cyproheptadine has been researched along with Allergic Encephalomyelitis in 3 studies
Cyproheptadine: A serotonin antagonist and a histamine H1 blocker used as antipruritic, appetite stimulant, antiallergic, and for the post-gastrectomy dumping syndrome, etc.
cyproheptadine : The product resulting from the formal oxidative coupling of position 5 of 5H-dibenzo[a,d]cycloheptene with position 4 of 1-methylpiperidine resulting in the formation of a double bond between the two fragments. It is a sedating antihistamine with antimuscarinic and calcium-channel blocking actions. It is used (particularly as the hydrochloride sesquihydrate) for the relief of allergic conditions including rhinitis, conjunctivitis due to inhalant allergens and foods, urticaria and angioedema, and in pruritic skin disorders. Unlike other antihistamines, it is also a seratonin receptor antagonist, making it useful in conditions such as vascular headache and anorexia.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Experimental allergic encephalomyelitis (EAE) is an autoimmune syndrome that can be induced in Lewis rats by myelin basic protein (BP) in complete Freund's adjuvant (CFA)." | 7.67 | Modification of the clinical and histopathologic expression of experimental allergic encephalomyelitis by the vasoactive amine antagonist cyproheptadine. ( Taguiam, JM; Waxman, FJ; Whitacre, CC, 1984) |
| "Experimental allergic encephalomyelitis (EAE) is an autoimmune syndrome that can be induced in Lewis rats by myelin basic protein (BP) in complete Freund's adjuvant (CFA)." | 3.67 | Modification of the clinical and histopathologic expression of experimental allergic encephalomyelitis by the vasoactive amine antagonist cyproheptadine. ( Taguiam, JM; Waxman, FJ; Whitacre, CC, 1984) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Waxman, FJ | 1 |
| Taguiam, JM | 1 |
| Whitacre, CC | 1 |
| Moore, MJ | 1 |
| Matthews, JM | 1 |
| Matthews, TK | 1 |
| Behan, PO | 1 |
| Kies, MW | 1 |
| Rosenthale, ME | 1 |
| Datko, LJ | 1 |
| Kassarich, J | 1 |
| Schneider, F | 1 |
3 other studies available for cyproheptadine and Allergic Encephalomyelitis
| Article | Year |
|---|---|
Modification of the clinical and histopathologic expression of experimental allergic encephalomyelitis by the vasoactive amine antagonist cyproheptadine.
Topics: Animals; Bordetella pertussis; Capillary Permeability; Cyproheptadine; Encephalomyelitis, Autoimmune | 1984 |
Reaginic antibody in experimental allergic encephalomyelitis. II. Histamine and serotonin blockade.
Topics: Adrenal Glands; Animals; Body Weight; Bordetella pertussis; Cyproheptadine; Drug Therapy, Combinatio | 1974 |
Chemotherapy of experimental allergic encephalomyelitis (EAE).
Topics: Allopurinol; Aminocaproates; Analgesics; Animals; Antineoplastic Agents; Azathioprine; Body Weight; | 1969 |