cyproheptadine has been researched along with Alloxan Diabetes in 10 studies
Cyproheptadine: A serotonin antagonist and a histamine H1 blocker used as antipruritic, appetite stimulant, antiallergic, and for the post-gastrectomy dumping syndrome, etc.
cyproheptadine : The product resulting from the formal oxidative coupling of position 5 of 5H-dibenzo[a,d]cycloheptene with position 4 of 1-methylpiperidine resulting in the formation of a double bond between the two fragments. It is a sedating antihistamine with antimuscarinic and calcium-channel blocking actions. It is used (particularly as the hydrochloride sesquihydrate) for the relief of allergic conditions including rhinitis, conjunctivitis due to inhalant allergens and foods, urticaria and angioedema, and in pruritic skin disorders. Unlike other antihistamines, it is also a seratonin receptor antagonist, making it useful in conditions such as vascular headache and anorexia.
| Excerpt | Relevance | Reference |
|---|---|---|
| "beta cells in islets of Langerhans were studied in Sprague-Dawley rats dosed by gavage with 0 (control), 75, 150, 250 or 300 mg/kg body wt/day S-H 966 BS [1-(1-oxido-4-thiomorpholino)-3-(1-piperazinyl)], an isoquinoline derivative." | 1.27 | Cytoplasmic vacuolation of pancreatic beta cells of rats after oral administration of a derivative of isoquinoline. ( Kast, A; Ueberberg, H, 1986) |
| "1 In nialamide-treated mice, L-5-hydroxytryptophan produced a dose-dependent hypoglycaemic response which was independent of whether the animals had been fed or fasted." | 1.25 | The hypoglycaemic effect of 5-hydroxytryptophan. ( Furman, BL, 1974) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (60.00) | 18.7374 |
| 1990's | 2 (20.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 2 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hafez, HM | 1 |
| Abdel-Hakeem, EA | 1 |
| Hassanein, H | 1 |
| Sharma, N | 1 |
| Sankrityayan, H | 1 |
| Kale, A | 1 |
| Gaikwad, AB | 1 |
| Fischer, LJ | 2 |
| Rickert, DE | 1 |
| Shoji, M | 1 |
| Sato, H | 1 |
| Hirai, Y | 1 |
| Oguni, Y | 1 |
| Sugimoto, C | 1 |
| Morishita, S | 1 |
| Ito, C | 1 |
| Chatterjee, AK | 1 |
| Varayotha, V | 1 |
| Onishi, E | 1 |
| Yamada, T | 1 |
| Yamada, K | 1 |
| Inoue, H | 2 |
| Seyama, Y | 2 |
| Yamashita, S | 2 |
| Martin, S | 1 |
| Kolb-Bachofen, V | 1 |
| Kiesel, U | 1 |
| Kolb, H | 1 |
| Goto, M | 1 |
| Inoue, O | 1 |
| Yumioka, E | 1 |
| Kast, A | 1 |
| Ueberberg, H | 1 |
| Furman, BL | 1 |
1 review available for cyproheptadine and Alloxan Diabetes
| Article | Year |
|---|---|
Pancreatic islet-cell toxicity.
Topics: Alloxan; Animals; Chelating Agents; Cyproheptadine; Diabetes Mellitus; Diabetes Mellitus, Experiment | 1975 |
9 other studies available for cyproheptadine and Alloxan Diabetes
| Article | Year |
|---|---|
Rupatadine, a dual antagonist of histamine and platelet-activating factor (PAF), attenuates experimentally induced diabetic nephropathy in rats.
Topics: Animals; Blood Glucose; Cyclin-Dependent Kinase Inhibitor p21; Cyproheptadine; Cystatin C; Diabetes | 2020 |
Role of SET7/9 in the progression of ischemic renal injury in diabetic and non-diabetic rats.
Topics: Animals; Biomarkers; Cyproheptadine; Diabetes Mellitus, Experimental; Disease Progression; Histone-L | 2020 |
[Pharmacological effects of Gosha-jinki-gan-ryo extract: effects on experimental diabetes].
Topics: Aldehyde Reductase; Animals; Blood Glucose; Cyproheptadine; Diabetes Mellitus, Experimental; Diabeti | 1992 |
Interactions of diabetogenic compounds: cyproheptadine and alloxan.
Topics: Alloxan; Animals; Cyproheptadine; Diabetes Mellitus, Experimental; Drug Interactions; Insulin; Iodin | 1991 |
[Comparison of experimental diabetes induced by streptozotocin and cyproheptadine].
Topics: Amylases; Animals; Blood Glucose; Cyproheptadine; Diabetes Mellitus, Experimental; Glucose Tolerance | 1986 |
Pathogenesis of low dose streptozotocin induced diabetes in mice: requirement for alpha 1-adrenoceptor activation and vasoactive amine release.
Topics: Animals; Cromolyn Sodium; Cyproheptadine; Diabetes Mellitus, Experimental; Histamine Antagonists; Me | 1989 |
[Comparative effects of traditional Chinese medicines (dai-saiko-to, hatimi-zio-gan and byakko-ka-ninzin-to) on experimental diabetes and hyperlipidemia].
Topics: Animals; Blood Glucose; Body Weight; Cholesterol; Cyproheptadine; Diabetes Mellitus, Experimental; D | 1989 |
Cytoplasmic vacuolation of pancreatic beta cells of rats after oral administration of a derivative of isoquinoline.
Topics: Alkaline Phosphatase; Animals; Cyproheptadine; Cytoplasm; Diabetes Mellitus, Experimental; Dose-Resp | 1986 |
The hypoglycaemic effect of 5-hydroxytryptophan.
Topics: 5-Hydroxytryptophan; Adipose Tissue; Animals; Blood Glucose; Cyproheptadine; Diabetes Mellitus, Expe | 1974 |