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cyproheptadine and Anaphylaxis

cyproheptadine has been researched along with Anaphylaxis in 24 studies

Cyproheptadine: A serotonin antagonist and a histamine H1 blocker used as antipruritic, appetite stimulant, antiallergic, and for the post-gastrectomy dumping syndrome, etc.
cyproheptadine : The product resulting from the formal oxidative coupling of position 5 of 5H-dibenzo[a,d]cycloheptene with position 4 of 1-methylpiperidine resulting in the formation of a double bond between the two fragments. It is a sedating antihistamine with antimuscarinic and calcium-channel blocking actions. It is used (particularly as the hydrochloride sesquihydrate) for the relief of allergic conditions including rhinitis, conjunctivitis due to inhalant allergens and foods, urticaria and angioedema, and in pruritic skin disorders. Unlike other antihistamines, it is also a seratonin receptor antagonist, making it useful in conditions such as vascular headache and anorexia.

Anaphylaxis: An acute hypersensitivity reaction due to exposure to a previously encountered ANTIGEN. The reaction may include rapidly progressing URTICARIA, respiratory distress, vascular collapse, systemic SHOCK, and death.

Research Excerpts

ExcerptRelevanceReference
"Interstitial fluid pressure (Pif) was measured in skin of pentobarbital-anesthetized rats during anaphylaxis toward dextran and after subdermal injection of histamine by using sharpened glass capillaries (tip diam 5-7 microns) connected to a servo-controlled counterpressure system."3.68Increased negativity of interstitial fluid pressure during the onset stage of inflammatory edema in rat skin. ( Reed, RK; Rodt, SA, 1991)
" By these criteria, we have observed a different degree of anaphylactic reaction depending on the genetic background of the hosts as well as a protection against anaphylactic shock using the antiserotoninic cyproheptadine and, to a lesser extent, by the platelet antiaggregant ticlopidine."3.67[Quantification (by nomograms) of physiopathological parameters in an experimental model of passive anaphylaxis caused by immune complexes]. ( Díaz, R; Portolés, A; Rojo, JM, 1984)
"An animal model of food allergy has been developed in which some aspects of the allergic response could be quantified and the effects of various drugs evaluated."1.26Intestinal anaphylaxis in the rat as a model of food allergy. ( Byars, NE; Ferraresi, RW, 1976)

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-199020 (83.33)18.7374
1990's3 (12.50)18.2507
2000's1 (4.17)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Devlin, JP1
Bauen, A1
Possanza, GJ1
Stewart, PB1
SHERROD, TR1
LOEW, ER1
SCHLOEMER, HF1
DANIELOPOLU, D1
POPESCO, M1
MEZINCESCO, E1
HERXHEIMER, H1
STRESEMANN, E1
GABBIANI, G3
NIELSEN, K1
SELYE, H2
TUCHWEBER, B1
Smith, H1
Ross, JW1
Spicer, BA1
Portolés, A2
Rojo, JM2
Díaz, R2
Lake, AM1
Bloch, KJ1
Sinclair, KJ1
Walker, WA1
Kimura, S1
Watanabe, A2
Takeuchi, M3
Nagata, M2
Harada, M3
Tanaka, Y1
Makiyama, Y1
Mitsui, Y1
Lynch, NR1
Salomon, JC1
Byars, NE1
Ferraresi, RW1
Reed, RK1
Rodt, SA1
Arimura, A1
Nakamura, K1
Frycová, H1
Metys, J1
Schwark, WS1
Tozzi, S1
Roth, FE1
Tabachnick, II1
Pleczarska, A1
Somogyi, A1
Katagiri, K1
Hall, CE1
Ayachi, S1
Hall, O1

Other Studies

24 other studies available for cyproheptadine and Anaphylaxis

ArticleYear
Antiallergic 9-oxo-11-hydroxy-5H,9H-[2]benzopyrano[4,3-g][1]benzopyrans.
    Journal of medicinal chemistry, 1978, Volume: 21, Issue:5

    Topics: Anaphylaxis; Animals; Benzopyrans; Guinea Pigs; Hypersensitivity; In Vitro Techniques; Muscle Contra

1978
Pharmacological properties of antihistamine drugs, benadryl, pyribenzamine and neoantergan.
    The Journal of pharmacology and experimental therapeutics, 1947, Volume: 89, Issue:3

    Topics: Amino Acids; Anaphylaxis; Aniline Compounds; Cyproheptadine; Diphenhydramine; Drug Combinations; Eth

1947
Parasympathyrenic and histaminofrenic action of the antigan (2339-RP); comparative action of atropine and atropine-antergan.
    Journal de physiologie et de pathologie generale, 1945, Volume: 38, Issue:2

    Topics: Anaphylaxis; Aniline Compounds; Atropine; Cyproheptadine; Hypersensitivity; Immune System Diseases

1945
THE EFFECT OF SOME NEW ANTIHISTAMINES ON THE ANAPHYLACTIC MICROSHOCK OF THE GUINEA-PIG.
    British journal of pharmacology and chemotherapy, 1963, Volume: 21

    Topics: Anaphylaxis; Animals; Anti-Allergic Agents; Antipsychotic Agents; Cyclic S-Oxides; Cyproheptadine; G

1963
ANAPHYLACTOID INFLAMMATION AND MASTOPEXIS; THE ROLE OF THE MAST CELL.
    Archives of pathology, 1964, Volume: 78

    Topics: Anaphylaxis; Cyproheptadine; Edema; Inflammation; Iron-Dextran Complex; Mast Cells; Pathology; Pharm

1964
EFFECT OF CYPROHEPTADINE UPON TWO FORMS OF THE THROMBOHEMORRHAGIC PHENOMENON (THP).
    Angiologica, 1965, Volume: 2

    Topics: Anaphylaxis; Cyproheptadine; Rats; Research; Shock; Shock, Hemorrhagic; Thrombosis

1965
Rat passive peritoneal anaphylaxis following sensitisation with guinea pig antiserum: an immediate hypersensitivity reaction without histamine release.
    International archives of allergy and applied immunology, 1980, Volume: 62, Issue:2

    Topics: Anaphylaxis; Animals; Antigens; Blood Proteins; Coloring Agents; Cyproheptadine; Guinea Pigs; Histam

1980
[Quantification (by nomograms) of physiopathological parameters in an experimental model of passive anaphylaxis caused by immune complexes].
    Revista espanola de fisiologia, 1984, Volume: 40, Issue:3

    Topics: Anaphylaxis; Animals; Cyproheptadine; Immune Complex Diseases; Mathematics; Mice; Mice, Inbred Strai

1984
Anaphylactic release of intestinal goblet cell mucus.
    Immunology, 1980, Volume: 39, Issue:2

    Topics: Anaphylaxis; Animals; Antigens; Cell Membrane Permeability; Cyproheptadine; Female; Immunization, Pa

1980
Suppressive effects of antihistaminic and/or anti-PAF agents on passive anaphylactic shock in mice sensitized with allogeneic monoclonal IgE and IgG1 antibodies and hyperimmune serum.
    Immunological investigations, 1998, Volume: 27, Issue:6

    Topics: Anaphylaxis; Animals; Antibodies, Monoclonal; Cattle; Cyproheptadine; Female; Histamine H1 Antagonis

1998
Anti-CD44 monoclonal antibody (IM7) induces murine systemic shock mediated by platelet activating factor.
    Journal of autoimmunity, 2002, Volume: 18, Issue:1

    Topics: Anaphylaxis; Animals; Anti-Allergic Agents; Antibodies, Monoclonal; Azepines; Capillary Permeability

2002
Passive local anaphylaxis: demonstration of antitumor activity and complementation of intratumor BCG.
    Journal of the National Cancer Institute, 1977, Volume: 58, Issue:4

    Topics: Anaphylaxis; Animals; BCG Vaccine; Cyproheptadine; Female; Fibrosarcoma; Immunity; Immunotherapy; Li

1977
Intestinal anaphylaxis in the rat as a model of food allergy.
    Clinical and experimental immunology, 1976, Volume: 24, Issue:2

    Topics: Anaphylaxis; Animals; Antigens; Capillary Permeability; Cromolyn Sodium; Cyproheptadine; Disease Mod

1976
Increased negativity of interstitial fluid pressure during the onset stage of inflammatory edema in rat skin.
    The American journal of physiology, 1991, Volume: 260, Issue:6 Pt 2

    Topics: Anaphylaxis; Animals; Capillary Permeability; Cyproheptadine; Dermatitis; Dextrans; Edema; Female; H

1991
Production of active and passive anaphylactic shock in the WBB6F1 mouse, a mast cell-deficient strain.
    Experientia, 1990, Jul-15, Volume: 46, Issue:7

    Topics: Anaphylaxis; Animals; Cyproheptadine; Female; Histamine; Immunization, Passive; Mast Cells; Mice; Mi

1990
[Anti-allergic properties of pipethiaden--a new preventive agent for migraine].
    Ceskoslovenska farmacie, 1989, Volume: 38, Issue:6

    Topics: Anaphylaxis; Animals; Cyproheptadine; Female; Guinea Pigs; Mice; Migraine Disorders; Passive Cutaneo

1989
Influence of mouse genotype on passive systemic anaphylaxis by immune complexes.
    Infection and immunity, 1986, Volume: 54, Issue:3

    Topics: Anaphylaxis; Animals; Antigen-Antibody Complex; Brucella abortus; Cyproheptadine; Dose-Response Rela

1986
Pharmacologic management of allergic diseases.
    The Veterinary clinics of North America, 1974, Volume: 4, Issue:1

    Topics: Administration, Oral; Administration, Topical; Anaphylaxis; Animals; Anti-Inflammatory Agents; Cromo

1974
The pharmacology of azatadine, a potential antiallergy drug.
    Agents and actions, 1974, Volume: 4, Issue:4

    Topics: Anaphylaxis; Animals; Cyproheptadine; Dose-Response Relationship, Drug; Female; Guinea Pigs; Histami

1974
Pharmacological studies on some anaphylactic reactions in mice.
    Archivum immunologiae et therapiae experimentalis, 1974, Volume: 22, Issue:6

    Topics: Anaphylaxis; Animals; Carrageenan; Cell Membrane; Complement Inactivator Proteins; Cromolyn Sodium;

1974
Effect of cyproheptadine upon acute inflammation produced by various agents.
    Medicina et pharmacologia experimentalis. International journal of experimental medicine, 1967, Volume: 17, Issue:3

    Topics: Acute Disease; Anaphylaxis; Animals; Cyproheptadine; Edema; Female; Histamine H1 Antagonists; Histam

1967
Action of cyproheptadine on generalized and local anaphylactoid oedema.
    International archives of allergy and applied immunology, 1968, Volume: 33, Issue:6

    Topics: Anaphylaxis; Animals; Cyproheptadine; Dextrans; Edema; Histamine Release; Injections, Subcutaneous;

1968
Susceptibility of four types of cutaneous anaphylaxis in the mouse to antihistaminics.
    International archives of allergy and applied immunology, 1968, Volume: 34, Issue:4

    Topics: Anaphylaxis; Animals; Antigens; Capillary Permeability; Cyproheptadine; Diphenhydramine; Histamine;

1968
Effect of cortisol and cyproheptadine on anaphylactoid and arthritic responses of the rat to dextran.
    Archives internationales de pharmacodynamie et de therapie, 1973, Volume: 201, Issue:2

    Topics: Acute Disease; Anaphylaxis; Animals; Arthritis; Chronic Disease; Cyproheptadine; Dextrans; Disease M

1973