cyproheptadine has been researched along with Brain Ischemia in 2 studies
Cyproheptadine: A serotonin antagonist and a histamine H1 blocker used as antipruritic, appetite stimulant, antiallergic, and for the post-gastrectomy dumping syndrome, etc.
cyproheptadine : The product resulting from the formal oxidative coupling of position 5 of 5H-dibenzo[a,d]cycloheptene with position 4 of 1-methylpiperidine resulting in the formation of a double bond between the two fragments. It is a sedating antihistamine with antimuscarinic and calcium-channel blocking actions. It is used (particularly as the hydrochloride sesquihydrate) for the relief of allergic conditions including rhinitis, conjunctivitis due to inhalant allergens and foods, urticaria and angioedema, and in pruritic skin disorders. Unlike other antihistamines, it is also a seratonin receptor antagonist, making it useful in conditions such as vascular headache and anorexia.
Brain Ischemia: Localized reduction of blood flow to brain tissue due to arterial obstruction or systemic hypoperfusion. This frequently occurs in conjunction with brain hypoxia (HYPOXIA, BRAIN). Prolonged ischemia is associated with BRAIN INFARCTION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This vasospasm was essentially unaffected by intravenous cyproheptadine." | 1.26 | Cerebrovascular responses to subarachnoid blood and serotonin in the monkey. ( Boisvert, DP; Grace, MG; Overton, TR; Reiffenstein, RJ; Weir, BK, 1979) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Boisvert, DP | 1 |
| Weir, BK | 1 |
| Overton, TR | 1 |
| Reiffenstein, RJ | 1 |
| Grace, MG | 1 |
| Sugio, K | 1 |
| Horigome, N | 1 |
| Inami, T | 1 |
| Tanaka, Y | 1 |
| Sakurai, M | 1 |
| Gotoh, M | 1 |
| Sakaguchi, T | 1 |
2 other studies available for cyproheptadine and Brain Ischemia
| Article | Year |
|---|---|
Cerebrovascular responses to subarachnoid blood and serotonin in the monkey.
Topics: Animals; Brain Ischemia; Cerebrovascular Circulation; Cyproheptadine; Disease Models, Animal; Female | 1979 |
Effects of pentobarbital and cyproheptadine on brain ischemia induced by bilateral occlusions of carotid arteries and vertebral arteries of second cervical vertebra in rats.
Topics: Animals; Brain Ischemia; Carotid Arteries; Cerebrovascular Circulation; Cyproheptadine; Electroencep | 1988 |