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cyproheptadine and Anorexia Nervosa

cyproheptadine has been researched along with Anorexia Nervosa in 34 studies

Cyproheptadine: A serotonin antagonist and a histamine H1 blocker used as antipruritic, appetite stimulant, antiallergic, and for the post-gastrectomy dumping syndrome, etc.
cyproheptadine : The product resulting from the formal oxidative coupling of position 5 of 5H-dibenzo[a,d]cycloheptene with position 4 of 1-methylpiperidine resulting in the formation of a double bond between the two fragments. It is a sedating antihistamine with antimuscarinic and calcium-channel blocking actions. It is used (particularly as the hydrochloride sesquihydrate) for the relief of allergic conditions including rhinitis, conjunctivitis due to inhalant allergens and foods, urticaria and angioedema, and in pruritic skin disorders. Unlike other antihistamines, it is also a seratonin receptor antagonist, making it useful in conditions such as vascular headache and anorexia.

Anorexia Nervosa: An eating disorder that is characterized by the lack or loss of APPETITE, known as ANOREXIA. Other features include excess fear of becoming OVERWEIGHT; BODY IMAGE disturbance; significant WEIGHT LOSS; refusal to maintain minimal normal weight; and AMENORRHEA. This disorder occurs most frequently in adolescent females. (APA, Thesaurus of Psychological Index Terms, 1994)

Research Excerpts

ExcerptRelevanceReference
"In three hospitals 81 female patients satisfying rigorous diagnostic criteria for anorexia nervosa were randomly allocated to one of four treatment combinations of cyproheptadine and placebo with behaviour therapy and no behaviour therapy."9.04Cyproheptadine in anorexia nervosa. ( Casper, RC; Davis, JM; Eckert, ED; Goldberg, SC; Halmi, KA, 1979)
"In three hospitals 81 female patients satisfying rigorous diagnostic criteria for anorexia nervosa were randomly allocated to one of four treatment combinations of cyproheptadine and placebo with behaviour therapy and no behaviour therapy."5.04Cyproheptadine in anorexia nervosa. ( Casper, RC; Davis, JM; Eckert, ED; Goldberg, SC; Halmi, KA, 1979)
"Increased research focusing on the eating disorders has put the clinician on firmer ground when choosing appropriate psychopharmacologic treatments."2.37Pharmacologic treatment of eating disorders. ( Gwirtsman, H; Jimerson, DC; Kaye, W; Weintraub, M, 1984)

Research

Studies (34)

TimeframeStudies, this research(%)All Research%
pre-199031 (91.18)18.7374
1990's1 (2.94)18.2507
2000's1 (2.94)29.6817
2010's1 (2.94)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Harrison, ME1
Norris, ML1
Robinson, A1
Spettigue, W1
Morrissey, M1
Isserlin, L1
Treasure, J1
Schmidt, U1
MATHOV, E1
Halmi, KA14
Eckert, E2
Falk, JR2
Rockwell, WJ2
Nishita, JK1
Ellinwood, EH2
Gwirtsman, H1
Kaye, W2
Weintraub, M1
Jimerson, DC1
Dougherty, GG1
Brodie, HK1
Johnson, C1
Stuckey, M1
Mitchell, J1
Herzog, DB1
Eckert, ED6
Goldberg, SC6
Casper, RC5
Davis, JM6
Roper, M2
Weltzin, TE1
McCabe, E1
Flynn, D1
Halmi, K1
Sherman, BS1
Kennedy, KA1
Fischer, LJ1
Dekirmenjian, H1
Casper, R2
Goldberg, S1
Marchi, P1
Cohen, J2
LaDu, TJ1
Autry, JH1
Stover, ES1
Reatig, N1
Tryon, WW1
Demoulin, C1
Silbert, MV1
Francini, F1
Santana, JG1
Kitrosen, J1
Motta, W1
Panzetti, G1
Martino, A1
Musella, U1
Ruffolo, A1
Cantarini, A1
Benady, DR1
Pariente, J1
Salvatori, A1

Reviews

8 reviews available for cyproheptadine and Anorexia Nervosa

ArticleYear
Use of cyproheptadine to stimulate appetite and body weight gain: A systematic review.
    Appetite, 2019, 06-01, Volume: 137

    Topics: Anorexia Nervosa; Appetite; Appetite Stimulants; Cyproheptadine; Humans; Malnutrition; Randomized Co

2019
Anorexia nervosa.
    Clinical evidence, 2003, Issue:9

    Topics: Anorexia Nervosa; Antidepressive Agents, Tricyclic; Cyproheptadine; Humans; Psychotherapy; Selective

2003
Pharmacologic treatment of eating disorders.
    The Psychiatric clinics of North America, 1984, Volume: 7, Issue:4

    Topics: Anorexia Nervosa; Anticonvulsants; Antidepressive Agents; Antidepressive Agents, Tricyclic; Central

1984
Anorexia nervosa: review of current treatment practices.
    Southern medical journal, 1982, Volume: 75, Issue:9

    Topics: Amitriptyline; Anorexia Nervosa; Behavior Therapy; Chlorpromazine; Cyproheptadine; Enteral Nutrition

1982
Psychopharmacological treatment of anorexia nervosa and bulimia. Review and synthesis.
    The Journal of nervous and mental disease, 1983, Volume: 171, Issue:9

    Topics: Adrenocorticotropic Hormone; Anorexia Nervosa; Antidepressive Agents, Tricyclic; Chlorpromazine; Cyp

1983
The state of research in anorexia nervosa and bulimia.
    Psychiatric developments, 1983,Autumn, Volume: 1, Issue:3

    Topics: Adolescent; Adult; Age Factors; Amenorrhea; Anorexia Nervosa; Behavior Therapy; Body Image; Body Wei

1983
Pharmacotherapy of anorexia nervosa and bulimia.
    Pediatric annals, 1984, Volume: 13, Issue:12

    Topics: Amitriptyline; Anorexia Nervosa; Antidepressive Agents, Tricyclic; Chlorpromazine; Clinical Trials a

1984
[Anorexia nervosa. A general review of recent works].
    Annales medico-psychologiques, 1969, Volume: 1, Issue:3

    Topics: Anorexia Nervosa; Chlorpromazine; Cyproheptadine; Humans; Hypothalamus; Insulin; Parent-Child Relati

1969

Trials

9 trials available for cyproheptadine and Anorexia Nervosa

ArticleYear
Cyproheptadine for anorexia nervosa.
    Lancet (London, England), 1982, Jun-12, Volume: 1, Issue:8285

    Topics: Adolescent; Adult; Amitriptyline; Anorexia Nervosa; Cyproheptadine; Double-Blind Method; Humans; Ran

1982
Pharmacotherapy of anorexia nervosa and bulimia.
    Pediatric annals, 1984, Volume: 13, Issue:12

    Topics: Amitriptyline; Anorexia Nervosa; Antidepressive Agents, Tricyclic; Chlorpromazine; Clinical Trials a

1984
Dopaminergic and serotonergic regulation of growth hormone secretion in anorexia nervosa [proceedings].
    Psychopharmacology bulletin, 1977, Volume: 13, Issue:1

    Topics: Anorexia Nervosa; Clinical Trials as Topic; Cyproheptadine; Dopamine; Growth Hormone; Humans; Levodo

1977
Cyproheptadine in anorexia nervosa [proceedings].
    Psychopharmacology bulletin, 1978, Volume: 14, Issue:2

    Topics: Adolescent; Adult; Anorexia Nervosa; Child; Clinical Trials as Topic; Cyproheptadine; Female; Humans

1978
Cyproheptadine in anorexia nervosa.
    The British journal of psychiatry : the journal of mental science, 1979, Volume: 134

    Topics: Ambulatory Care; Anorexia Nervosa; Behavior Therapy; Body Weight; Clinical Trials as Topic; Cyprohep

1979
Anorexia nervosa. Treatment efficacy of cyproheptadine and amitriptyline.
    Archives of general psychiatry, 1986, Volume: 43, Issue:2

    Topics: Adolescent; Adult; Amitriptyline; Anorexia Nervosa; Body Weight; Clinical Trials as Topic; Cyprohept

1986
Anorexia nervosa and bulimia.
    Annual review of public health, 1986, Volume: 7

    Topics: Adolescent; Anorexia Nervosa; Antidepressive Agents, Tricyclic; Behavior Therapy; Clinical Trials as

1986
Activity measures in anorexia nervosa.
    Archives of general psychiatry, 1985, Volume: 42, Issue:8

    Topics: Adolescent; Adult; Amitriptyline; Ankle; Anorexia Nervosa; Body Weight; Cyproheptadine; Energy Metab

1985
The weight gain effect of periactin in anorexic patients.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1971, Apr-03, Volume: 45, Issue:14

    Topics: Adolescent; Adult; Anorexia Nervosa; Appetite; Body Weight; Child; Child, Preschool; Clinical Trials

1971

Other Studies

18 other studies available for cyproheptadine and Anorexia Nervosa

ArticleYear
[Poteniation of dexamethasone and cyproheptadine. Their use in allergic patients with anorexia and malnutrition].
    El Dia medico, 1962, May-10, Volume: 34

    Topics: Anorexia; Anorexia Nervosa; Anti-Allergic Agents; Cyproheptadine; Dexamethasone; Histamine H1 Antago

1962
Anorexia nervosa. Current perspectives in research.
    The Psychiatric clinics of North America, 1984, Volume: 7, Issue:2

    Topics: Anorexia Nervosa; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Appetite Depressants; Cypr

1984
Depression in anorexia nervosa.
    Psychological medicine, 1982, Volume: 12, Issue:1

    Topics: Anorexia Nervosa; Attitude; Behavior Therapy; Body Weight; Cyproheptadine; Depression; Female; Human

1982
Effects of cyproheptadine on symptoms and attitudes in anorexia nervosa.
    Archives of general psychiatry, 1980, Volume: 37, Issue:9

    Topics: Adolescent; Adult; Anorexia Nervosa; Attitude; Body Weight; Child; Cyproheptadine; Drug Evaluation;

1980
Anorexia and bulimia nervosa: psychiatric approach.
    Current therapy in endocrinology and metabolism, 1994, Volume: 5

    Topics: Anorexia Nervosa; Antidepressive Agents; Bulimia; Cyproheptadine; Fluoxetine; Humans; Nutritional Ph

1994
Attitudinal dimensions in anorexia nervosa.
    Journal of psychiatric research, 1979, Volume: 15, Issue:4

    Topics: Adolescent; Anorexia Nervosa; Attitude; Behavior Therapy; Cyproheptadine; Eating; Female; Humans

1979
Urinary excretion of a quaternary ammonium glucuronide metabolite of cyproheptadine in humans undergoing chronic drug therapy.
    Life sciences, 1977, Dec-15, Volume: 21, Issue:12

    Topics: Adolescent; Adult; Anorexia Nervosa; Body Weight; Cyproheptadine; Female; Glucuronates; Humans

1977
Biological and behavioral predictors to treatment in anorexia nervosa.
    Psychopharmacology bulletin, 1978, Volume: 14, Issue:4

    Topics: Anorexia Nervosa; Behavior Therapy; Cyproheptadine; Humans; Prognosis

1978
Catecholamine metabolism in anorexia nervosa.
    Archives of general psychiatry, 1978, Volume: 35, Issue:4

    Topics: Adolescent; Adult; Anorexia Nervosa; Blood Pressure; Body Weight; Child; Creatinine; Cyproheptadine;

1978
Pretreatment predictors of outcome in anorexia nervosa.
    The British journal of psychiatry : the journal of mental science, 1979, Volume: 134

    Topics: Adolescent; Adult; Anorexia Nervosa; Behavior Therapy; Body Weight; Child; Cyproheptadine; Denial, P

1979
Comparison of bulimic and non-bulimic anorexia nervosa patients during treatment.
    Psychological medicine, 1987, Volume: 17, Issue:4

    Topics: Adolescent; Adult; Amitriptyline; Anorexia Nervosa; Body Image; Bulimia; Cyproheptadine; Female; Hum

1987
[Cyproheptadine, an antihistamine and serotonin antagonist acting on body weight: preliminary report].
    Minerva medica, 1968, Jul-11, Volume: 59, Issue:55

    Topics: Adolescent; Adult; Aged; Anorexia Nervosa; Body Weight; Child; Child, Preschool; Cyproheptadine; Fee

1968
[On the anti-anorexic and eutrophic activity of cyproheptadine in children].
    Minerva medica, 1969, Jun-06, Volume: 60, Issue:45

    Topics: Anorexia Nervosa; Body Weight; Child, Preschool; Cyproheptadine; Feeding and Eating Disorders; Femal

1969
[On the clinical use of cyproheptadine as an anti-anorexic agent and its effects on the nutritional state].
    Minerva medica, 1971, May-12, Volume: 62, Issue:38

    Topics: Adolescent; Adult; Aged; Anorexia Nervosa; Appetite; Body Weight; Child; Child, Preschool; Cyprohept

1971
[Effect of cyproheptadine on appetite and body weight].
    Minerva pediatrica, 1970, Dec-01, Volume: 22, Issue:48

    Topics: Anorexia Nervosa; Appetite; Body Weight; Child; Child, Preschool; Cyproheptadine; Female; Humans; In

1970
Cyproheptadine hydrochloride (Periactin) and anorexia nervosa: a case report.
    The British journal of psychiatry : the journal of mental science, 1970, Volume: 117, Issue:541

    Topics: Adolescent; Anorexia Nervosa; Body Weight; Child; Cyproheptadine; Humans

1970
[Use of an appetite stimulant in anorexia].
    Therapeutique (La Semaine des hopitaux), 1968, Volume: 44, Issue:9

    Topics: Anorexia Nervosa; Child; Child, Preschool; Cyproheptadine; Female; Humans; Infant; Male

1968
[Action of cyproheptadine on the appetite of anorexic and normal children].
    Minerva pediatrica, 1969, Mar-17, Volume: 21, Issue:11

    Topics: Anorexia Nervosa; Appetite; Child; Child, Preschool; Cyproheptadine; Female; Humans; Male

1969