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cyproheptadine and Central Nervous System Diseases

cyproheptadine has been researched along with Central Nervous System Diseases in 3 studies

Cyproheptadine: A serotonin antagonist and a histamine H1 blocker used as antipruritic, appetite stimulant, antiallergic, and for the post-gastrectomy dumping syndrome, etc.
cyproheptadine : The product resulting from the formal oxidative coupling of position 5 of 5H-dibenzo[a,d]cycloheptene with position 4 of 1-methylpiperidine resulting in the formation of a double bond between the two fragments. It is a sedating antihistamine with antimuscarinic and calcium-channel blocking actions. It is used (particularly as the hydrochloride sesquihydrate) for the relief of allergic conditions including rhinitis, conjunctivitis due to inhalant allergens and foods, urticaria and angioedema, and in pruritic skin disorders. Unlike other antihistamines, it is also a seratonin receptor antagonist, making it useful in conditions such as vascular headache and anorexia.

Central Nervous System Diseases: Diseases of any component of the brain (including the cerebral hemispheres, diencephalon, brain stem, and cerebellum) or the spinal cord.

Research Excerpts

ExcerptRelevanceReference
"Cyproheptadine prevention of the neuropsychiatric adverse effects of an antiretroviral regimen including efavirenz has been evaluated in a randomized clinical trial."2.78Cyproheptadine for prevention of neuropsychiatric adverse effects of efavirenz: a randomized clinical trial. ( Akhondzadeh, S; Alimadadi, A; Dabaghzadeh, F; Ghaeli, P; Jafari, S; Khalili, H; Khazaeipour, Z, 2013)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (33.33)18.2507
2000's1 (33.33)29.6817
2010's1 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Dabaghzadeh, F1
Ghaeli, P1
Khalili, H1
Alimadadi, A1
Jafari, S1
Akhondzadeh, S1
Khazaeipour, Z1
Camelo-Nunes, IC1
Watemberg, NM1
Roth, KS1
Alehan, FK1
Epstein, CE1

Reviews

2 reviews available for cyproheptadine and Central Nervous System Diseases

ArticleYear
New antihistamines: a critical view.
    Jornal de pediatria, 2006, Volume: 82, Issue:5 Suppl

    Topics: Anti-Allergic Agents; Blood-Brain Barrier; Central Nervous System Diseases; Cetirizine; Child; Cypro

2006
Central anticholinergic syndrome on therapeutic doses of cyproheptadine.
    Pediatrics, 1999, Volume: 103, Issue:1

    Topics: Central Nervous System Diseases; Child; Cholinergic Antagonists; Cyproheptadine; Hallucinations; Hum

1999

Trials

1 trial available for cyproheptadine and Central Nervous System Diseases

ArticleYear
Cyproheptadine for prevention of neuropsychiatric adverse effects of efavirenz: a randomized clinical trial.
    AIDS patient care and STDs, 2013, Volume: 27, Issue:3

    Topics: Adult; Alkynes; Anti-HIV Agents; Benzoxazines; Central Nervous System Diseases; Cyclopropanes; Cypro

2013