cyproheptadine has been researched along with Cholestasis in 2 studies
Cyproheptadine: A serotonin antagonist and a histamine H1 blocker used as antipruritic, appetite stimulant, antiallergic, and for the post-gastrectomy dumping syndrome, etc.
cyproheptadine : The product resulting from the formal oxidative coupling of position 5 of 5H-dibenzo[a,d]cycloheptene with position 4 of 1-methylpiperidine resulting in the formation of a double bond between the two fragments. It is a sedating antihistamine with antimuscarinic and calcium-channel blocking actions. It is used (particularly as the hydrochloride sesquihydrate) for the relief of allergic conditions including rhinitis, conjunctivitis due to inhalant allergens and foods, urticaria and angioedema, and in pruritic skin disorders. Unlike other antihistamines, it is also a seratonin receptor antagonist, making it useful in conditions such as vascular headache and anorexia.
Cholestasis: Impairment of bile flow due to obstruction in small bile ducts (INTRAHEPATIC CHOLESTASIS) or obstruction in large bile ducts (EXTRAHEPATIC CHOLESTASIS).
| Excerpt | Relevance | Reference |
|---|---|---|
| "We report a patient in whom cyproheptadine-induced hepatitis was followed by prolonged cholestasis marked by elevation of serum alkaline phosphatase levels, gammaglutamyltransferase and bile acid levels, and disappearance of small bile ducts." | 7.67 | Prolonged cholestasis after cyproheptadine-induced acute hepatitis. ( Benhamou, JP; Degott, C; Geneve, J; Larrey, D; Machayekhi, JP; Pessayre, D, 1987) |
| "We report a patient in whom cyproheptadine-induced hepatitis was followed by prolonged cholestasis marked by elevation of serum alkaline phosphatase levels, gammaglutamyltransferase and bile acid levels, and disappearance of small bile ducts." | 3.67 | Prolonged cholestasis after cyproheptadine-induced acute hepatitis. ( Benhamou, JP; Degott, C; Geneve, J; Larrey, D; Machayekhi, JP; Pessayre, D, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Henry, DA | 1 |
| Lowe, JM | 1 |
| Donnelly, T | 1 |
| Larrey, D | 1 |
| Geneve, J | 1 |
| Pessayre, D | 1 |
| Machayekhi, JP | 1 |
| Degott, C | 1 |
| Benhamou, JP | 1 |
2 other studies available for cyproheptadine and Cholestasis
| Article | Year |
|---|---|
Jaundice during cyproheptadine treatment.
Topics: Adult; Cholestasis; Cyproheptadine; Female; Humans; Jaundice; Pruritus | 1978 |
Prolonged cholestasis after cyproheptadine-induced acute hepatitis.
Topics: Acute Disease; Adult; Chemical and Drug Induced Liver Injury; Cholestasis; Cyproheptadine; Female; H | 1987 |