cyproheptadine has been researched along with Anorexia in 23 studies
Cyproheptadine: A serotonin antagonist and a histamine H1 blocker used as antipruritic, appetite stimulant, antiallergic, and for the post-gastrectomy dumping syndrome, etc.
cyproheptadine : The product resulting from the formal oxidative coupling of position 5 of 5H-dibenzo[a,d]cycloheptene with position 4 of 1-methylpiperidine resulting in the formation of a double bond between the two fragments. It is a sedating antihistamine with antimuscarinic and calcium-channel blocking actions. It is used (particularly as the hydrochloride sesquihydrate) for the relief of allergic conditions including rhinitis, conjunctivitis due to inhalant allergens and foods, urticaria and angioedema, and in pruritic skin disorders. Unlike other antihistamines, it is also a seratonin receptor antagonist, making it useful in conditions such as vascular headache and anorexia.
Anorexia: The lack or loss of APPETITE accompanied by an aversion to food and the inability to eat. It is the defining characteristic of the disorder ANOREXIA NERVOSA.
| Excerpt | Relevance | Reference |
|---|---|---|
| " To determine whether serotonergic mechanisms are involved in the stress- and oestrogen-induced anorexia, the 5-HT antagonist cyproheptadine was given to ovariectomized rats that were immobilized and treated with oestradiol benzoate." | 7.67 | The influence of cyproheptadine on immobilization and oestradiol benzoate induced anorexia in ovariectomized rats. ( Donohoe, TP; Haslam, C; Stevens, R, 1987) |
| "Cachexia occurs in the majority of cancer patients before death." | 3.77 | Clinical management of anorexia and cachexia in patients with advanced cancer. ( Bruera, E, 1992) |
| "Anorexia and cachexia are common clinical problems of many patients with advanced cancer." | 3.76 | Alleviation of cancer anorexia and cachexia: studies of the Mayo Clinic and the North Central Cancer Treatment Group. ( Burch, PA; Ellison, NM; Goldberg, RM; Loprinzi, CL; Michalak, JC, 1990) |
| " Alternative managements by prescribing cyproheptadine as an appetite stimulant resulted in significant improvement of feeding behaviors and weight gain." | 3.75 | Successful treatment in a child with feeding problems and growth failure. ( Benjasuwantep, B, 2009) |
| " To determine whether serotonergic mechanisms are involved in the stress- and oestrogen-induced anorexia, the 5-HT antagonist cyproheptadine was given to ovariectomized rats that were immobilized and treated with oestradiol benzoate." | 3.67 | The influence of cyproheptadine on immobilization and oestradiol benzoate induced anorexia in ovariectomized rats. ( Donohoe, TP; Haslam, C; Stevens, R, 1987) |
| "Cachexia is a frequent and devastating complication of advanced cancer." | 2.39 | Anorexia and cachexia in advanced cancer patients. ( Bruera, E; Vigano, A; Watanabe, S, 1994) |
| "Cancer cachexia is highly prevalent in patients with advanced cancer." | 2.38 | Is the pharmacological treatment of cancer cachexia possible? ( Bruera, E, 1993) |
| "The cyproheptadine was discontinued and the urinary retention disappeared." | 1.29 | [Acute urine retention: a rare mode of revelation of cervico-dorsal syringomyelia caused by cyproheptadine]. ( Bensman, A; Forin, V; Houang, M; Leroy, B; Sinnassamy, P, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (34.78) | 18.7374 |
| 1990's | 9 (39.13) | 18.2507 |
| 2000's | 3 (13.04) | 29.6817 |
| 2010's | 2 (8.70) | 24.3611 |
| 2020's | 1 (4.35) | 2.80 |
| Authors | Studies |
|---|---|
| McTavish, D | 1 |
| Thornton, J | 1 |
| Kasvis, P | 1 |
| Vigano, M | 1 |
| Vigano, A | 2 |
| Chinuck, R | 1 |
| Dewar, J | 1 |
| Baldwin, DR | 2 |
| Hendron, E | 1 |
| Benjasuwantep, B | 1 |
| MATHOV, E | 1 |
| Chinuck, RS | 1 |
| Fortnum, H | 1 |
| Szórády, I | 1 |
| Blavet, N | 1 |
| DeFeudis, FV | 1 |
| Clostre, F | 1 |
| Lerman-Sagie, T | 1 |
| Mimouni, M | 1 |
| Muranjan, MN | 1 |
| Mordekar, SR | 1 |
| Bava, HS | 1 |
| Alavi, S | 1 |
| Kher, AS | 1 |
| Nadkarni, UB | 1 |
| Kamat, JR | 1 |
| Houang, M | 1 |
| Leroy, B | 1 |
| Forin, V | 1 |
| Sinnassamy, P | 1 |
| Bensman, A | 1 |
| Bruera, E | 3 |
| Watanabe, S | 1 |
| Jatoi, A | 1 |
| Loprinzi, CL | 4 |
| Giordano, C | 1 |
| Perrotti, G | 1 |
| Pawlowski, GJ | 1 |
| Rahman, KM | 1 |
| Thirlby, RC | 1 |
| Kardinal, CG | 1 |
| Schaid, DJ | 1 |
| Hass, AC | 1 |
| Dose, AM | 2 |
| Athmann, LM | 1 |
| Mailliard, JA | 1 |
| McCormack, GW | 1 |
| Gerstner, JB | 1 |
| Schray, MF | 1 |
| Ellison, NM | 1 |
| Goldberg, RM | 1 |
| Michalak, JC | 1 |
| Burch, PA | 1 |
| Miser, AW | 1 |
| Kardinal, C | 1 |
| Everson, LK | 1 |
| Ahlquist, DA | 1 |
| Moertel, CG | 1 |
| Haslam, C | 1 |
| Stevens, R | 1 |
| Donohoe, TP | 1 |
9 reviews available for cyproheptadine and Anorexia
| Article | Year |
|---|---|
Appetite stimulants for people with cystic fibrosis.
Topics: Adult; Anorexia; Anti-Bacterial Agents; Appetite Stimulants; Child; Cyproheptadine; Cystic Fibrosis; | 2022 |
Health-related quality of life across cancer cachexia stages.
Topics: Adrenal Cortex Hormones; Anorexia; Appetite Stimulants; Cachexia; Cannabinoids; Cyproheptadine; Fema | 2019 |
Appetite stimulants for people with cystic fibrosis.
Topics: Anorexia; Appetite; Appetite Stimulants; Body Mass Index; Cyproheptadine; Cystic Fibrosis; Humans; M | 2014 |
Appetite stimulants in cystic fibrosis: a systematic review.
Topics: Anorexia; Appetite Stimulants; Body Weight; Cyproheptadine; Cystic Fibrosis; Dronabinol; Gastrointes | 2007 |
Is the pharmacological treatment of cancer cachexia possible?
Topics: Adrenal Cortex Hormones; Anorexia; Antineoplastic Agents; Cachexia; Cannabinoids; Clinical Protocols | 1993 |
Anorexia and cachexia in advanced cancer patients.
Topics: Adrenal Cortex Hormones; Animals; Anorexia; Antineoplastic Agents; Cachexia; Cannabinoids; Clinical | 1994 |
An update: cancer-associated anorexia as a treatment target.
Topics: Animals; Anorexia; Appetite; Appetite Regulation; Clinical Trials as Topic; Cyproheptadine; Dexameth | 2001 |
Clinical management of anorexia and cachexia in patients with advanced cancer.
Topics: Anorexia; Cachexia; Cannabinoids; Cyproheptadine; Humans; Hydrazines; Megestrol; Megestrol Acetate; | 1992 |
Alleviation of cancer anorexia and cachexia: studies of the Mayo Clinic and the North Central Cancer Treatment Group.
Topics: Anorexia; Cachexia; Cyproheptadine; Dexamethasone; Double-Blind Method; Humans; Hydrazines; Neoplasm | 1990 |
6 trials available for cyproheptadine and Anorexia
| Article | Year |
|---|---|
Cyproheptadine: weight-gain and appetite stimulation in essential anorexic adults.
Topics: Adolescent; Adult; Anorexia; Appetite; Body Weight; Clinical Trials as Topic; Cyproheptadine; Feedin | 1975 |
Appetite stimulation and weight gain with cyproheptadine (periactin) in tuberculosis patients (double-blind clinical study).
Topics: Adolescent; Adult; Aged; Anorexia; Body Weight; Clinical Trials as Topic; Cyproheptadine; Feeding an | 1975 |
Clinical management of anorexia and cachexia in patients with advanced cancer.
Topics: Anorexia; Cachexia; Cannabinoids; Cyproheptadine; Humans; Hydrazines; Megestrol; Megestrol Acetate; | 1992 |
A controlled trial of cyproheptadine in cancer patients with anorexia and/or cachexia.
Topics: Adult; Aged; Aged, 80 and over; Anorexia; Appetite; Cachexia; Cyproheptadine; Double-Blind Method; F | 1990 |
Alleviation of cancer anorexia and cachexia: studies of the Mayo Clinic and the North Central Cancer Treatment Group.
Topics: Anorexia; Cachexia; Cyproheptadine; Dexamethasone; Double-Blind Method; Humans; Hydrazines; Neoplasm | 1990 |
Cancer control research in the North Central Cancer Treatment Group (NCCTG).
Topics: Allopurinol; Anorexia; Antineoplastic Agents; Cachexia; Clinical Trials as Topic; Colorectal Neoplas | 1989 |
10 other studies available for cyproheptadine and Anorexia
| Article | Year |
|---|---|
Successful treatment in a child with feeding problems and growth failure.
Topics: Anorexia; Child, Preschool; Cyproheptadine; Feeding Behavior; Growth Disorders; Humans; Male; Seroto | 2009 |
[Poteniation of dexamethasone and cyproheptadine. Their use in allergic patients with anorexia and malnutrition].
Topics: Anorexia; Anorexia Nervosa; Anti-Allergic Agents; Cyproheptadine; Dexamethasone; Histamine H1 Antago | 1962 |
The importance of Peritol in paediatrics.
Topics: Anorexia; Child; Child, Preschool; Cyproheptadine; Feeding and Eating Disorders; Humans; Infant | 1982 |
Inhibition of food intake in the rat by cyproheptadine.
Topics: Animals; Anorexia; Appetite Depressants; Cyproheptadine; Dose-Response Relationship, Drug; Eating; K | 1982 |
Reversal of anorexia in a child with partial ornithine transcarbamylase deficiency by cyproheptadine therapy.
Topics: Anorexia; Child; Cyproheptadine; Female; Humans; Ornithine Carbamoyltransferase Deficiency Disease; | 1995 |
Cyproheptadine in severe anorexia.
Topics: Anorexia; Child, Preschool; Cyproheptadine; Female; Humans; Tuberculosis, Meningeal; Weight Gain | 1994 |
[Acute urine retention: a rare mode of revelation of cervico-dorsal syringomyelia caused by cyproheptadine].
Topics: Acute Disease; Anorexia; Child, Preschool; Cyproheptadine; Female; Humans; Magnetic Resonance Imagin | 1994 |
[Clinical studies of the effects of treatment with a combination of carnitine and cobamamide in infantile anorexia].
Topics: Anorexia; Carnitine; Child; Child, Preschool; Cobamides; Cyproheptadine; Drug Combinations; Drug Eva | 1979 |
Toward a treatment for anorexia and cachexia in patients with cancer.
Topics: Anorexia; Appetite Regulation; Cachexia; Cyproheptadine; Dexamethasone; Humans; Megestrol; Megestrol | 1991 |
The influence of cyproheptadine on immobilization and oestradiol benzoate induced anorexia in ovariectomized rats.
Topics: Animals; Anorexia; Cyproheptadine; Estradiol; Feeding and Eating Disorders; Female; Immobilization; | 1987 |