Page last updated: 2024-10-25

cyproheptadine and Bleeding

cyproheptadine has been researched along with Bleeding in 7 studies

Cyproheptadine: A serotonin antagonist and a histamine H1 blocker used as antipruritic, appetite stimulant, antiallergic, and for the post-gastrectomy dumping syndrome, etc.
cyproheptadine : The product resulting from the formal oxidative coupling of position 5 of 5H-dibenzo[a,d]cycloheptene with position 4 of 1-methylpiperidine resulting in the formation of a double bond between the two fragments. It is a sedating antihistamine with antimuscarinic and calcium-channel blocking actions. It is used (particularly as the hydrochloride sesquihydrate) for the relief of allergic conditions including rhinitis, conjunctivitis due to inhalant allergens and foods, urticaria and angioedema, and in pruritic skin disorders. Unlike other antihistamines, it is also a seratonin receptor antagonist, making it useful in conditions such as vascular headache and anorexia.

Research Excerpts

ExcerptRelevanceReference
"Furthermore, using a carotid artery thrombosis model, these agents prolonged the time for thrombotic occlusion in mice in vivo."1.40The antidepressant 5-HT2A receptor antagonists pizotifen and cyproheptadine inhibit serotonin-enhanced platelet function. ( Espinosa, EV; Karim, ZA; Khasawneh, FT; Lin, OA; Vemana, HP, 2014)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19905 (71.43)18.7374
1990's0 (0.00)18.2507
2000's1 (14.29)29.6817
2010's1 (14.29)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lin, OA1
Karim, ZA1
Vemana, HP1
Espinosa, EV1
Khasawneh, FT1
TAKAYASU, H1
YONESE, Y1
SUGIURA, H1
GORO, T2
KALAS, JP1
JACOBSON, ED1
Muhuri, D1
Dasgupta, SC1
Gomes, A1
Vargaftig, BB1
Bhargava, N1
Bonta, IL1
Hall, CE1
Ayachi, S1
Hall, O1

Other Studies

7 other studies available for cyproheptadine and Bleeding

ArticleYear
The antidepressant 5-HT2A receptor antagonists pizotifen and cyproheptadine inhibit serotonin-enhanced platelet function.
    PloS one, 2014, Volume: 9, Issue:1

    Topics: Adenosine Diphosphate; Animals; Antidepressive Agents; Blotting, Western; Calcium; Carotid Artery Th

2014
[IDIOPATHIC RENAL HEMORRHAGE AND SEROTONIN].
    Arerugi = [Allergy], 1964, Volume: 13

    Topics: Blood Chemical Analysis; Cholinesterases; Cyproheptadine; Fibrinolysin; Hemorrhage; Humans; Hydroxyi

1964
THE EFFECT OF VASOACTIVE ANTAGONISTS IN ENDOTOXIN SHOCK.
    American heart journal, 1964, Volume: 67

    Topics: Animals; Atropine; Blood Circulation; Blood Pressure; Blood Pressure Determination; Chloralose; Cypr

1964
Lethal, oedema, haemorrhagic activity of spotted butterfish (Scatophagus argus, Linn) sting extract and its neutralization by antiserum and pharmacological antagonists.
    Indian journal of experimental biology, 2005, Volume: 43, Issue:6

    Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Cyproheptadine; Edema; Edetic

2005
[Serotonin metabolism in patients with so-called essential renal bleeding].
    Nihon Hinyokika Gakkai zasshi. The japanese journal of urology, 1966, Volume: 57, Issue:10

    Topics: Adult; Aged; Aminocaproates; Cyproheptadine; Female; Hematuria; Hemorrhage; Humans; Hydroxyindoleace

1966
Haemorrhagic and permeability increasing effects of 'Bothrops jararaca' and other Crotalidae venoms as related to amine or kinin release.
    Agents and actions, 1974, Volume: 4, Issue:3

    Topics: Amines; Animals; Autacoids; Capillary Permeability; Cyproheptadine; Dose-Response Relationship, Drug

1974
Effect of cortisol and cyproheptadine on anaphylactoid and arthritic responses of the rat to dextran.
    Archives internationales de pharmacodynamie et de therapie, 1973, Volume: 201, Issue:2

    Topics: Acute Disease; Anaphylaxis; Animals; Arthritis; Chronic Disease; Cyproheptadine; Dextrans; Disease M

1973