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cyproheptadine and Conjunctivitis, Allergic

cyproheptadine has been researched along with Conjunctivitis, Allergic in 7 studies

Cyproheptadine: A serotonin antagonist and a histamine H1 blocker used as antipruritic, appetite stimulant, antiallergic, and for the post-gastrectomy dumping syndrome, etc.
cyproheptadine : The product resulting from the formal oxidative coupling of position 5 of 5H-dibenzo[a,d]cycloheptene with position 4 of 1-methylpiperidine resulting in the formation of a double bond between the two fragments. It is a sedating antihistamine with antimuscarinic and calcium-channel blocking actions. It is used (particularly as the hydrochloride sesquihydrate) for the relief of allergic conditions including rhinitis, conjunctivitis due to inhalant allergens and foods, urticaria and angioedema, and in pruritic skin disorders. Unlike other antihistamines, it is also a seratonin receptor antagonist, making it useful in conditions such as vascular headache and anorexia.

Conjunctivitis, Allergic: Conjunctivitis due to hypersensitivity to various allergens.

Research Excerpts

ExcerptRelevanceReference
" Rupatadine, a molecule with intense antihistaminic activity and with antagonist PAF effects through its interaction with specific receptors, is indicated for the treatment of intermittent or persistent allergic rhinitis and urticaria."4.89Efficacy and safety of rupatadine for allergic rhino-conjunctivitis: a systematic review of randomized, double-blind, placebo-controlled studies with meta-analysis. ( Canonica, GW; Compalati, E, 2013)
"Rupatadine is a better choice for seasonal allergic rhinitis compared with levocetirizine because of its better efficacy and safety profile."2.75Rupatadine and levocetirizine for seasonal allergic rhinitis: a comparative study of efficacy and safety. ( Allala, U; Jaida, J; Maiti, R; Palani, A; Rahman, J, 2010)
"Pretreatment with Loratadine resulted in a significant higher allergen threshold dose than placebo (p less than 0."2.67Protective effect of loratadine on specific conjunctival provocation test. ( Buscaglia, S; Canonica, GW; Ciprandi, G; Marchesi, E; Pesce, GP, 1991)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (28.57)18.2507
2000's0 (0.00)29.6817
2010's5 (71.43)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Simpson, RS1
Lee, JK1
Compalati, E2
Canonica, GW3
Berger, VW1
Gudehithlu, SK1
Maiti, R1
Rahman, J1
Jaida, J1
Allala, U1
Palani, A1
Boner, AL1
Richelli, C1
Castellani, C1
Marchesi, E2
Andreoli, A1
Ciprandi, G1
Buscaglia, S1
Pesce, GP1

Reviews

1 review available for cyproheptadine and Conjunctivitis, Allergic

ArticleYear
Efficacy and safety of rupatadine for allergic rhino-conjunctivitis: a systematic review of randomized, double-blind, placebo-controlled studies with meta-analysis.
    Current medical research and opinion, 2013, Volume: 29, Issue:11

    Topics: Conjunctivitis, Allergic; Cyproheptadine; Histamine Antagonists; Humans; Platelet Activating Factor;

2013

Trials

3 trials available for cyproheptadine and Conjunctivitis, Allergic

ArticleYear
Rupatadine and levocetirizine for seasonal allergic rhinitis: a comparative study of efficacy and safety.
    Archives of otolaryngology--head & neck surgery, 2010, Volume: 136, Issue:8

    Topics: Adolescent; Adult; Cetirizine; Conjunctivitis, Allergic; Cyproheptadine; Eosinophils; Female; Histam

2010
Comparison of the effects of loratadine and astemizole in the treatment of children with seasonal allergic rhinoconjunctivitis.
    Allergy, 1992, Volume: 47, Issue:2 Pt 1

    Topics: Adolescent; Astemizole; Child; Conjunctivitis, Allergic; Cyproheptadine; Female; Histamine Antagonis

1992
Protective effect of loratadine on specific conjunctival provocation test.
    International archives of allergy and applied immunology, 1991, Volume: 96, Issue:4

    Topics: Adolescent; Adult; Aged; Conjunctiva; Conjunctivitis, Allergic; Cyproheptadine; Double-Blind Method;

1991

Other Studies

3 other studies available for cyproheptadine and Conjunctivitis, Allergic

ArticleYear
Omalizumab as single-dose therapy for vernal keratoconjunctivitis.
    Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2019, Volume: 122, Issue:1

    Topics: Anti-Allergic Agents; Conjunctivitis, Allergic; Cyproheptadine; Humans; Immunoglobulin E; Keratoconj

2019
Re: Compalati E, Canonica GW. Efficacy and safety of rupatadine for allergic rhino-conjunctivitis: a systematic review of randomized, double-blind, placebo-controlled studies with meta-analysis. Letter to the editor.
    Current medical research and opinion, 2013, Volume: 29, Issue:11

    Topics: Conjunctivitis, Allergic; Cyproheptadine; Histamine Antagonists; Humans; Rhinitis, Allergic, Perenni

2013
Re Letter to the editor re: Compalati E, Canonica GW. Efficacy and safety of rupatadine for allergic rhinoconjunctivitis: a systematic review of randomized, double-blind, placebo-controlled studies with meta-analysis. Curr Med Res Opin 2013 Jul 5.
    Current medical research and opinion, 2014, Volume: 30, Issue:2

    Topics: Conjunctivitis, Allergic; Cyproheptadine; Histamine Antagonists; Humans; Rhinitis, Allergic, Perenni

2014