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cyproheptadine and Appetite Disorders

cyproheptadine has been researched along with Appetite Disorders in 43 studies

Cyproheptadine: A serotonin antagonist and a histamine H1 blocker used as antipruritic, appetite stimulant, antiallergic, and for the post-gastrectomy dumping syndrome, etc.
cyproheptadine : The product resulting from the formal oxidative coupling of position 5 of 5H-dibenzo[a,d]cycloheptene with position 4 of 1-methylpiperidine resulting in the formation of a double bond between the two fragments. It is a sedating antihistamine with antimuscarinic and calcium-channel blocking actions. It is used (particularly as the hydrochloride sesquihydrate) for the relief of allergic conditions including rhinitis, conjunctivitis due to inhalant allergens and foods, urticaria and angioedema, and in pruritic skin disorders. Unlike other antihistamines, it is also a seratonin receptor antagonist, making it useful in conditions such as vascular headache and anorexia.

Research Excerpts

ExcerptRelevanceReference
" This research evaluates the preventive effects of cyproheptadine on sleeping and appetite disorders induced by methylphenidate in ADHD children."9.30Preventive effect of cyproheptadine on sleep and appetite disorders induced by methylphenidate: an exploratory randomised, double-blinded, placebo-controlled clinical trial. ( Elyasi, S; Kadkhoda Mezerji, F; Mohammadpour, AH; Moharreri, F, 2019)
" To determine whether serotonergic mechanisms are involved in the stress- and oestrogen-induced anorexia, the 5-HT antagonist cyproheptadine was given to ovariectomized rats that were immobilized and treated with oestradiol benzoate."7.67The influence of cyproheptadine on immobilization and oestradiol benzoate induced anorexia in ovariectomized rats. ( Donohoe, TP; Haslam, C; Stevens, R, 1987)
" This research evaluates the preventive effects of cyproheptadine on sleeping and appetite disorders induced by methylphenidate in ADHD children."5.30Preventive effect of cyproheptadine on sleep and appetite disorders induced by methylphenidate: an exploratory randomised, double-blinded, placebo-controlled clinical trial. ( Elyasi, S; Kadkhoda Mezerji, F; Mohammadpour, AH; Moharreri, F, 2019)
"This is a retrospective chart review of 39 patients less than three years of age who were prescribed cyproheptadine for feeding intolerance or vomiting and had follow-up information available."3.83A retrospective review of cyproheptadine for feeding intolerance in children less than three years of age: effects and side effects. ( Butler, DR; Kaul, A; Meinzen-Derr, J; Merhar, SL; Mukkada, VA; Pentiuk, SP, 2016)
" To determine whether serotonergic mechanisms are involved in the stress- and oestrogen-induced anorexia, the 5-HT antagonist cyproheptadine was given to ovariectomized rats that were immobilized and treated with oestradiol benzoate."3.67The influence of cyproheptadine on immobilization and oestradiol benzoate induced anorexia in ovariectomized rats. ( Donohoe, TP; Haslam, C; Stevens, R, 1987)
"Cyproheptadine is a safe treatment option in patients with poor appetite."3.01Efficacy and Tolerability of Cyproheptadine in Poor Appetite: A Multicenter, Randomized, Double-blind, Placebo-controlled Study. ( Cho, B; Cho, KH; Cho, YG; Kim, SY; Lee, JW; Park, YG; Yun, JM, 2021)
"Increased research focusing on the eating disorders has put the clinician on firmer ground when choosing appropriate psychopharmacologic treatments."2.37Pharmacologic treatment of eating disorders. ( Gwirtsman, H; Jimerson, DC; Kaye, W; Weintraub, M, 1984)

Research

Studies (43)

TimeframeStudies, this research(%)All Research%
pre-199037 (86.05)18.7374
1990's2 (4.65)18.2507
2000's1 (2.33)29.6817
2010's2 (4.65)24.3611
2020's1 (2.33)2.80

Authors

AuthorsStudies
Kim, SY1
Yun, JM1
Lee, JW1
Cho, YG1
Cho, KH1
Park, YG1
Cho, B1
Kadkhoda Mezerji, F1
Moharreri, F1
Mohammadpour, AH1
Elyasi, S1
Merhar, SL1
Pentiuk, SP1
Mukkada, VA1
Meinzen-Derr, J1
Kaul, A1
Butler, DR1
BERGEN, SS1
Gwirtsman, H1
Kaye, W1
Weintraub, M1
Jimerson, DC1
Johnson, C1
Stuckey, M1
Mitchell, J1
Halmi, KA1
Herzog, DB1
Rosenberg, JM1
Kirschenbaum, HL1
Saleem, G1
Ritz, J1
Martino, FP1
Szórády, I1
Blaustein, BS1
Gaeta, TJ1
Balentine, JR1
Gindi, M1
Jatoi, A1
Loprinzi, CL2
Berger, M1
White, J1
Travis, LB1
Brouhard, BH1
Cunningham, RJ1
Patnode, R1
Petrusick, T1
Giordano, C1
Perrotti, G1
Pawlowski, GJ1
Rahman, KM1
Kardinal, CG1
Schaid, DJ1
Hass, AC1
Dose, AM1
Athmann, LM1
Mailliard, JA1
McCormack, GW1
Gerstner, JB1
Schray, MF1
Haslam, C1
Stevens, R1
Donohoe, TP1
Autry, JH1
Stover, ES1
Reatig, N1
Casper, R1
Mertz, DP2
Stelzer, M1
Mölleney, W1
Mainguet, P1
Di Marzo, G1
Kibel, MA1
Sardesai, HV1
Melinkeri, RD1
Diwate, AB1
Karandikar, RS1
Joshi, PV1
Hermans, W1
Juillard, E1
Francini, F1
Santana, JG1
Kitrosen, J1
Motta, W1
Panzetti, G1
Budetta, M1
Benevento, L1
Ruocco, C1
Pototschnig, C1
Serafini, L1
Hilt, G1
Bungeroth, KA1
Kielhorn, E1
Kielhorn, A1
Beccari, A1
Rondinini, B1
Diehl, LW1
Martino, A1
Musella, U1
Ruffolo, A1
Gebhart, E1
Flatberg, P1
Murken, JD1

Reviews

5 reviews available for cyproheptadine and Appetite Disorders

ArticleYear
Pharmacologic treatment of eating disorders.
    The Psychiatric clinics of North America, 1984, Volume: 7, Issue:4

    Topics: Anorexia Nervosa; Anticonvulsants; Antidepressive Agents; Antidepressive Agents, Tricyclic; Central

1984
Psychopharmacological treatment of anorexia nervosa and bulimia. Review and synthesis.
    The Journal of nervous and mental disease, 1983, Volume: 171, Issue:9

    Topics: Adrenocorticotropic Hormone; Anorexia Nervosa; Antidepressive Agents, Tricyclic; Chlorpromazine; Cyp

1983
The state of research in anorexia nervosa and bulimia.
    Psychiatric developments, 1983,Autumn, Volume: 1, Issue:3

    Topics: Adolescent; Adult; Age Factors; Amenorrhea; Anorexia Nervosa; Behavior Therapy; Body Image; Body Wei

1983
Pharmacotherapy of anorexia nervosa and bulimia.
    Pediatric annals, 1984, Volume: 13, Issue:12

    Topics: Amitriptyline; Anorexia Nervosa; Antidepressive Agents, Tricyclic; Chlorpromazine; Clinical Trials a

1984
An update: cancer-associated anorexia as a treatment target.
    Current opinion in clinical nutrition and metabolic care, 2001, Volume: 4, Issue:3

    Topics: Animals; Anorexia; Appetite; Appetite Regulation; Clinical Trials as Topic; Cyproheptadine; Dexameth

2001

Trials

16 trials available for cyproheptadine and Appetite Disorders

ArticleYear
Efficacy and Tolerability of Cyproheptadine in Poor Appetite: A Multicenter, Randomized, Double-blind, Placebo-controlled Study.
    Clinical therapeutics, 2021, Volume: 43, Issue:10

    Topics: Adult; Aged; Appetite; Appetite Stimulants; Child; Cyproheptadine; Double-Blind Method; Feeding and

2021
Preventive effect of cyproheptadine on sleep and appetite disorders induced by methylphenidate: an exploratory randomised, double-blinded, placebo-controlled clinical trial.
    International journal of psychiatry in clinical practice, 2019, Volume: 23, Issue:1

    Topics: Attention Deficit Disorder with Hyperactivity; Central Nervous System Stimulants; Child; Child, Pres

2019
Pharmacotherapy of anorexia nervosa and bulimia.
    Pediatric annals, 1984, Volume: 13, Issue:12

    Topics: Amitriptyline; Anorexia Nervosa; Antidepressive Agents, Tricyclic; Chlorpromazine; Clinical Trials a

1984
Cyproheptadine: weight-gain and appetite stimulation in essential anorexic adults.
    Current therapeutic research, clinical and experimental, 1975, Volume: 18, Issue:5

    Topics: Adolescent; Adult; Anorexia; Appetite; Body Weight; Clinical Trials as Topic; Cyproheptadine; Feedin

1975
Appetite stimulation and weight gain with cyproheptadine (periactin) in tuberculosis patients (double-blind clinical study).
    The Medical journal of Malaysia, 1975, Volume: 29, Issue:4

    Topics: Adolescent; Adult; Aged; Anorexia; Body Weight; Clinical Trials as Topic; Cyproheptadine; Feeding an

1975
A controlled trial of cyproheptadine in cancer patients with anorexia and/or cachexia.
    Cancer, 1990, Jun-15, Volume: 65, Issue:12

    Topics: Adult; Aged; Aged, 80 and over; Anorexia; Appetite; Cachexia; Cyproheptadine; Double-Blind Method; F

1990
Anorexia nervosa and bulimia.
    Annual review of public health, 1986, Volume: 7

    Topics: Adolescent; Anorexia Nervosa; Antidepressive Agents, Tricyclic; Behavior Therapy; Clinical Trials as

1986
Effect of cyproheptadine on anorexia and loss of weight in adults.
    The Practitioner, 1972, Volume: 208, Issue:248

    Topics: Adult; Body Weight; Clinical Trials as Topic; Cyproheptadine; Feeding and Eating Disorders; Humans;

1972
[Effects of cyproheptadine in a sample of children in the second age of childhood].
    Minerva pediatrica, 1973, May-26, Volume: 25, Issue:19

    Topics: Appetite; Body Weight; Child; Child, Preschool; Clinical Trials as Topic; Cyproheptadine; Feeding an

1973
Appetite and weight gain in children: a double-blind trial using cyproheptadine and methandrostenolone.
    The Central African journal of medicine, 1969, Volume: 15, Issue:11

    Topics: Adolescent; Body Weight; Child; Child, Preschool; Clinical Trials as Topic; Cyproheptadine; Feeding

1969
A weight-promoting drug.
    The Practitioner, 1970, Volume: 205, Issue:225

    Topics: Adolescent; Adult; Aged; Appetite; Body Weight; Child; Clinical Trials as Topic; Cyproheptadine; Fee

1970
Weight gain with cyproheptadine hydrochloride ('Periactin'). A double blind trial in underweight medical students.
    Indian journal of medical sciences, 1970, Volume: 24, Issue:11

    Topics: Adolescent; Adult; Body Weight; Clinical Trials as Topic; Cyproheptadine; Feeding and Eating Disorde

1970
[Clinical evaluation of buclizine for underweight patients].
    Bruxelles medical, 1971, Volume: 51, Issue:4

    Topics: Adult; Body Weight; Clinical Trials as Topic; Cyproheptadine; Feeding and Eating Disorders; Humans;

1971
[Stimulation of the appetite in children: comparison between the action of cyproheptadine and a placebo].
    Revue medicale de la Suisse romande, 1971, Volume: 91, Issue:8

    Topics: Adolescent; Age Factors; Child; Child, Preschool; Clinical Trials as Topic; Cyproheptadine; Feeding

1971
[Increase of appetite by Nuran in liver diseases].
    Munchener medizinische Wochenschrift (1950), 1971, Jan-15, Volume: 113, Issue:3

    Topics: Adolescent; Adult; Aged; Appetite; Appetite Regulation; Body Weight; Cyproheptadine; Fatty Liver; Fe

1971
[Treatment of underweight and appetite loss with antiallergic agent cyproheptadine].
    Therapie der Gegenwart, 1971, Volume: 110, Issue:5

    Topics: Body Weight; Cyproheptadine; Feeding and Eating Disorders; Humans

1971

Other Studies

23 other studies available for cyproheptadine and Appetite Disorders

ArticleYear
A retrospective review of cyproheptadine for feeding intolerance in children less than three years of age: effects and side effects.
    Acta paediatrica (Oslo, Norway : 1992), 2016, Volume: 105, Issue:8

    Topics: Child, Preschool; Cholinergic Antagonists; Cyproheptadine; Feeding and Eating Disorders; Female; His

2016
APPETITE STIMULATING PROPERTIES OF CYPROHEPTADINE.
    American journal of diseases of children (1960), 1964, Volume: 108

    Topics: Adolescent; Appetite; Asthma; Biomedical Research; Blood Glucose; Child; Cyproheptadine; Feeding and

1964
Benoxaprofen and cyproheptadine.
    The Journal of the Medical Society of New Jersey, 1982, Volume: 79, Issue:5

    Topics: Adolescent; Adult; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Child; Child, Preschool; Cyprohe

1982
The importance of Peritol in paediatrics.
    Therapia Hungarica (English edition), 1982, Volume: 30, Issue:1

    Topics: Anorexia; Child; Child, Preschool; Cyproheptadine; Feeding and Eating Disorders; Humans; Infant

1982
Cyproheptadine-induced central anticholinergic syndrome in a child: a case report.
    Pediatric emergency care, 1995, Volume: 11, Issue:4

    Topics: Adolescent; Cholinergic Antagonists; Confusion; Cyproheptadine; Drug Overdose; Feeding and Eating Di

1995
Toxic psychosis due to cyproheptadine in a child on hemodialysis: a case report.
    Clinical nephrology, 1977, Volume: 7, Issue:1

    Topics: Child; Cyproheptadine; Feeding and Eating Disorders; Humans; Male; Psychoses, Substance-Induced; Ren

1977
[Clinical studies of the effects of treatment with a combination of carnitine and cobamamide in infantile anorexia].
    La Clinica terapeutica, 1979, Jan-15, Volume: 88, Issue:1

    Topics: Anorexia; Carnitine; Child; Child, Preschool; Cobamides; Cyproheptadine; Drug Combinations; Drug Eva

1979
The influence of cyproheptadine on immobilization and oestradiol benzoate induced anorexia in ovariectomized rats.
    Psychopharmacology, 1987, Volume: 93, Issue:2

    Topics: Animals; Anorexia; Cyproheptadine; Estradiol; Feeding and Eating Disorders; Female; Immobilization;

1987
[Mechanism of the appetite and body weight increasing effect of cyproheptadine. I. Clinical experience and hormone iodine studies].
    Klinische Wochenschrift, 1969, Nov-15, Volume: 47, Issue:22

    Topics: Adult; Aged; Appetite; Asthenia; Body Weight; Cyproheptadine; Emaciation; Feeding and Eating Disorde

1969
[Therapy of thinness].
    Minerva medica, 1972, Apr-25, Volume: 63, Issue:31

    Topics: Body Weight; Cyproheptadine; Emaciation; Feeding and Eating Disorders; Fructose; Glucose; Growth; Hu

1972
[Therapy of underweight].
    Zeitschrift fur Allgemeinmedizin, 1972, Apr-30, Volume: 48, Issue:12

    Topics: Adolescent; Adult; Aged; Body Weight; Child; Child, Preschool; Cyproheptadine; Emaciation; Feeding a

1972
[Cyproheptadine, an antihistamine and serotonin antagonist acting on body weight: preliminary report].
    Minerva medica, 1968, Jul-11, Volume: 59, Issue:55

    Topics: Adolescent; Adult; Aged; Anorexia Nervosa; Body Weight; Child; Child, Preschool; Cyproheptadine; Fee

1968
[On the anti-anorexic and eutrophic activity of cyproheptadine in children].
    Minerva medica, 1969, Jun-06, Volume: 60, Issue:45

    Topics: Anorexia Nervosa; Body Weight; Child, Preschool; Cyproheptadine; Feeding and Eating Disorders; Femal

1969
[Treatment of infantile anorexia with cyproheptadine. Trials in congenital and dystrophic diseases].
    Minerva medica, 1969, Jun-13, Volume: 60, Issue:47

    Topics: Cyproheptadine; Feeding and Eating Disorders; Female; Humans; Infant; Infant Nutrition Disorders; In

1969
[Clinical observations on antianorexic activity of cyproheptadine].
    Minerva pediatrica, 1968, May-12, Volume: 20, Issue:19

    Topics: Body Weight; Child; Child, Preschool; Cyproheptadine; Feeding and Eating Disorders; Female; Growth;

1968
Cyproheptadine as an appetite stimulant.
    Drug and therapeutics bulletin, 1970, Aug-28, Volume: 8, Issue:18

    Topics: Adult; Aged; Animals; Appetite; Body Weight; Cats; Child; Cyproheptadine; Dogs; Feeding and Eating D

1970
[Nuran, a drug for the treatment of deficiency dystrophies and anorexia in children].
    Deutsches medizinisches Journal, 1970, Volume: 21, Issue:16

    Topics: Child, Preschool; Cyproheptadine; Feeding and Eating Disorders; Female; Humans; Infant; Infant Nutri

1970
[Trial in 40 children of cyproheptadine as an appetite stimulant].
    Minerva pediatrica, 1971, Feb-25, Volume: 23, Issue:8

    Topics: Child; Child, Preschool; Cyproheptadine; Feeding and Eating Disorders; Humans

1971
[On the clinical use of cyproheptadine as an anti-anorexic agent and its effects on the nutritional state].
    Minerva medica, 1971, May-12, Volume: 62, Issue:38

    Topics: Adolescent; Adult; Aged; Anorexia Nervosa; Appetite; Body Weight; Child; Child, Preschool; Cyprohept

1971
Cyproheptadine (Periactin).
    The Medical letter on drugs and therapeutics, 1971, Mar-05, Volume: 13, Issue:5

    Topics: Adolescent; Body Weight; Child; Child, Preschool; Cyproheptadine; Feeding and Eating Disorders; Huma

1971
[Damage to chromosomes through appetite stimulants].
    Deutsche medizinische Wochenschrift (1946), 1971, Sep-03, Volume: 96, Issue:36

    Topics: Chromosome Aberrations; Cyproheptadine; Feeding and Eating Disorders; Humans

1971
[Periactin as an appetite stimulants].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1971, Aug-10, Volume: 91, Issue:21

    Topics: Adult; Cyproheptadine; Feeding and Eating Disorders; Humans; Middle Aged

1971
[Chromosome damage caused by appetite inducers?].
    Deutsche medizinische Wochenschrift (1946), 1971, Oct-22, Volume: 96, Issue:43

    Topics: Child; Chromosomes; Cyproheptadine; Feeding and Eating Disorders; Humans; In Vitro Techniques; Lymph

1971