, DT; Samojlik, E, 1978) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 70 (85.37) | 18.7374 |
| 1990's | 10 (12.20) | 18.2507 |
| 2000's | 2 (2.44) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Perkins, GA | 1 |
| Lamb, S | 1 |
| Erb, HN | 1 |
| Schanbacher, B | 1 |
| Nydam, DV | 1 |
| Divers, TJ | 1 |
| Garcia, C | 1 |
| Bordier, L | 1 |
| Garcia-Hejl, C | 1 |
| Ceppa, F | 1 |
| Mayaudon, H | 1 |
| Dupuy, O | 1 |
| Bauduceau, B | 1 |
| Slavnov, VN | 5 |
| Valueva, GV | 3 |
| Luchitskiĭ, EV | 4 |
| Krieger, DT | 7 |
| Calderón Gualda, MD | 1 |
| Martínez de Osaba, MJ | 1 |
| Palacín, A | 1 |
| Vilardell, E | 1 |
| Aronin, N | 1 |
| Hsu, TH | 1 |
| Gann, DS | 1 |
| Tsan, KW | 1 |
| Russell, RP | 1 |
| Leveston, SA | 1 |
| McKeel, DW | 1 |
| Buckley, PJ | 1 |
| Deschryver, K | 1 |
| Greider, MH | 1 |
| Jaffe, BM | 1 |
| Daughaday, WH | 1 |
| Ishibashi, M | 1 |
| Yamaji, T | 1 |
| Lankford, HV | 1 |
| Tucker, HS | 1 |
| Blackard, WG | 1 |
| Weiss, MH | 1 |
| Komissarenko, IV | 1 |
| Cheban, AK | 2 |
| Rybakov, SI | 1 |
| Pomerantsev, IuV | 1 |
| Slavnov, VI | 1 |
| Richkind, M | 1 |
| Jordan, RM | 1 |
| Ramos-Gabatin, A | 1 |
| Kendall, JW | 1 |
| Gaudette, D | 1 |
| Walls, RC | 1 |
| Bergstrand, CG | 1 |
| Nilsson, KO | 1 |
| Jimenez-Alonso, J | 1 |
| Munoz-Avila, J | 1 |
| Jaimez, L | 1 |
| Pérez-Jimenez, F | 1 |
| Bellido, C | 1 |
| Jiménez-Perepérez, JA | 1 |
| Suda, T | 1 |
| Tozawa, F | 1 |
| Mouri, T | 1 |
| Sasaki, A | 1 |
| Shibasaki, T | 1 |
| Demura, H | 1 |
| Shizume, K | 1 |
| Koppeschaar, HP | 4 |
| Croughs, RJ | 4 |
| Thijssen, JH | 2 |
| Schwarz, F | 2 |
| Couch, RM | 1 |
| Smail, PJ | 1 |
| Dean, HJ | 1 |
| Winter, JS | 1 |
| Stolp, R | 1 |
| Rijnberk, A | 1 |
| Wiesen, M | 1 |
| Ross, F | 1 |
| Khir, AS | 1 |
| How, J | 1 |
| Bewsher, PD | 1 |
| Bricaire, H | 2 |
| Luton, JP | 2 |
| Griffith, DN | 1 |
| Rose, EJ | 1 |
| Terayama, Y | 1 |
| Furusawa, M | 1 |
| Hitomi, H | 1 |
| Morita, S | 1 |
| Futagawara, K | 1 |
| Jialal, I | 1 |
| Pillay, NL | 1 |
| Kasperlik-Załuska, A | 2 |
| Migdalska, B | 2 |
| Hartwig, W | 1 |
| Wilczyńska, J | 1 |
| Marianowski, L | 1 |
| Stopińska-Głuszak, U | 1 |
| Lozińska, D | 1 |
| Miller, JW | 1 |
| Crapo, L | 1 |
| Miura, K | 1 |
| Prattichizzo, FA | 1 |
| Peterson, ME | 1 |
| Kintzer, PP | 1 |
| van Waveren Hogervorst, CO | 1 |
| Zelissen, PM | 1 |
| Lips, CJ | 1 |
| Garcia, BM | 1 |
| Tanakol, R | 1 |
| Alagöl, F | 1 |
| Azizlerli, H | 1 |
| Sandalci, O | 1 |
| Terzioğlu, T | 1 |
| Berker, F | 1 |
| Barnes, P | 1 |
| Shaw, K | 1 |
| Ross, E | 1 |
| Pearce, CJ | 1 |
| Isaacs, AJ | 1 |
| Gomez, J | 1 |
| Marek, J | 2 |
| Matys, Z | 2 |
| Gregorová, I | 2 |
| Feldman, JM | 2 |
| Esposito, V | 1 |
| D'Alessandro, B | 1 |
| Bellastella, A | 1 |
| Iacono, G | 1 |
| Bizzarro, A | 1 |
| Officioso, A | 1 |
| Piccolo, C | 1 |
| Ghnassia, JP | 1 |
| McPherson, HT | 1 |
| Jannì, A | 1 |
| Carmina, E | 1 |
| Lanzara, P | 1 |
| Lo Coco, R | 1 |
| Longo, RA | 1 |
| Ambrosi, B | 1 |
| Gaggini, M | 1 |
| Secchi, F | 1 |
| Faglia, G | 1 |
| Samojlik, E | 1 |
| Bardin, CW | 1 |
| Price, J | 1 |
| Ward, G | 1 |
| Michelsen, H | 1 |
| Contreras, P | 1 |
| Bradford, I | 1 |
| Rojas, A | 1 |
| Prinz, RA | 2 |
| Brooks, MH | 2 |
| Lawrence, AM | 2 |
| Paloyan, E | 2 |
| Grant, DB | 1 |
| Atherden, SM | 1 |
| Seyer-Hansen, K | 1 |
| Weeke, J | 1 |
| Møller, J | 1 |
| González, LR | 1 |
| Gándara, JR | 1 |
| Scott, R | 1 |
| Espiner, EA | 1 |
| Donald, RA | 1 |
| Allgrove, J | 1 |
| Husband, P | 1 |
| Brook, CG | 1 |
| D'Ercole, AJ | 1 |
| Morris, MA | 1 |
| Underwood, LE | 1 |
| Van Wyk, JJ | 1 |
| Burrows, AW | 1 |
| Burke, CW | 1 |
| Rees, LH | 2 |
| Tyrrell, JB | 1 |
| Brooks, RM | 1 |
| Forsham, PH | 1 |
| George, WF | 1 |
| Husain, M | 1 |
| Lock, JP | 1 |
| Katz, FH | 1 |
| Vetter, W | 1 |
| Vetter, H | 1 |
| Beckerhoff, R | 1 |
| Würsten, D | 1 |
| Siegenthaler, W | 1 |
| Amorosa, L | 1 |
| Linick, F | 1 |
| Kato, Y | 1 |
| García Rojas, JF | 1 |
| Mangas Rojas, A | 1 |
| Barba Chacón, A | 1 |
| García Osle, M | 1 |
| Zamora Madaria, E | 1 |
| Whitehead, HM | 1 |
| Beacom, R | 1 |
| Sheridan, B | 2 |
| Atkinson, AB | 2 |
| van't Verlaat, JW | 1 |
| McNicol, AM | 1 |
| Tucci, JR | 1 |
| Nowakowski, KJ | 1 |
| Jackson, IM | 1 |
| Jeske, W | 1 |
| Wiśniewska-Woźniak, T | 1 |
| Sek, S | 1 |
| Luchitsky, EV | 1 |
| Kennedy, AL | 1 |
| Carson, DJ | 1 |
| Hadden, DR | 1 |
| Weaver, JA | 1 |
| Howlett, TA | 1 |
| Besser, GM | 1 |
| Yoshida, H | 1 |
| Takeda, F | 1 |
| Kinouchi, T | 1 |
| Shimizu, N | 1 |
| Ooi, TC | 1 |
| Twum-Barima, Y | 1 |
| Burch, WM | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| An Open-label Study of the Efficacy and Safety of CORLUX (Mifepristone) in the Treatment of the Signs and Symptoms of Endogenous Cushing's Syndrome[NCT00569582] | Phase 3 | 50 participants (Actual) | Interventional | 2007-12-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Responder is defined as subject with a decrease greater than or equal to 5mm Hg in diastolic blood pressure from baseline to week 24 or last visit. (NCT00569582)
Timeframe: Baseline to Week 24
| Intervention | participants (Number) |
|---|---|
| Mifepristone | 8 |
Responder is defined as subject with a decrease greater than or equal to 25% in area under the curve for glucose on 2-hour oral glucose test from baseline to week 24 or last visit, for Cushing's patients with type-2 diabetes mellitus/impaired glucose tolerance. (NCT00569582)
Timeframe: Baseline to Week 24
| Intervention | participants (Number) |
|---|---|
| Mifepristone | 15 |
10 reviews available for cyproheptadine and Cushing Syndrome
| Article | Year |
|---|---|
Physiopathology of Cushing's disease.
Topics: Adenoma; Biomechanical Phenomena; Bromocriptine; Circadian Rhythm; Cushing Syndrome; Cyproheptadine; | 1983 |
Treatment of Cushing's disease in children.
Topics: Adrenalectomy; Adrenocorticotropic Hormone; Aminoglutethimide; Bromocriptine; Child; Cushing Syndrom | 1982 |
The medical treatment of Cushing's syndrome.
Topics: Adrenal Cortex Neoplasms; Adrenal Glands; Aminoglutethimide; Animals; Bromocriptine; Cushing Syndrom | 1993 |
[Non-invasive therapy of Cushing's syndrome].
Topics: Aminoglutethimide; Betamethasone; Bromocriptine; Clinical Trials as Topic; Cushing Syndrome; Cyprohe | 1994 |
Medical treatment of pituitary-dependent hyperadrenocorticism in dogs.
Topics: Animals; Bromocriptine; Cushing Syndrome; Cyproheptadine; Dog Diseases; Dogs; Drug Administration Sc | 1994 |
Cushing's syndrome.
Topics: Adolescent; Adrenal Cortex Function Tests; Adrenal Cortex Neoplasms; Adrenal Gland Neoplasms; Adrena | 1977 |
[Drug therapy of pituitary tumors].
Topics: Bromocriptine; Cushing Syndrome; Cyproheptadine; Female; Humans; Male; Metyrapone; Octreotide; Pitui | 1991 |
Cushing's syndrome.
Topics: Adrenal Cortex Hormones; Adrenal Gland Neoplasms; Adrenalectomy; Adrenocorticotropic Hormone; Alcoho | 1985 |
[Drug and radiotherapy of pituitary tumors].
Topics: Acromegaly; Adenoma; Adrenocorticotropic Hormone; Bromocriptine; Cushing Syndrome; Cyproheptadine; G | 1986 |
Cushing's disease. A review.
Topics: Adenoma; Adolescent; Adrenalectomy; Adult; Animals; Bromocriptine; Child; Combined Modality Therapy; | 1985 |
4 trials available for cyproheptadine and Cushing Syndrome
| Article | Year |
|---|---|
[Use of cyproheptadine in the treatment of Cushing's disease].
Topics: Adrenocorticotropic Hormone; Adult; Clinical Trials as Topic; Cushing Syndrome; Cyproheptadine; Drug | 1979 |
[Treatment of cushing's disease with cypropheptadine (author's transl)].
Topics: Adult; Circadian Rhythm; Clinical Trials as Topic; Cushing Syndrome; Cyproheptadine; Drug Evaluation | 1977 |
[Treatment with cyproheptadine of a recurrent case of Cushing's disease].
Topics: Adult; Clinical Trials as Topic; Cushing Syndrome; Cyproheptadine; Drug Evaluation; Female; Humans; | 1976 |
[Criteria for the selection of drugs for the pathogenetic treatment of Itsenko-Cushing disease].
Topics: Adrenocorticotropic Hormone; Adult; Bromocriptine; Clinical Trials as Topic; Cushing Syndrome; Cypro | 1985 |
68 other studies available for cyproheptadine and Cushing Syndrome
| Article | Year |
|---|---|
Plasma adrenocorticotropin (ACTH) concentrations and clinical response in horses treated for equine Cushing's disease with cyproheptadine or pergolide.
Topics: Adrenocorticotropic Hormone; Animals; Cushing Syndrome; Cyproheptadine; Drug Monitoring; Female; Hor | 2002 |
[Nelson's syndrome management: current knowledge].
Topics: Adolescent; Adrenalectomy; Adrenocorticotropic Hormone; Cushing Syndrome; Cyproheptadine; Diagnosis, | 2007 |
[Dynamics of beta-lipotropin and beta-endorphin levels in Itsenko-Cushing disease patients being treated with the antiserotonin preparation cyproheptadine (peritol) and chloditan].
Topics: Adolescent; Adrenocorticotropic Hormone; Adult; beta-Endorphin; beta-Lipotropin; Cushing Syndrome; C | 1984 |
[An ACTH-secreting pituitary macroadenoma: inhibitory effect of cyproheptadine and somatostatin].
Topics: Adenoma; Cushing Syndrome; Cyproheptadine; Female; Humans; Middle Aged; Pituitary Neoplasms; Somatos | 1984 |
Sustained remission of Nelson's syndrome after stopping cyproheptadine treatment.
Topics: Adrenalectomy; Adrenocorticotropic Hormone; Adult; Circadian Rhythm; Cushing Syndrome; Cyproheptadin | 1980 |
Cyproheptadine in the control of Cushing's disease.
Topics: Adrenocorticotropic Hormone; Adult; Cushing Syndrome; Cyproheptadine; Female; Humans; Hydrocortisone | 1981 |
Acromegaly and Cushing's syndrome associated with a foregut carcinoid tumor.
Topics: Abdominal Neoplasms; Acromegaly; Adolescent; Adrenocorticotropic Hormone; Carcinoid Tumor; Cushing S | 1981 |
Direct effects of thyrotropin-releasing hormone, cyproheptadine, and dopamine on adrenocorticotropin secretion from human corticotroph adenoma cells in vitro.
Topics: Adenoma; Adrenocorticotropic Hormone; Cells, Cultured; Cushing Syndrome; Cyproheptadine; Dopamine; H | 1981 |
A cyproheptadine-reversible defect in ACTH control persisting after removal of the pituitary tumor in Cushing's disease.
Topics: Adenoma; Adrenalectomy; Adrenocorticotropic Hormone; Cushing Syndrome; Cyproheptadine; Feedback; Hum | 1981 |
Medical and surgical management of functional pituitary tumors.
Topics: Acromegaly; Adrenocorticotropic Hormone; Bromocriptine; Cushing Syndrome; Cyproheptadine; Growth Hor | 1981 |
[Use of cyproheptadine (Peritol) as a drug blocking corticotropin secretion in the treatment of Cushing's syndrome].
Topics: Adrenocorticotropic Hormone; Cushing Syndrome; Cyproheptadine; Depression, Chemical; Drug Therapy, C | 1981 |
Defect in ACTH control after hypophysectomy in Cushing's disease.
Topics: Adrenocorticotropic Hormone; Animals; Cushing Syndrome; Cyproheptadine; Feedback; Humans; Hydrocorti | 1982 |
Cushing syndrome in dogs: treatment with bromocriptine and cyproheptadine.
Topics: Adrenocorticotropic Hormone; Animals; Bromocriptine; Cushing Syndrome; Cyproheptadine; Dog Diseases; | 1981 |
Dynamics of adrenocorticotropin (ACTH) secretion in cyclic Cushing's syndrome: evidence for more than one abnormal ACTH biorhythm.
Topics: Adrenalectomy; Adrenocorticotropic Hormone; Circadian Rhythm; Cushing Syndrome; Cyproheptadine; Fema | 1982 |
Cyproheptadine-induced remission of Cushing's disease due to pituitary basophil adenoma.
Topics: Adenoma, Basophil; Adrenocorticotropic Hormone; Cushing Syndrome; Cyproheptadine; Humans; Male; Midd | 1982 |
Effects of cyproheptadine, reserpine, and synthetic corticotropin-releasing factor on pituitary glands from patients with Cushing's disease.
Topics: Adenoma; Adrenocorticotropic Hormone; beta-Endorphin; Corticotropin-Releasing Hormone; Cushing Syndr | 1983 |
Sodium valproate and cyproheptadine may independently induce a remission in the same patient with Cushing's disease.
Topics: Adrenocorticotropic Hormone; Adult; Bromocriptine; Cushing Syndrome; Cyproheptadine; Dexamethasone; | 1983 |
Prolonged remission of Cushing disease after treatment with cyproheptadine.
Topics: Adrenocorticotropic Hormone; Child; Cushing Syndrome; Cyproheptadine; Depression, Chemical; Humans; | 1984 |
[Function of the hypophysis in patients with Itsenko-Cushing disease treated with peritol and chloditan].
Topics: Adolescent; Adult; Cushing Syndrome; Cyproheptadine; Female; Humans; Male; Middle Aged; Mitotane; Pi | 1983 |
Results of cyproheptadine treatment in dogs with pituitary-dependent hyperadrenocorticism.
Topics: Adrenal Cortex Hormones; Animals; Cushing Syndrome; Cyproheptadine; Dog Diseases; Dogs; Female; Hydr | 1984 |
Prolonged remission of a case of Cushing's disease following cessation of cyproheptadine therapy.
Topics: Adult; Cushing Syndrome; Cyproheptadine; Female; Humans | 1983 |
Successful pregnancy after cyproheptadine treatment for Cushing's disease.
Topics: Adult; Cushing Syndrome; Cyproheptadine; Female; Humans; Pregnancy; Pregnancy Complications | 1982 |
[Cushing's syndrome. Medical treatment of adrenal hypercorticism].
Topics: Adrenal Gland Neoplasms; Aminoglutethimide; Androstanols; Bromocriptine; Cushing Syndrome; Cyprohept | 1980 |
Pregnancy after cyproheptadine treatment for Cushing's disease.
Topics: Adult; Cushing Syndrome; Cyproheptadine; Female; Humans; Infant, Newborn; Male; Pregnancy; Remission | 1981 |
[Treatment of Cushing's disease with cyproheptadine (author's transl)].
Topics: Adolescent; Adult; Cushing Syndrome; Cyproheptadine; Female; Humans; Male; Middle Aged | 1981 |
Cyproheptadine therapy in Cushing's disease and Nelson's syndrome.
Topics: Adult; Blood Pressure; Body Weight; Cushing Syndrome; Cyproheptadine; Female; Humans; Nelson Syndrom | 1980 |
Two pregnancies in a woman with Cushing's syndrome treated with cyproheptadine. Case report.
Topics: Adult; Cushing Syndrome; Cyproheptadine; Female; Hormones; Humans; Pregnancy; Pregnancy Complication | 1980 |
[Arterial hypertension in Cushing's disease: the 24-hour pressure profile without and during treatment with beta-blockers or cyproheptadine].
Topics: Adrenergic beta-Antagonists; Blood Pressure; Blood Pressure Monitors; Circadian Rhythm; Cushing Synd | 1994 |
Cortisol secretory patterns in Cushing's disease and response to cyproheptadine treatment.
Topics: Adenoma; Adult; Cushing Syndrome; Cyproheptadine; Female; Humans; Hydrocortisone; Male; Middle Aged; | 1996 |
Cyproheptadine treatment in Cushing's disease.
Topics: Adenoma; Adolescent; Cushing Syndrome; Cyproheptadine; Female; Follow-Up Studies; Humans; Pituitary | 1996 |
Editorial: New drug treatment for Cushing's disease.
Topics: Cushing Syndrome; Cyproheptadine; Drug Evaluation; Humans | 1975 |
Cushing's disease: Successful treatment with cyproheptadine.
Topics: Adolescent; Adrenal Cortex Function Tests; Cushing Syndrome; Cyproheptadine; Drug Evaluation; Female | 1977 |
Treatment of Cushing's disease with cyproheptadine.
Topics: Adult; Bipolar Disorder; Cushing Syndrome; Cyproheptadine; Drug Evaluation; Female; Humans; Psychose | 1977 |
Cyproheptadine in Cushing's syndrome.
Topics: 17-Hydroxycorticosteroids; Adrenal Cortex Function Tests; Adult; Bromocriptine; Cushing Syndrome; Cy | 1977 |
Cyproheptadine.
Topics: Appetite; Body Weight; Cushing Syndrome; Cyproheptadine; Drug Evaluation; Humans | 1978 |
Editorial: Cushing's disease: a hypothalamic flush?
Topics: Adrenocorticotropic Hormone; Cushing Syndrome; Cyproheptadine; Humans; Hypothalamus; Serotonin | 1975 |
More on cyproheptadine in Cushing's disease.
Topics: Adrenocorticotropic Hormone; Cushing Syndrome; Cyproheptadine; Depression, Chemical; Female; Humans; | 1977 |
[Effect of cyproheptadine on plasma ACTH and cortisol secretion in a patient with Cushing's disease].
Topics: 17-Hydroxycorticosteroids; Adrenal Cortex Function Tests; Adrenocorticotropic Hormone; Adult; Cushin | 1976 |
[Medical treatment and Cushing's disease].
Topics: Aminoglutethimide; Bromocriptine; Cushing Syndrome; Cyproheptadine; Humans; Mitotane | 1977 |
The central nervous system and Cushing's disease.
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Adrenocorticotropic Hormone; Central Nervous Syste | 1978 |
Serotonin regulation of ACTH secretion.
Topics: Adrenocorticotropic Hormone; Animals; Brain Chemistry; Cats; Cushing Syndrome; Cyproheptadine; Guine | 1977 |
Lack of effect of antiserotoninergic and/or dopaminergic treatment in patients with pituitary-dependent Cushing's syndrome.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenocorticotropic Hormone; Cushing Syndrome; Cyprohept | 1979 |
Cortisol and androgen secretion in a case of Nelson's syndrome with paratesticular tumors: response to cyproheptadine therapy.
Topics: Adrenalectomy; Adrenocorticotropic Hormone; Adult; Androgens; Cushing Syndrome; Cyproheptadine; Huma | 1978 |
Cyproheptadine in bipolar affective illness with cushingoid features.
Topics: Adult; Bipolar Disorder; Cushing Syndrome; Cyproheptadine; Female; Humans | 1977 |
The continued importance of adrenalectomy in the treatment of Cushing's disease.
Topics: Adolescent; Adrenalectomy; Adult; Cushing Syndrome; Cyproheptadine; Female; Humans; Hypophysectomy; | 1979 |
Cushing's disease: the role of adrenalectomy and autotransplantation.
Topics: Adolescent; Adosterol; Adrenal Glands; Adrenalectomy; Cushing Syndrome; Cyproheptadine; Female; Huma | 1979 |
Cushing's disease presenting with growth failure: clinical remission during cyproheptadine therapy.
Topics: Adolescent; Cushing Syndrome; Cyproheptadine; Follow-Up Studies; Growth Disorders; Humans; Hydrocort | 1979 |
[Drug treatment of Cushing's syndrome with cyproheptadine].
Topics: Adult; Cushing Syndrome; Cyproheptadine; Drug Evaluation; Female; Humans; Middle Aged | 1979 |
Cyproheptadine for Cushing's disease (cont.)
Topics: Adult; Cushing Syndrome; Cyproheptadine; Female; Humans | 1977 |
Cushing's disease: failure of treatment with cyproheptadine.
Topics: Adolescent; Cushing Syndrome; Cyproheptadine; Humans; Male | 1977 |
Treatment of Cushing disease in Childhood with cyproheptadine.
Topics: Adolescent; Child; Cushing Syndrome; Cyproheptadine; Female; Humans; Male | 1977 |
Cyproheptadine and Cushing's disease.
Topics: Adolescent; Cushing Syndrome; Cyproheptadine; Female; Humans; Male; Middle Aged | 1977 |
[Cyproheptadin in the treatment of Cushing's syndrome (author's transl)].
Topics: Adult; Cushing Syndrome; Cyproheptadine; Female; Humans; Male | 1977 |
Letter: Cyproheptadine for pituitary disorders.
Topics: Adult; Cushing Syndrome; Cyproheptadine; Female; Humans; Pituitary Diseases | 1976 |
More on cyproheptadine.
Topics: Cushing Syndrome; Cyproheptadine; Drug Evaluation; Female; Humans; Male | 1976 |
Failure of cyprohepatdine to inhibit vasopressin-stimulated cortisol release in a patient with Cushing's disease.
Topics: Adult; Cushing Syndrome; Cyproheptadine; Female; Humans; Hydrocortisone; Insulin; Pituitary Gland; T | 1976 |
[Transitory remission of hypercorticism by means of cyproheptadine in a patient with Cushing syndrome].
Topics: Adrenalectomy; Adrenocortical Hyperfunction; Cushing Syndrome; Cyproheptadine; Humans; Hydrocortison | 1976 |
Cyproheptadine-induced remission of Cushing's disease.
Topics: Adrenal Cortex Hormones; Adult; Cushing Syndrome; Cyproheptadine; Female; Humans; Pituitary-Adrenal | 1975 |
[Clinical remission in Cushing's disease through treatment with sodium valproate and bromocriptine].
Topics: Bromocriptine; Chronic Disease; Cushing Syndrome; Cyproheptadine; Drug Therapy, Combination; Female; | 1991 |
The effect of cyproheptadine and/or bromocriptine on plasma ACTH levels in patients cured of Cushing's disease by bilateral adrenalectomy.
Topics: Adrenalectomy; Adrenocorticotropic Hormone; Adult; Aged; Bromocriptine; Cushing Syndrome; Cyprohepta | 1990 |
[Changes in the secretion of the hormones of the hypothalamo-hypophyseo-adrenal system in Itsenko-Cushing disease under the influence of insulin-induced hypoglycemia and thyroliberin].
Topics: Adolescent; Adrenocorticotropic Hormone; Adult; Cushing Syndrome; Cyproheptadine; Fasting; Humans; H | 1990 |
Bromocriptine-responsive Cushing's disease associated with anterior pituitary corticotroph hyperplasia or normal pituitary gland.
Topics: Adolescent; Adrenocorticotropic Hormone; Bromocriptine; Cushing Syndrome; Cyproheptadine; Humans; Hy | 1989 |
Cyproheptadine may act at the pituitary in Cushing's disease: evidence from CRF stimulation.
Topics: 17-Hydroxycorticosteroids; Adrenocorticotropic Hormone; Adult; Corticotropin-Releasing Hormone; Cush | 1989 |
The relationship between cortisol and ACTH in patients with Cushing's disease following neurosurgery or pharmacotherapy.
Topics: Adolescent; Adrenocorticotropic Hormone; Adult; Aminoglutethimide; Cushing Syndrome; Cyproheptadine; | 1989 |
Effect of the antiserotonin drug, cyproheptadine, on plasma beta-endorphin and beta-lipotropin in patients with Itsenko-Cushing's disease.
Topics: Adolescent; Adrenocorticotropic Hormone; Adult; beta-Endorphin; beta-Lipotropin; Cushing Syndrome; C | 1985 |
Five cases of cyclical Cushing's syndrome.
Topics: Adrenocorticotropic Hormone; Adult; Aged; Bromocriptine; Child, Preschool; Creatinine; Cushing Syndr | 1985 |
Response to neurotransmitter modulating drugs in patients with Cushing's disease.
Topics: Adolescent; Adult; Bromocriptine; Cushing Syndrome; Cyproheptadine; Female; Humans; Hydrocortisone; | 1986 |
Rebound elevation of cortisol following cyproheptadine withdrawal in Cushing's disease from a pituitary macroadenoma.
Topics: Adenoma; Adult; Cushing Syndrome; Cyproheptadine; Female; Humans; Hydrocortisone; Pituitary Neoplasm | 1987 |