cyproheptadine has been researched along with Chemical Dependence in 10 studies
Cyproheptadine: A serotonin antagonist and a histamine H1 blocker used as antipruritic, appetite stimulant, antiallergic, and for the post-gastrectomy dumping syndrome, etc.
cyproheptadine : The product resulting from the formal oxidative coupling of position 5 of 5H-dibenzo[a,d]cycloheptene with position 4 of 1-methylpiperidine resulting in the formation of a double bond between the two fragments. It is a sedating antihistamine with antimuscarinic and calcium-channel blocking actions. It is used (particularly as the hydrochloride sesquihydrate) for the relief of allergic conditions including rhinitis, conjunctivitis due to inhalant allergens and foods, urticaria and angioedema, and in pruritic skin disorders. Unlike other antihistamines, it is also a seratonin receptor antagonist, making it useful in conditions such as vascular headache and anorexia.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The hypertension, which peaked at 200/160 mm Hg and was associated with severe headache and diaphoresis, responded expeditiously to two initial intravenous doses of labetalol." | 3.67 | Pseudoephedrine-induced hypertensive emergency: treatment with labetalol. ( Mariani, PJ, 1986) |
| "Fluoxetine pretreatment, likewise, reduced responding in non-lesioned rats and had no observable effect in lesioned animals." | 1.27 | The effects of putative 5-hydroxytryptamine receptor active agents on D-amphetamine self-administration in controls and rats with 5,7-dihydroxytryptamine median forebrain bundle lesions. ( Leccese, AP; Lyness, WH, 1984) |
| "The cyproheptadine was initially prescribed to promote weight gain but its continued use seemed related to other psychological and/or pharmacological effects." | 1.27 | Cyproheptadine dependence associated with an atypical somatoform disorder. ( Craven, JL; Rodin, GM, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (90.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (10.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hardman, MI | 1 |
| Sprung, J | 1 |
| Weingarten, TN | 1 |
| Johnstone, EC | 1 |
| Ferrier, IN | 1 |
| Joske, DJ | 1 |
| Leccese, AP | 1 |
| Lyness, WH | 1 |
| Nickel, B | 1 |
| Herz, A | 1 |
| Jakovlev, V | 1 |
| Tibes, U | 1 |
| Kuhn, C | 1 |
| Bero, L | 1 |
| Ignar, D | 1 |
| Lurie, S | 1 |
| Field, E | 1 |
| Craven, JL | 1 |
| Rodin, GM | 1 |
| Mariani, PJ | 1 |
| Nurimoto, S | 1 |
| Friedman, AP | 1 |
2 reviews available for cyproheptadine and Chemical Dependence
| Article | Year |
|---|---|
Acute phenibut withdrawal: A comprehensive literature review and illustrative case report.
Topics: Akathisia, Drug-Induced; Baclofen; Cyproheptadine; Dexmedetomidine; Diphenhydramine; GABA-A Receptor | 2019 |
Neuroendocrine markers of CNS drug effects.
Topics: Animals; Anti-Anxiety Agents; Antidepressive Agents; Antipsychotic Agents; Central Nervous System Ag | 1980 |
8 other studies available for cyproheptadine and Chemical Dependence
| Article | Year |
|---|---|
Dystonic reaction to azatadine.
Topics: Adult; Cyproheptadine; Dystonia; Humans; Male; Substance-Related Disorders | 1984 |
The effects of putative 5-hydroxytryptamine receptor active agents on D-amphetamine self-administration in controls and rats with 5,7-dihydroxytryptamine median forebrain bundle lesions.
Topics: 5,7-Dihydroxytryptamine; Animals; Cyproheptadine; Dextroamphetamine; Fluoxetine; Humans; Male; Media | 1984 |
[Mechanism of action of the analgesic flupirtine].
Topics: Aminopyridines; Analgesics; Animals; Brain; Cyproheptadine; Fenclonine; Injections, Intraventricular | 1985 |
Endocrine consequences of perinatal methadone exposure.
Topics: Aging; Animals; Animals, Newborn; Cyproheptadine; Disease Models, Animal; Hypothalamo-Hypophyseal Sy | 1987 |
Cyproheptadine dependence associated with an atypical somatoform disorder.
Topics: Adult; Body Image; Crohn Disease; Cyproheptadine; Female; Humans; Somatoform Disorders; Substance-Re | 1987 |
Pseudoephedrine-induced hypertensive emergency: treatment with labetalol.
Topics: Adult; Cyproheptadine; Ephedrine; Humans; Hypertension; Infusions, Parenteral; Labetalol; Male; Subs | 1986 |
A simple method for evaluating physical dependence liability in rats.
Topics: Aminopyrine; Animals; Azepines; Body Weight; Codeine; Cyproheptadine; Dextropropoxyphene; Humans; Ma | 1973 |
Reflections on the treatment of headache.
Topics: Animals; Aspirin; Cyproheptadine; Ergotamine; Haplorhini; Headache; Hormones; Humans; Methysergide; | 1972 |