cyproheptadine has been researched along with Atopic Hypersensitivity in 13 studies
Cyproheptadine: A serotonin antagonist and a histamine H1 blocker used as antipruritic, appetite stimulant, antiallergic, and for the post-gastrectomy dumping syndrome, etc.
cyproheptadine : The product resulting from the formal oxidative coupling of position 5 of 5H-dibenzo[a,d]cycloheptene with position 4 of 1-methylpiperidine resulting in the formation of a double bond between the two fragments. It is a sedating antihistamine with antimuscarinic and calcium-channel blocking actions. It is used (particularly as the hydrochloride sesquihydrate) for the relief of allergic conditions including rhinitis, conjunctivitis due to inhalant allergens and foods, urticaria and angioedema, and in pruritic skin disorders. Unlike other antihistamines, it is also a seratonin receptor antagonist, making it useful in conditions such as vascular headache and anorexia.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Cetirizine, 2." | 2.67 | Compared peripheral H1 inhibiting effects of cetirizine 2 HCl and loratadine. ( Coulie, P; Ghys, L; Rihoux, JP, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (61.54) | 18.7374 |
| 1990's | 5 (38.46) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Smith, H | 2 |
| Ross, JW | 1 |
| Spicer, BA | 2 |
| Inagaki, N | 1 |
| Sakurai, T | 1 |
| Abe, T | 1 |
| Musoh, K | 1 |
| Kawasaki, H | 1 |
| Tsunematsu, M | 1 |
| Nagai, H | 1 |
| Martel, RR | 1 |
| Klicius, J | 1 |
| Musoke, AJ | 1 |
| Williams, JF | 1 |
| Leid, RW | 1 |
| Kaliner, MA | 1 |
| Shall, L | 1 |
| Thompson, DA | 1 |
| Barkley, AS | 1 |
| Millard, LG | 1 |
| Andersson, M | 1 |
| Nolte, H | 1 |
| Baumgarten, C | 1 |
| Pipkorn, U | 1 |
| Rihoux, JP | 1 |
| Ghys, L | 1 |
| Coulie, P | 1 |
| Laycock, SM | 1 |
| Baird, AW | 1 |
| Cuthbert, AW | 1 |
| Dietz, AJ | 1 |
| Carlson, JD | 1 |
| Beck, CL | 1 |
| Feher, PJ | 1 |
| Kalz, F | 1 |
| Fink, JN | 1 |
2 reviews available for cyproheptadine and Atopic Hypersensitivity
| Article | Year |
|---|---|
Nonsedating antihistamines: pharmacology, clinical efficacy and adverse effects.
Topics: Astemizole; Cyproheptadine; Histamine H1 Antagonists; Humans; Hypersensitivity, Immediate; Loratadin | 1992 |
Treatment of urticaria and physical allergy.
Topics: Cold Temperature; Cyproheptadine; Diet Therapy; Drug Hypersensitivity; Environmental Exposure; Food | 1968 |
5 trials available for cyproheptadine and Atopic Hypersensitivity
| Article | Year |
|---|---|
Comparative inhibition profiles of three non-sedating antihistamines assessed by an extended Lewis model.
Topics: Adult; Analysis of Variance; Cetirizine; Cyproheptadine; Female; Histamine Antagonists; Histamine H1 | 1992 |
Suppressive effect of loratadine on allergen-induced histamine release in the nose.
Topics: Adolescent; Adult; Allergens; Cyproheptadine; Double-Blind Method; Female; Histamine H1 Antagonists; | 1991 |
Compared peripheral H1 inhibiting effects of cetirizine 2 HCl and loratadine.
Topics: Adult; Cetirizine; Cyproheptadine; Double-Blind Method; Drug Hypersensitivity; Female; Histamine; Hi | 1990 |
Effect of transdermal azatadine on reducing histamine-induced wheal area.
Topics: Administration, Oral; Administration, Topical; Adolescent; Adult; Cyproheptadine; Histamine; Humans; | 1986 |
Studies in vascular permeability of human skin bradykinin.
Topics: Aprotinin; Blood Vessels; Bradykinin; Cyproheptadine; Guanethidine; Histamine; Histamine Release; Hu | 1966 |
6 other studies available for cyproheptadine and Atopic Hypersensitivity
| Article | Year |
|---|---|
Rat passive peritoneal anaphylaxis following sensitisation with guinea pig antiserum: an immediate hypersensitivity reaction without histamine release.
Topics: Anaphylaxis; Animals; Antigens; Blood Proteins; Coloring Agents; Cyproheptadine; Guinea Pigs; Histam | 1980 |
Characterization of antihistamines using biphasic cutaneous reaction in BALB/c mice.
Topics: Animals; Cyproheptadine; Dermatitis, Allergic Contact; Diphenhydramine; Dose-Response Relationship, | 1998 |
Reagin-mediated hypersensitivity reaction in the rat hindpaw and its inhibition by antianaphylactic drugs.
Topics: Aminophylline; Animals; Cromolyn Sodium; Cyproheptadine; Edema; Hindlimb; Hypersensitivity, Immediat | 1977 |
Immunological response of the rat to infection with Taenia taeniaeformis. VI. The role of immediate hypersensitivity in resistance to reinfection.
Topics: Animals; Antibodies; Cyproheptadine; Histamine; Hypersensitivity, Immediate; Immunity, Maternally-Ac | 1978 |
The effects of drugs on leucocyte changes following the injection of antigen into the peritoneal cavities of actively sensitised rats.
Topics: Aminophylline; Animals; Antigens; Cromolyn Sodium; Cyproheptadine; Dexamethasone; Dextrans; Histamin | 1986 |
Neuronal involvement in type 1 hypersensitivity reactions in gut epithelia.
Topics: Animals; Cyproheptadine; Epithelium; Guinea Pigs; Hypersensitivity, Immediate; In Vitro Techniques; | 1987 |